SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5udf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 11 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.03A 1dhiB-5udfA:
undetectable		 1dhiB-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.01A 1dhjB-5udfA:
undetectable		 1dhjB-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.00A 1draA-5udfA:
undetectable		 1draA-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.02A 1draB-5udfA:
undetectable		 1draB-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ILE A 162
PHE A 201
ARG A 230
LEU A 228
ILE A 220
 None
 0.96A 1ra2A-5udfA:
undetectable		 1ra2A-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ILE A 162
PHE A 201
ARG A 230
LEU A 228
ILE A 220
 None
 0.97A 1ra8A-5udfA:
undetectable		 1ra8A-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 GLY A 116
VAL A 180
ILE A 162
GLY A 218
VAL A 217
 None
 0.93A 2avsB-5udfA:
2.5		 2avsB-5udfA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.05A 2drcB-5udfA:
undetectable		 2drcB-5udfA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.04A 3drcB-5udfA:
undetectable		 3drcB-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 11 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.08A 3tqbA-5udfA:
undetectable		 3tqbA-5udfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.03A 4dfrB-5udfA:
undetectable		 4dfrB-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.01A 4ej1A-5udfA:
undetectable		 4ej1A-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ILE A 162
PHE A 201
ARG A 230
LEU A 228
ILE A 220
 None
 0.98A 4ej1A-5udfA:
undetectable		 4ej1A-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.01A 4fhbA-5udfA:
undetectable		 4fhbA-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.07A 4nx6A-5udfA:
undetectable		 4nx6A-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.03A 4nx7A-5udfA:
undetectable		 4nx7A-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.03A 4p3rA-5udfA:
undetectable		 4p3rA-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ALA A 225
LEU A 184
ILE A 127
LEU A 118
ILE A 162
 None
 1.05A 4pstA-5udfA:
undetectable		 4pstA-5udfA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ILE A 162
PHE A 201
ARG A 230
LEU A 228
ILE A 220
 None
 0.90A 5eajA-5udfA:
undetectable		 5eajA-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		4 / 5 THR A  82
ALA A  81
THR A 266
TYR A 270
 None
 1.24A 5ecmA-5udfA:
undetectable		 5ecmA-5udfA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		4 / 5 THR A  82
ALA A 265
THR A 266
TYR A 270
 None
 1.32A 5ecmA-5udfA:
undetectable		 5ecmA-5udfA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 ILE A 162
PHE A 201
ARG A 230
LEU A 228
ILE A 220
 None
 0.89A 5ujxA-5udfA:
undetectable		 5ujxA-5udfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 12 LEU A 182
GLY A 126
ALA A 125
LEU A 174
LEU A 164
 None
 1.31A 5x23A-5udfA:
undetectable		 5x23A-5udfA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		5 / 10 VAL A  99
LEU A  89
GLY A 107
GLY A 237
VAL A  83
 None
 1.08A 6eu9B-5udfA:
undetectable		 6eu9B-5udfA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 5udf LIPOPROTEIN-RELEASIN
G SYSTEM
TRANSMEMBRANE
PROTEIN LOLE
(Acinetobacter
baumannii) 		4 / 5 SER A 141
VAL A 140
ASN A 139
PRO A 134
 None
 1.12A 6fi4A-5udfA:
undetectable
6fi4B-5udfA:
undetectable		 6fi4A-5udfA:
19.69
6fi4B-5udfA:
10.00