SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ucv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_A_CHDA702_0 (FERROCHELATASE)	5ucv	PROBABLE GTP-BINDING PROTEIN ENGB (Neisseria gonorrhoeae)	4 / 7	LEU A 43 PRO A 136 VAL A 192 TRP A 195	None	1.36A	2hrcA-5ucvA: undetectable	2hrcA-5ucvA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_D_RIMD499_1 (MATRIX PROTEIN 2)	5ucv	PROBABLE GTP-BINDING PROTEIN ENGB (Neisseria gonorrhoeae)	4 / 6	ILE A 139 LEU A 141 LEU A 127 ASP A 123	None	1.08A	2rlfA-5ucvA: undetectable 2rlfD-5ucvA: undetectable	2rlfA-5ucvA: 17.11 2rlfD-5ucvA: 17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	5ucv	PROBABLE GTP-BINDING PROTEIN ENGB (Neisseria gonorrhoeae)	5 / 12	ILE A 107 ALA A 201 PHE A 196 LEU A 67 ILE A 26	None	1.00A	4kjjA-5ucvA: undetectable	4kjjA-5ucvA: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDJ_A_SAMA301_0 (MAGNESIUM-PROTOPORPH YRIN O-METHYLTRANSFERASE)	5ucv	PROBABLE GTP-BINDING PROTEIN ENGB (Neisseria gonorrhoeae)	5 / 12	VAL A 137 GLY A 30 ILE A 139 LEU A 119 LEU A 122	None	1.01A	4qdjA-5ucvA: undetectable	4qdjA-5ucvA: 22.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HRC_A_CHDA702_0","FERROCHELATASE","5ucv","PROBABLE GTP-BINDING PROTEIN ENGB","Neisseria gonorrhoeae",4,"LEU A  43;PRO A 136;VAL A 192;TRP A 195","None","1.36A","2hrcA-5ucvA:undetectable","2hrcA-5ucvA:20.55"],["2RLF_D_RIMD499_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","5ucv","PROBABLE GTP-BINDING PROTEIN ENGB","Neisseria gonorrhoeae",4,"ILE A 139;LEU A 141;LEU A 127;ASP A 123","None","1.08A","2rlfA-5ucvA:undetectable;2rlfD-5ucvA:undetectable","2rlfA-5ucvA:17.11;2rlfD-5ucvA:17.11"],["4KJJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","5ucv","PROBABLE GTP-BINDING PROTEIN ENGB","Neisseria gonorrhoeae",5,"ILE A 107;ALA A 201;PHE A 196;LEU A  67;ILE A  26","None","1.00A","4kjjA-5ucvA:undetectable","4kjjA-5ucvA:22.32"],["4QDJ_A_SAMA301_0","MAGNESIUM-PROTOPORPHYRIN O-METHYLTRANSFERASE","5ucv","PROBABLE GTP-BINDING PROTEIN ENGB","Neisseria gonorrhoeae",5,"VAL A 137;GLY A  30;ILE A 139;LEU A 119;LEU A 122","None","1.01A","4qdjA-5ucvA:undetectable","4qdjA-5ucvA:22.39"]]