SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ud0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 8 HIS A  83
GLU A 134
HIS A 180
ALA A 173
 ZN  A 402 (-3.4A)
ZN  A 402 (-1.9A)
ZN  A 402 (-3.0A)
None
 0.94A 2bnnA-5ud0A:
undetectable
2bnnB-5ud0A:
undetectable		 2bnnA-5ud0A:
undetectable
2bnnB-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 12 GLY A  84
GLY A  51
THR A  85
ILE A 103
ASP A  82
 None
None
None
None
NA  A 401 (-3.8A)
 0.96A 2oxtA-5ud0A:
undetectable		 2oxtA-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 12 GLY A  84
GLY A  51
THR A  85
ILE A 103
ASP A  82
 None
None
None
None
NA  A 401 (-3.8A)
 0.97A 2oxtC-5ud0A:
undetectable		 2oxtC-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 10 VAL A 293
SER A 213
ASN A 253
VAL A 252
GLY A  20
 None
None
NA  A 401 (-3.5A)
None
None
 1.30A 2x2iD-5ud0A:
9.1		 2x2iD-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 12 TYR A 171
VAL A 208
ILE A 249
ALA A  78
SER A 100
 None
 1.34A 3apwA-5ud0A:
undetectable		 3apwA-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 4 VAL A  19
PHE A  22
PHE A  24
VAL A  65
 None
 1.24A 3rv5C-5ud0A:
undetectable
3rv5D-5ud0A:
undetectable		 3rv5C-5ud0A:
undetectable
3rv5D-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 12 ILE A  33
SER A 303
VAL A 245
ILE A   8
LEU A   9
 None
 1.14A 3w68B-5ud0A:
undetectable		 3w68B-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 4 HIS A 108
GLU A 134
HIS A  83
LEU A  81
 None
ZN  A 402 (-1.9A)
ZN  A 402 (-3.4A)
None
 1.37A 4m2rA-5ud0A:
undetectable		 4m2rA-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 12 GLN A  47
ALA A  52
ILE A  53
LEU A  79
GLY A  97
 NA  A 401 (-3.8A)
None
None
None
None
 1.21A 4r38D-5ud0A:
undetectable		 4r38D-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 5 GLU A 161
THR A 203
THR A 117
HIS A 107
 None
 1.30A 5axaA-5ud0A:
undetectable		 5axaA-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 5 GLU A 161
THR A 203
THR A 117
HIS A 108
 None
 1.12A 5axaA-5ud0A:
undetectable		 5axaA-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 5 GLU A 161
THR A 203
THR A 117
HIS A 107
 None
 1.30A 5axaC-5ud0A:
undetectable		 5axaC-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 5 GLU A 161
THR A 203
THR A 117
HIS A 108
 None
 1.12A 5axaC-5ud0A:
undetectable		 5axaC-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 7 SER A 167
ASP A 104
GLY A 136
THR A 178
 None
ZN  A 402 ( 4.4A)
None
None
 1.03A 5btfA-5ud0A:
undetectable
5btfC-5ud0A:
undetectable
5btfD-5ud0A:
undetectable		 5btfA-5ud0A:
undetectable
5btfC-5ud0A:
undetectable
5btfD-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		4 / 6 SER A 106
ALA A 105
MET A 102
LEU A 135
 None
None
NA  A 401 (-3.6A)
None
 1.25A 5dzkB-5ud0A:
undetectable
5dzkP-5ud0A:
undetectable		 5dzkB-5ud0A:
undetectable
5dzkP-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		5 / 9 LEU A  44
GLY A  63
ILE A  67
VAL A  77
ILE A  46
 None
 1.17A 5kr2D-5ud0A:
undetectable		 5kr2D-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		3 / 3 HIS A 125
SER A 130
LYS A   4
 None
 1.41A 5os7A-5ud0A:
undetectable		 5os7A-5ud0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ud0 FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Helicobacter
pylori) 		3 / 3 HIS A 125
SER A 130
LYS A   4
 None
 1.41A 6gmdB-5ud0A:
undetectable		 6gmdB-5ud0A:
undetectable