SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ubw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.16A 1rs6B-5ubwA:
undetectable		 1rs6B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.10A 1rs7B-5ubwA:
undetectable		 1rs7B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.14A 1zzqB-5ubwA:
undetectable		 1zzqB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		3 / 3 ARG A 158
SER A 161
TYR A 335
 None
 0.86A 2q2hA-5ubwA:
undetectable
2q2hB-5ubwA:
undetectable		 2q2hA-5ubwA:
undetectable
2q2hB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 11 GLY A 286
THR A 292
ILE A 293
LEU A 217
THR A 169
 None
 1.22A 3bexC-5ubwA:
undetectable
3bexD-5ubwA:
undetectable		 3bexC-5ubwA:
undetectable
3bexD-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 11 GLY A 286
THR A 292
ILE A 293
LEU A 217
THR A 169
 None
 1.30A 3bf1A-5ubwA:
undetectable
3bf1B-5ubwA:
undetectable		 3bf1A-5ubwA:
undetectable
3bf1B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 11 GLY A 286
THR A 292
ILE A 293
LEU A 217
THR A 169
 None
 1.24A 3bf1C-5ubwA:
undetectable
3bf1D-5ubwA:
undetectable		 3bf1C-5ubwA:
undetectable
3bf1D-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.18A 3n62A-5ubwA:
undetectable		 3n62A-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.24A 3n62B-5ubwA:
undetectable		 3n62B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.26A 3n66B-5ubwA:
undetectable		 3n66B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 LEU A 217
THR A 169
GLY A 286
THR A 292
ILE A 293
 None
 1.26A 4o5fA-5ubwA:
undetectable
4o5fB-5ubwA:
undetectable		 4o5fA-5ubwA:
undetectable
4o5fB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.25A 5vunA-5ubwA:
undetectable		 5vunA-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.22A 5vunB-5ubwA:
undetectable		 5vunB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.21A 5vuoB-5ubwA:
undetectable		 5vuoB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ubw DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.23A 6auuB-5ubwA:
undetectable		 6auuB-5ubwA:
undetectable