SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5udg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE
(Bacillus
subtilis) 		3 / 3 PRO A 113
MET A 111
TYR A  70
 None
 0.99A 4qa0B-5udgA:
undetectable		 4qa0B-5udgA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE
(Bacillus
subtilis) 		3 / 3 PRO A 113
MET A 111
TYR A  70
 None
 0.99A 4qa0A-5udgA:
undetectable		 4qa0A-5udgA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE
(Bacillus
subtilis) 		4 / 8 ILE A  66
PHE A 122
THR A 134
PRO A 132
 None
 1.06A 5x23A-5udgA:
undetectable		 5x23A-5udgA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE
(Bacillus
subtilis) 		4 / 8 PHE A  51
PHE A 122
THR A 134
PRO A 132
 None
 1.09A 5x23A-5udgA:
undetectable		 5x23A-5udgA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE
(Bacillus
subtilis) 		4 / 5 ASP A 106
ILE A  66
PHE A  51
TYR A  25
 MG  A 202 (-3.3A)
None
None
None
 1.11A 6a93B-5udgA:
undetectable		 6a93B-5udgA:
18.92