SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5udy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 VAL A 191
VAL A  36
TRP A 127
 None
 0.94A 1bdwA-5udyA:
undetectable
1bdwB-5udyA:
undetectable		 1bdwA-5udyA:
5.17
1bdwB-5udyA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 8 ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
 1.38A 1ceaA-5udyA:
undetectable
1ceaB-5udyA:
undetectable		 1ceaA-5udyA:
13.51
1ceaB-5udyA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 7 ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
 1.44A 1ceaB-5udyA:
undetectable		 1ceaB-5udyA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 7 ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
 1.45A 1cebA-5udyA:
undetectable		 1cebA-5udyA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 7 ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
 1.39A 1cebB-5udyA:
undetectable		 1cebB-5udyA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 5 THR A  75
ASP A 199
HIS A 203
HIS A 247
HIS A 353
 ZN  A 501 (-2.6A)
ZN  A 502 (-2.3A)
ZN  A 502 (-3.3A)
ZN  A 501 (-3.1A)
ZN  A 502 (-3.3A)
 0.48A 1ei6A-5udyA:
28.9		 1ei6A-5udyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		6 / 8 ASP A  39
THR A  75
ASP A 199
HIS A 203
HIS A 247
HIS A 353
 ZN  A 501 (-2.0A)
ZN  A 501 (-2.6A)
ZN  A 502 (-2.3A)
ZN  A 502 (-3.3A)
ZN  A 501 (-3.1A)
ZN  A 502 (-3.3A)
 0.43A 1ei6C-5udyA:
28.9		 1ei6C-5udyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 8 THR A  75
ASP A 199
HIS A 203
HIS A 353
 ZN  A 501 (-2.6A)
ZN  A 502 (-2.3A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
 0.43A 1ei6D-5udyA:
28.5		 1ei6D-5udyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 9 LEU A 395
GLY A 134
VAL A 398
ILE A 128
ILE A 397
 None
 0.95A 1hpvA-5udyA:
undetectable		 1hpvA-5udyA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		6 / 12 HIS A 203
GLY A 351
GLY A 206
GLY A 202
VAL A 252
GLY A 354
 ZN  A 502 (-3.3A)
None
None
None
None
IOD  A 532 ( 4.3A)
 1.41A 1n2xB-5udyA:
undetectable		 1n2xB-5udyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		6 / 12 HIS A 203
THR A 250
GLY A 351
GLY A 206
GLY A 202
GLY A 354
 ZN  A 502 (-3.3A)
None
None
None
None
IOD  A 532 ( 4.3A)
 1.23A 1n2xB-5udyA:
undetectable		 1n2xB-5udyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 ASP A 279
GLY A 342
VAL A 346
LEU A 300
PHE A 270
 None
 1.32A 1nw3A-5udyA:
undetectable		 1nw3A-5udyA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 THR A 129
PRO A 399
TYR A 388
 None
 0.86A 2dxrA-5udyA:
undetectable		 2dxrA-5udyA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 ARG A 227
GLY A 370
PRO A 371
 None
 0.64A 2hreD-5udyA:
undetectable		 2hreD-5udyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 VAL A  62
ILE A 242
THR A 244
LEU A  35
LEU A 413
 None
None
None
None
IOD  A 521 ( 4.6A)
 1.20A 2jn3A-5udyA:
undetectable		 2jn3A-5udyA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 ASN A  90
HIS A  91
VAL A  94
 None
 0.88A 3elzB-5udyA:
undetectable		 3elzB-5udyA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 7 THR A  75
ASP A 199
HIS A 203
HIS A 353
 ZN  A 501 (-2.6A)
ZN  A 502 (-2.3A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.3A)
 0.39A 3t01A-5udyA:
29.0		 3t01A-5udyA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 8 THR A  84
GLY A 144
PHE A  80
SER A 139
 None
 1.10A 3tzfB-5udyA:
undetectable		 3tzfB-5udyA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 7 TYR A 194
VAL A  36
ILE A 243
GLU A 171
 None
None
None
FUC  A 508 ( 4.3A)
 0.99A 4a97E-5udyA:
undetectable		 4a97E-5udyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 8 TYR A 194
VAL A  36
ILE A 243
GLU A 171
 None
None
None
FUC  A 508 ( 4.3A)
 0.93A 4a97C-5udyA:
undetectable		 4a97C-5udyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 8 TYR A 194
VAL A  36
ILE A 243
GLU A 171
 None
None
None
FUC  A 508 ( 4.3A)
 1.00A 4a97G-5udyA:
undetectable		 4a97G-5udyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ABZ_A_T1CA1209_1
(TETRACYCLINE
REPRESSOR CLASS D)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 HIS A  79
HIS A 247
ARG A 212
PRO A 198
LEU A  54
 None
ZN  A 501 (-3.1A)
None
None
None
 1.48A 4abzA-5udyA:
0.8		 4abzA-5udyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 6 GLU A 352
GLN A 347
HIS A 308
ASN A 283
 IOD  A 532 ( 4.8A)
None
None
None
 1.33A 4pfjB-5udyA:
undetectable		 4pfjB-5udyA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 ASP A 187
ASP A 189
ASN A  31
 None
 0.68A 4q5mA-5udyA:
undetectable		 4q5mA-5udyA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		4 / 5 GLY A 281
TYR A 333
SER A 334
GLU A 352
 None
None
None
IOD  A 532 ( 4.8A)
 1.16A 4xueA-5udyA:
undetectable		 4xueA-5udyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		3 / 3 MET A  74
HIS A  95
GLY A 281
 IOD  A 532 ( 4.6A)
None
None
 0.63A 5gwzB-5udyA:
undetectable		 5gwzB-5udyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
 1.14A 5iqbA-5udyA:
0.0		 5iqbA-5udyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
 1.15A 5iqbD-5udyA:
0.7		 5iqbD-5udyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 11 ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
 1.17A 5iqeA-5udyA:
0.6		 5iqeA-5udyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
 1.18A 5iqeC-5udyA:
0.6		 5iqeC-5udyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens) 		5 / 12 ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
 1.19A 5iqeD-5udyA:
undetectable		 5iqeD-5udyA:
19.76