SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uds'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.11A 1l5qA-5udsA:
undetectable		 1l5qA-5udsA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.11A 1l5qB-5udsA:
2.1		 1l5qB-5udsA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.10A 1l7xA-5udsA:
2.4		 1l7xA-5udsA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.08A 1l7xB-5udsA:
undetectable		 1l7xB-5udsA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 5 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.15A 3bcrA-5udsA:
3.3		 3bcrA-5udsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.11A 3dd1A-5udsA:
undetectable		 3dd1A-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.14A 3dd1B-5udsA:
undetectable		 3dd1B-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.13A 3ddsA-5udsA:
2.5		 3ddsA-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.12A 3ddsB-5udsA:
2.4		 3ddsB-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.13A 3ddwA-5udsA:
undetectable		 3ddwA-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 6 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.13A 3ddwB-5udsA:
undetectable		 3ddwB-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		3 / 3 ARG A 259
PHE A 258
PRO A 225
 PO4  A 503 (-2.9A)
None
None
 0.72A 3zoaB-5udsA:
undetectable		 3zoaB-5udsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		3 / 3 ASP A  86
HIS A  88
LYS A  90
 None
 0.98A 4qzuD-5udsA:
undetectable		 4qzuD-5udsA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE
(Lactobacillus
plantarum) 		4 / 8 GLN A 242
VAL A 239
ILE A 222
THR A 252
 None
 1.06A 6cduG-5udsA:
undetectable
6cduH-5udsA:
undetectable		 6cduG-5udsA:
21.28
6cduH-5udsA:
21.28