SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ud6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 10 GLU A  57
ARG A 281
GLU A  65
LEU A  69
ALA A  52
 None
None
None
None
CA  A 401 (-3.9A)
 1.31A 1mjqC-5ud6A:
undetectable
1mjqD-5ud6A:
undetectable		 1mjqC-5ud6A:
undetectable
1mjqD-5ud6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		4 / 4 LEU A 108
VAL A  84
CYH A  82
ALA A  42
 None
 1.26A 1mz9E-5ud6A:
undetectable		 1mz9E-5ud6A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		4 / 5 SER A 217
VAL A  14
VAL A 218
SER A  46
 None
 1.33A 2j9cA-5ud6A:
undetectable
2j9cB-5ud6A:
undetectable
2j9cC-5ud6A:
undetectable		 2j9cA-5ud6A:
undetectable
2j9cB-5ud6A:
undetectable
2j9cC-5ud6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 11 TYR A 145
PHE A 258
ASN A 262
GLY A 149
ILE A 147
 KPI  A 174 ( 3.7A)
None
None
None
None
 1.50A 2zmaA-5ud6A:
undetectable		 2zmaA-5ud6A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 9 ASP A 201
THR A  16
TYR A 145
GLY A 199
ASP A 200
 None
None
KPI  A 174 ( 3.7A)
KPI  A 174 ( 3.8A)
None
 1.35A 3sfuA-5ud6A:
undetectable		 3sfuA-5ud6A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 9 SER A 220
SER A 217
GLY A 214
THR A 204
ASP A  47
 None
 1.46A 4fxsA-5ud6A:
5.9		 4fxsA-5ud6A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 10 ALA A 268
ASP A 286
LEU A 295
LEU A 257
ALA A 256
 None
 1.22A 4zbrA-5ud6A:
undetectable		 4zbrA-5ud6A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 5ud6 DIHYDRODIPICOLINATE
SYNTHASE
(Cyanidioschyzon
merolae) 		5 / 12 MET A 299
LEU A 295
VAL A 277
ASP A 286
THR A 280
 None
 1.18A 5vlmD-5ud6A:
0.3		 5vlmD-5ud6A:
undetectable