SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ubj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		3 / 3 ILE A 186
ASP A 287
PHE A 105
 None
 0.61A 1uwjB-5ubjA:
undetectable		 1uwjB-5ubjA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		5 / 10 PHE A 172
ALA A 101
PHE A 124
LEU A 144
THR A 103
 None
 1.21A 3a3yA-5ubjA:
undetectable		 3a3yA-5ubjA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		4 / 5 ILE A 186
THR A 216
PHE A 171
TYR A 169
 None
 1.37A 3em0A-5ubjA:
undetectable		 3em0A-5ubjA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAK_A_EV1A415_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		5 / 9 TYR A 126
MET A 184
ILE A 114
PHE A 105
ILE A 186
 None
 1.46A 3iakA-5ubjA:
undetectable		 3iakA-5ubjA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		5 / 10 VAL A 212
ILE A 179
ALA A 182
ILE A 149
VAL A 156
 None
 1.07A 3me6A-5ubjA:
undetectable		 3me6A-5ubjA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		3 / 3 PHE A 105
GLN A 213
PHE A 189
 None
CA  A 401 (-2.8A)
None
 0.75A 3rv5A-5ubjA:
undetectable		 3rv5A-5ubjA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		4 / 6 LEU A  61
MET A  95
LEU A 115
VAL A 161
 None
 1.16A 4okbA-5ubjA:
undetectable		 4okbA-5ubjA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		3 / 3 PRO A  55
LEU A 300
SER A 284
 None
 0.77A 5fsaB-5ubjA:
undetectable		 5fsaB-5ubjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		5 / 12 ILE A 292
LEU A 226
TRP A  32
GLY A  25
TYR A  30
 None
 1.06A 5nnaC-5ubjA:
undetectable		 5nnaC-5ubjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.46A 5wz1A-5ubjA:
undetectable		 5wz1A-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.45A 5wz1B-5ubjA:
undetectable		 5wz1B-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.43A 5wz1C-5ubjA:
undetectable		 5wz1C-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.45A 5wz1D-5ubjA:
undetectable		 5wz1D-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.44A 5wz1E-5ubjA:
undetectable		 5wz1E-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.43A 5wz1F-5ubjA:
undetectable		 5wz1F-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.46A 5wz1G-5ubjA:
undetectable		 5wz1G-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		6 / 12 GLY A 233
GLY A 236
HIS A 278
GLU A 210
ASP A 280
ILE A 228
 None
None
CA  A 401 (-3.7A)
CA  A 403 ( 4.2A)
None
None
 1.42A 5wz1H-5ubjA:
undetectable		 5wz1H-5ubjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2
(Aspergillus
nidulans) 		3 / 3 ARG A 283
PHE A 171
PHE A 105
 None
 1.08A 6nknC-5ubjA:
undetectable
6nknJ-5ubjA:
undetectable		 6nknC-5ubjA:
22.35
6nknJ-5ubjA:
10.37