SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uc1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.76A 1a28A-5uc1A:
25.0		 1a28A-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1a28B-5uc1A:
25.0		 1a28B-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
 0.86A 1gs4A-5uc1A:
23.3		 1gs4A-5uc1A:
51.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 ( 4.7A)
 1.00A 1gs4A-5uc1A:
23.3		 1gs4A-5uc1A:
51.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.67A 1m2zA-5uc1A:
26.2		 1m2zA-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.78A 1m2zA-5uc1A:
26.2		 1m2zA-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1m2zD-5uc1A:
26.1		 1m2zD-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
VAL A 567
MET A 600
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.78A 1nhzA-5uc1A:
26.9		 1nhzA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
GLY A 563
GLN A 566
VAL A 567
MET A 600
LEU A 604
ARG A 607
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.68A 1nhzA-5uc1A:
26.9		 1nhzA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
GLY A 563
GLN A 566
VAL A 567
MET A 600
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.38A 1nhzA-5uc1A:
26.9		 1nhzA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 VAL A 567
MET A 600
LEU A 604
ARG A 607
GLN A 641
 None
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
CPS  A 803 (-3.5A)
 1.39A 1nhzA-5uc1A:
26.9		 1nhzA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.81A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 0.96A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
GLN A 638
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 1.05A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.75A 1p93B-5uc1A:
25.1		 1p93B-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
GLN A 638
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 1.00A 1p93C-5uc1A:
25.2		 1p93C-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1p93C-5uc1A:
25.2		 1p93C-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.78A 1p93D-5uc1A:
25.0		 1p93D-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 TRP A 596
MET A 600
LEU A 604
GLN A 641
 None
None
486  A 801 ( 3.8A)
CPS  A 803 (-3.5A)
 1.17A 1p93D-5uc1A:
25.0		 1p93D-5uc1A:
75.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 4 VAL A 645
ALA A 601
LEU A 666
PHE A 602
 None
CPS  A 803 ( 3.9A)
None
None
 1.06A 1q97B-5uc1A:
undetectable		 1q97B-5uc1A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
 0.87A 1sqnA-5uc1A:
24.6		 1sqnA-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
 0.78A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
LEU A 562
GLN A 566
MET A 597
MET A 600
MET A 642
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
 0.83A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
LEU A 559
LEU A 604
MET A 642
LEU A 617
 486  A 801 ( 4.8A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
None
 0.99A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
MET A 635
LEU A 604
MET A 642
LEU A 617
 486  A 801 ( 4.8A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
None
 0.85A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 1ya3A-5uc1A:
22.1		 1ya3A-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLN A 566
LEU A 604
ARG A 607
MET A 635
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.09A 1ya3A-5uc1A:
22.1		 1ya3A-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.76A 1ya3B-5uc1A:
21.7		 1ya3B-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 1ya3C-5uc1A:
21.7		 1ya3C-5uc1A:
56.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.71A 1z95A-5uc1A:
22.6		 1z95A-5uc1A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLY A 563
GLN A 566
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
 0.76A 1z95A-5uc1A:
22.6		 1z95A-5uc1A:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.86A 1zucB-5uc1A:
24.6		 1zucB-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.67A 1zucB-5uc1A:
24.6		 1zucB-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
MET A 597
MET A 600
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.81A 1zucB-5uc1A:
24.6		 1zucB-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
LEU A 604
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.13A 2aa5A-5uc1A:
22.8		 2aa5A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 2aa5A-5uc1A:
22.8		 2aa5A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.74A 2aa5B-5uc1A:
23.0		 2aa5B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.12A 2aa6A-5uc1A:
23.2		 2aa6A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.85A 2aa6A-5uc1A:
23.2		 2aa6A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.84A 2aa6B-5uc1A:
23.1		 2aa6B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
ARG A 607
PHE A 619
MET A 635
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 4.7A)
 1.28A 2ab2A-5uc1A:
23.2		 2ab2A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.82A 2ab2A-5uc1A:
23.2		 2ab2A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 6 LEU A 559
LEU A 562
LEU A 604
CYH A 639
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 ( 3.8A)
486  A 801 ( 3.9A)
 0.74A 2ab2A-5uc1A:
23.2		 2ab2A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
ARG A 607
PHE A 619
MET A 635
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 4.7A)
 1.30A 2ab2B-5uc1A:
23.2		 2ab2B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.85A 2ab2B-5uc1A:
23.2		 2ab2B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 LEU A 559
LEU A 562
LEU A 604
CYH A 639
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 ( 3.8A)
486  A 801 ( 3.9A)
 0.77A 2ab2B-5uc1A:
23.1		 2ab2B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
LEU A 562
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.75A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 1.01A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 1.11A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
LEU A 604
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.04A 2oaxA-5uc1A:
21.8		 2oaxA-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.76A 2oaxA-5uc1A:
21.8		 2oaxA-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.61A 2oaxB-5uc1A:
21.8		 2oaxB-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
LEU A 604
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.22A 2oaxC-5uc1A:
21.3		 2oaxC-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.67A 2oaxC-5uc1A:
21.3		 2oaxC-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.59A 2oaxC-5uc1A:
21.3		 2oaxC-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
LEU A 604
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.19A 2oaxD-5uc1A:
22.2		 2oaxD-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.70A 2oaxD-5uc1A:
22.2		 2oaxD-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.70A 2oaxD-5uc1A:
22.2		 2oaxD-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 0.91A 2oaxE-5uc1A:
22.0		 2oaxE-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.60A 2oaxE-5uc1A:
22.0		 2oaxE-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.72A 2oaxF-5uc1A:
22.5		 2oaxF-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.64A 2oaxF-5uc1A:
22.5		 2oaxF-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.14A 2oz7A-5uc1A:
23.1		 2oz7A-5uc1A:
51.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.13A 2q7iA-5uc1A:
22.8		 2q7iA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.85A 2q7iA-5uc1A:
22.8		 2q7iA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.00A 2q7jA-5uc1A:
23.2		 2q7jA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.77A 2q7jA-5uc1A:
23.2		 2q7jA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.69A 2q7jA-5uc1A:
23.2		 2q7jA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.86A 2q7kA-5uc1A:
23.1		 2q7kA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.14A 2q7kA-5uc1A:
23.1		 2q7kA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.82A 2q7lA-5uc1A:
23.3		 2q7lA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.09A 2q7lA-5uc1A:
23.3		 2q7lA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 562
GLY A 563
GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.75A 2w8yA-5uc1A:
25.1		 2w8yA-5uc1A:
56.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 2w8yB-5uc1A:
25.1		 2w8yB-5uc1A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.61A 2yhdA-5uc1A:
23.1		 2yhdA-5uc1A:
51.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLY A 563
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 0.87A 2yhdA-5uc1A:
23.1		 2yhdA-5uc1A:
51.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
 0.59A 2yhdA-5uc1A:
23.1		 2yhdA-5uc1A:
51.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
LEU A 562
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
None
486  A 801 (-3.5A)
 0.74A 2yloA-5uc1A:
23.1		 2yloA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.82A 2yloA-5uc1A:
23.1		 2yloA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.66A 2ylpA-5uc1A:
23.3		 2ylpA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
LEU A 562
GLN A 566
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
 0.63A 2ylpA-5uc1A:
23.3		 2ylpA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.65A 2ylqA-5uc1A:
23.3		 2ylqA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
LEU A 562
GLN A 566
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
 0.63A 2ylqA-5uc1A:
23.3		 2ylqA-5uc1A:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ILE A 624
MET A 635
LEU A 559
LEU A 604
ARG A 607
 None
486  A 801 ( 4.7A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 1.16A 2zzaA-5uc1A:
undetectable		 2zzaA-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ILE A 624
MET A 635
LEU A 559
LEU A 604
ARG A 607
 None
486  A 801 ( 4.7A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 1.20A 2zzaB-5uc1A:
undetectable		 2zzaB-5uc1A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
CYH A 639
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.9A)
 0.75A 3cldA-5uc1A:
26.0		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 9 LEU A 559
LEU A 562
MET A 600
ALA A 601
MET A 635
MET A 642
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.83A 3cldA-5uc1A:
26.1		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 9 LEU A 562
TRP A 596
MET A 600
ALA A 601
MET A 635
MET A 642
 486  A 801 ( 4.8A)
None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.88A 3cldA-5uc1A:
26.1		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 635
CYH A 639
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 ( 3.9A)
 0.77A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 LEU A 559
ALA A 601
LEU A 604
MET A 642
 486  A 801 (-4.7A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 0.68A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 MET A 600
ALA A 601
LEU A 604
MET A 642
 None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 0.70A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.82A 3d90A-5uc1A:
24.6		 3d90A-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 3d90B-5uc1A:
24.4		 3d90B-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.72A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
ARG A 607
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.91A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.88A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.80A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.74A 3gn8B-5uc1A:
25.6		 3gn8B-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.92A 3gn8B-5uc1A:
25.6		 3gn8B-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
VAL A 567
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.55A 3h52A-5uc1A:
20.8		 3h52A-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		9 / 12 GLY A 563
GLY A 564
GLN A 566
VAL A 567
LEU A 604
ARG A 607
MET A 635
CYH A 639
MET A 642
 486  A 801 (-3.7A)
486  A 801 ( 3.8A)
486  A 801 (-2.8A)
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 ( 3.9A)
486  A 801 ( 3.8A)
 0.53A 3h52B-5uc1A:
20.7		 3h52B-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
MET A 597
LEU A 604
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.65A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
TRP A 596
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.71A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 564
GLN A 566
VAL A 567
TRP A 596
MET A 597
 486  A 801 ( 3.8A)
486  A 801 (-2.8A)
None
None
CPS  A 803 ( 3.9A)
 1.07A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
VAL A 567
MET A 597
PHE A 619
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-4.7A)
 1.07A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
VAL A 567
TRP A 596
MET A 597
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
None
None
CPS  A 803 ( 3.9A)
 1.10A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
TRP A 596
MET A 597
LEU A 604
MET A 642
 486  A 801 ( 4.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 1.47A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
MET A 597
LEU A 604
ARG A 607
MET A 635
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.74A 3h52D-5uc1A:
21.1		 3h52D-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 LEU A 559
ASN A 560
TRP A 596
MET A 600
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
None
None
 0.60A 3h52D-5uc1A:
21.1		 3h52D-5uc1A:
87.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 LEU A 559
LEU A 562
LEU A 604
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.32A 3hm1B-5uc1A:
22.5		 3hm1B-5uc1A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		3 / 3 VAL A 567
VAL A 571
TRP A 596
 None
 0.92A 3l8lA-5uc1A:
undetectable
3l8lB-5uc1A:
undetectable		 3l8lA-5uc1A:
undetectable
3l8lB-5uc1A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.70A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.88A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.79A 3mnoA-5uc1A:
24.8		 3mnoA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.67A 3mnoA-5uc1A:
24.8		 3mnoA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 6 MET A 556
LEU A 559
MET A 600
GLN A 638
 None
486  A 801 (-4.7A)
None
486  A 801 (-4.6A)
 1.23A 3mnoA-5uc1A:
24.8		 3mnoA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.78A 3mnpA-5uc1A:
25.4		 3mnpA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.71A 3mnpA-5uc1A:
25.4		 3mnpA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 6 MET A 556
LEU A 559
MET A 600
GLN A 638
 None
486  A 801 (-4.7A)
None
486  A 801 (-4.6A)
 1.23A 3mnpA-5uc1A:
25.4		 3mnpA-5uc1A:
90.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 10 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.78A 3ollA-5uc1A:
21.9		 3ollA-5uc1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.82A 3olsA-5uc1A:
23.1		 3olsA-5uc1A:
16.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.73A 3vhuA-5uc1A:
23.4		 3vhuA-5uc1A:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
LEU A 562
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
None
486  A 801 (-3.5A)
 0.73A 3zqtA-5uc1A:
23.3		 3zqtA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.85A 3zqtA-5uc1A:
23.3		 3zqtA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 0.92A 4fn9A-5uc1A:
25.1		 4fn9A-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ALA A 601
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 4fn9A-5uc1A:
25.1		 4fn9A-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.00A 4fn9B-5uc1A:
25.4		 4fn9B-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 4fn9B-5uc1A:
25.4		 4fn9B-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.74A 4fn9B-5uc1A:
25.4		 4fn9B-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.69A 4hlwA-5uc1A:
23.1		 4hlwA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.79A 4hlwA-5uc1A:
23.1		 4hlwA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
ARG A 607
MET A 635
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
 1.02A 4ltwA-5uc1A:
25.2		 4ltwA-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.81A 4ltwA-5uc1A:
25.2		 4ltwA-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 TRP A 596
MET A 600
ALA A 601
MET A 642
 None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
 0.41A 4ltwA-5uc1A:
25.2		 4ltwA-5uc1A:
61.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		3 / 3 LEU A 632
ILE A 555
ARG A 554
 None
 0.67A 4mk4B-5uc1A:
undetectable		 4mk4B-5uc1A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4ojbA-5uc1A:
22.6		 4ojbA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.83A 4ok1A-5uc1A:
23.2		 4ok1A-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
LEU A 562
GLY A 563
GLN A 566
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
 0.46A 4ok1A-5uc1A:
23.2		 4ok1A-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.80A 4okbA-5uc1A:
22.5		 4okbA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.98A 4oktA-5uc1A:
22.9		 4oktA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
LEU A 562
GLY A 563
GLN A 566
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.70A 4oktA-5uc1A:
22.9		 4oktA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4okwA-5uc1A:
22.7		 4okwA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4okxA-5uc1A:
22.5		 4okxA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.81A 4olmA-5uc1A:
22.2		 4olmA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
LEU A 562
GLY A 563
GLN A 566
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
 0.81A 4olmA-5uc1A:
22.2		 4olmA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
LEU A 604
ARG A 607
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.96A 4p6xA-5uc1A:
26.4		 4p6xA-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.86A 4p6xA-5uc1A:
26.4		 4p6xA-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
LEU A 559
ASN A 560
GLY A 563
GLN A 566
GLN A 638
 None
486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-4.6A)
 0.89A 4p6xA-5uc1A:
26.4		 4p6xA-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 11 ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.88A 4p6xC-5uc1A:
26.6		 4p6xC-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 11 LEU A 562
GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.92A 4p6xC-5uc1A:
26.6		 4p6xC-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 11 MET A 556
ASN A 560
LEU A 562
GLN A 566
MET A 600
ARG A 607
GLN A 638
 None
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.78A 4p6xC-5uc1A:
26.6		 4p6xC-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
LEU A 604
ARG A 607
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.86A 4p6xE-5uc1A:
26.3		 4p6xE-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.90A 4p6xE-5uc1A:
26.3		 4p6xE-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
LEU A 604
ARG A 607
GLN A 638
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.64A 4p6xG-5uc1A:
26.7		 4p6xG-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.73A 4p6xG-5uc1A:
26.7		 4p6xG-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.75A 4p6xG-5uc1A:
26.7		 4p6xG-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
LEU A 604
ARG A 607
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.86A 4p6xI-5uc1A:
26.8		 4p6xI-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 4p6xI-5uc1A:
26.8		 4p6xI-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.78A 4p6xK-5uc1A:
26.7		 4p6xK-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.81A 4p6xK-5uc1A:
26.7		 4p6xK-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
ARG A 607
GLN A 638
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 0.54A 4p6xK-5uc1A:
26.7		 4p6xK-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.92A 4udaA-5uc1A:
23.5		 4udaA-5uc1A:
53.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.73A 4udcA-5uc1A:
26.8		 4udcA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 None
486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.90A 4udcA-5uc1A:
26.8		 4udcA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		10 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 635
GLN A 638
CYH A 639
MET A 642
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 (-4.6A)
486  A 801 ( 3.9A)
486  A 801 ( 3.8A)
 0.83A 5nfpA-5uc1A:
26.7		 5nfpA-5uc1A:
81.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.80A 5toaA-5uc1A:
22.9		 5toaA-5uc1A:
16.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		9 / 12 ASN A 560
GLY A 563
GLN A 566
TRP A 596
MET A 600
ARG A 607
PHE A 619
MET A 635
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.67A 5uc3A-5uc1A:
28.2		 5uc3A-5uc1A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 LEU A 559
LEU A 562
MET A 597
GLN A 638
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 0.98A 5uc3A-5uc1A:
28.2		 5uc3A-5uc1A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 GLY A 563
GLN A 566
VAL A 567
TRP A 596
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.67A 5uc3B-5uc1A:
28.2		 5uc3B-5uc1A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
GLY A 563
GLN A 566
VAL A 567
ARG A 607
PHE A 619
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 (-4.6A)
 0.71A 5uc3B-5uc1A:
28.2		 5uc3B-5uc1A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
GLY A 563
GLN A 566
VAL A 567
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.54A 5uc3B-5uc1A:
28.2		 5uc3B-5uc1A:
96.25