SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ubu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		4 / 6 SER A 266
ALA A 267
THR A 317
ASN A 310
 None
 1.07A 1yvpB-5ubuA:
undetectable		 1yvpB-5ubuA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 211
PRO A 174
GLY A  38
GLU A  94
LEU A 244
 None
 1.02A 2plwA-5ubuA:
undetectable		 2plwA-5ubuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		4 / 8 ILE A 103
LEU A 213
ILE A 167
THR A 202
 None
 0.59A 2w9sE-5ubuA:
undetectable		 2w9sE-5ubuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		4 / 7 GLY A 168
ILE A 215
THR A  57
MET A 106
 NA  A 401 ( 4.5A)
None
None
None
 1.00A 2xrhA-5ubuA:
undetectable		 2xrhA-5ubuA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 197
PRO A 165
ILE A 201
ASN A 257
VAL A 101
 None
 1.29A 2zznA-5ubuA:
undetectable		 2zznA-5ubuA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 188
ASP A 185
GLY A 319
ASN A 186
LEU A 204
 None
 0.98A 3eeyA-5ubuA:
undetectable		 3eeyA-5ubuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 188
ASP A 185
GLY A 319
ASN A 186
LEU A 204
 None
 0.99A 3eeyC-5ubuA:
undetectable		 3eeyC-5ubuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 188
ASP A 185
GLY A 319
ASN A 186
LEU A 204
 None
 1.03A 3eeyD-5ubuA:
undetectable		 3eeyD-5ubuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 188
ASP A 185
GLY A 319
ASN A 186
LEU A 204
 None
 0.95A 3eeyE-5ubuA:
undetectable		 3eeyE-5ubuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 188
ASP A 185
GLY A 319
ASN A 186
LEU A 204
 None
 1.01A 3eeyF-5ubuA:
undetectable		 3eeyF-5ubuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		6 / 9 LEU A 213
GLY A 210
ALA A  93
ASP A  97
VAL A 101
ILE A  99
 None
 1.32A 3oxvA-5ubuA:
undetectable		 3oxvA-5ubuA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 210
ALA A  93
ASP A  97
VAL A 101
ILE A  99
 None
 1.04A 3tkgC-5ubuA:
undetectable		 3tkgC-5ubuA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 PRO A 184
HIS A 166
GLY A 309
ASP A 217
GLY A 168
 None
None
None
NA  A 402 ( 2.3A)
NA  A 401 ( 4.5A)
 1.16A 4lxzA-5ubuA:
undetectable		 4lxzA-5ubuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 PRO A 184
HIS A 166
GLY A 309
ASP A 217
GLY A 168
 None
None
None
NA  A 402 ( 2.3A)
NA  A 401 ( 4.5A)
 1.16A 4lxzC-5ubuA:
undetectable		 4lxzC-5ubuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 PRO A 314
HIS A 219
GLY A 229
ASP A 217
LEU A 182
 None
NA  A 402 (-3.5A)
None
NA  A 402 ( 2.3A)
None
 1.24A 5eeiA-5ubuA:
undetectable		 5eeiA-5ubuA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 PRO A 314
HIS A 219
GLY A 229
ASP A 217
LEU A 182
 None
NA  A 402 (-3.5A)
None
NA  A 402 ( 2.3A)
None
 1.22A 5eeiB-5ubuA:
undetectable		 5eeiB-5ubuA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 SER A 236
GLY A 168
GLY A 216
GLN A  84
ASP A 313
 None
NA  A 401 ( 4.5A)
None
None
NA  A 401 ( 4.4A)
 1.02A 5kpcB-5ubuA:
undetectable		 5kpcB-5ubuA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		3 / 3 GLY A  63
VAL A 143
MET A 145
 None
 0.66A 5ycpA-5ubuA:
undetectable		 5ycpA-5ubuA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 216
GLY A 189
ASN A  85
ASP A  56
ASP A 217
 None
None
None
None
NA  A 402 ( 2.3A)
 1.15A 5yn6A-5ubuA:
undetectable		 5yn6A-5ubuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 216
GLY A 189
ASN A  85
ASP A  56
ASP A 217
 None
None
None
None
NA  A 402 ( 2.3A)
 1.19A 5yniA-5ubuA:
undetectable		 5yniA-5ubuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 216
GLY A 189
ASN A  85
ASP A  56
ASP A 217
 None
None
None
None
NA  A 402 ( 2.3A)
 1.17A 5ynmA-5ubuA:
undetectable		 5ynmA-5ubuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		4 / 8 GLY A 115
ILE A 116
ASP A 217
PRO A  83
 None
None
NA  A 402 ( 2.3A)
None
 1.03A 6ag0C-5ubuA:
undetectable		 6ag0C-5ubuA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 5ubu PUTATIVE
ACETAMIDASE/FORMAMID
ASE
(Yersinia
enterocolitica) 		3 / 3 TRP A   3
ILE A 201
GLU A 104
 None
 0.86A 6hcxA-5ubuA:
undetectable		 6hcxA-5ubuA:
18.06