SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 ILE A 213
GLY A 363
GLY A 255
ALA A 259
LEU A 343
 None
 1.11A 1i9gA-5uc7A:
undetectable		 1i9gA-5uc7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 11 ALA A 320
LEU A 108
ALA A 109
ALA A 115
THR A 280
 None
 1.04A 1jinA-5uc7A:
undetectable		 1jinA-5uc7A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 8 ASP A 156
PHE A 140
ASN A 142
LEU A 197
 None
 1.05A 1lhvA-5uc7A:
undetectable		 1lhvA-5uc7A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 PHE A 149
GLY A 150
ALA A 170
VAL A 114
SER A 113
 None
None
None
None
LLP  A 274 ( 2.7A)
 1.12A 1sg9C-5uc7A:
2.7		 1sg9C-5uc7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 5 LEU A  37
ASP A  47
GLY A 279
ALA A  32
 None
None
LLP  A 274 ( 4.1A)
None
 0.94A 2aohA-5uc7A:
undetectable		 2aohA-5uc7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		3 / 3 SER A 111
ASP A 147
CYH A 155
 LLP  A 274 ( 4.1A)
None
None
 1.11A 2br4E-5uc7A:
2.4		 2br4E-5uc7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 9 LEU A 257
PHE A 258
LEU A 327
HIS A  57
LEU A 324
 None
 1.38A 2bxeA-5uc7A:
undetectable		 2bxeA-5uc7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 9 LEU A 257
PHE A 258
LEU A 327
LEU A 324
ALA A 275
 None
None
None
None
LLP  A 274 ( 3.7A)
 1.35A 2bxeA-5uc7A:
undetectable		 2bxeA-5uc7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 11 LEU A 108
VAL A 319
ALA A 318
LEU A 315
LEU A 283
 None
 1.31A 2c12F-5uc7A:
undetectable		 2c12F-5uc7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 7 HIS A  57
ASN A  65
THR A 277
GLY A 278
 None
None
LLP  A 274 ( 4.3A)
None
 0.99A 2f6dA-5uc7A:
undetectable		 2f6dA-5uc7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		3 / 3 ARG A 422
VAL A 374
THR A 370
 None
 0.71A 2nmzA-5uc7A:
undetectable		 2nmzA-5uc7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 ILE A 296
ALA A 207
THR A 286
PHE A 304
HIS A 306
 None
 1.24A 2qo4A-5uc7A:
undetectable		 2qo4A-5uc7A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 ILE A 296
ALA A 207
THR A 286
PHE A 304
HIS A 306
 None
 1.24A 2qo6A-5uc7A:
undetectable		 2qo6A-5uc7A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 PHE A 258
CYH A 260
LEU A 210
LEU A 272
LEU A 103
 None
 1.28A 3adsA-5uc7A:
undetectable		 3adsA-5uc7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		3 / 3 HIS A 203
GLU A 204
HIS A 201
 None
 0.85A 3ba0A-5uc7A:
undetectable		 3ba0A-5uc7A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 6 VAL A 214
GLN A 179
GLY A 184
ARG A 181
 None
 1.06A 3bjwE-5uc7A:
undetectable		 3bjwE-5uc7A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 PRO A 402
GLY A 366
ARG A 360
VAL A 359
GLU A 369
 None
 1.45A 3jb2A-5uc7A:
undetectable		 3jb2A-5uc7A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 9 ALA A 207
ASP A 268
ILE A 269
VAL A 116
ILE A 243
 None
 1.09A 3nu4A-5uc7A:
undetectable		 3nu4A-5uc7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		3 / 3 HIS A  57
HIS A  61
ILE A 404
 None
 0.84A 3u52A-5uc7A:
undetectable
3u52C-5uc7A:
undetectable		 3u52A-5uc7A:
23.59
3u52C-5uc7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 9 GLY A  48
PRO A 402
GLU A  33
TYR A  59
GLY A  34
 None
 1.37A 4fimA-5uc7A:
undetectable		 4fimA-5uc7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 8 ILE A 209
ILE A 247
MET A 220
GLY A 218
 None
LLP  A 274 ( 3.8A)
None
None
 0.93A 4hdlA-5uc7A:
undetectable		 4hdlA-5uc7A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 LEU A 347
VAL A 367
PHE A 383
PHE A 382
VAL A 390
 None
 1.10A 4ib4A-5uc7A:
undetectable		 4ib4A-5uc7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 ILE A 265
PHE A 251
LEU A  91
LEU A 324
LEU A 103
 None
 1.23A 4j03A-5uc7A:
undetectable		 4j03A-5uc7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 GLU A 188
LEU A 228
LEU A 210
ARG A 221
ARG A 189
 None
 1.25A 5hnxB-5uc7A:
undetectable		 5hnxB-5uc7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		5 / 12 PHE A  80
ILE A 243
ALA A 123
ILE A 296
ALA A 293
 None
 1.18A 5vc0A-5uc7A:
undetectable		 5vc0A-5uc7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 8 ILE A 265
VAL A  96
GLU A 104
SER A 289
 None
None
TAR  A 501 (-3.9A)
None
 1.12A 6fbvC-5uc7A:
undetectable		 6fbvC-5uc7A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE
(environmental
samples) 		4 / 5 GLN A 179
THR A 139
HIS A 145
GLY A 219
 None
 1.11A 6gbnC-5uc7A:
undetectable		 6gbnC-5uc7A:
20.89