SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ue0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		4 / 6 LEU A 558
LEU A 639
LEU A 548
LEU A 515
 None
 0.91A 1errA-5ue0A:
undetectable		 1errA-5ue0A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 11 LEU A 465
GLY A 485
LEU A 639
LEU A 548
LEU A 515
 None
 1.05A 1mx1A-5ue0A:
undetectable		 1mx1A-5ue0A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 12 PHE A 605
LEU A 482
PHE A 646
ALA A 537
ALA A 538
 None
 1.31A 1q23A-5ue0A:
undetectable
1q23B-5ue0A:
undetectable		 1q23A-5ue0A:
15.15
1q23B-5ue0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		4 / 7 LEU A 482
PHE A 646
ILE A 541
GLY A 485
 None
 0.87A 2v0mC-5ue0A:
undetectable		 2v0mC-5ue0A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 11 THR A 473
LEU A 555
VAL A 551
SER A 534
ILE A 541
 None
 1.20A 2zbzA-5ue0A:
undetectable		 2zbzA-5ue0A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 12 MET A 437
GLN A 459
ALA A 444
GLY A 456
LEU A 492
 None
 1.40A 3aodC-5ue0A:
2.5		 3aodC-5ue0A:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 11 VAL A 542
ALA A 537
SER A 644
LEU A 482
VAL A 551
 None
 1.43A 4eilA-5ue0A:
undetectable		 4eilA-5ue0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 10 VAL A 542
ALA A 537
SER A 644
LEU A 482
VAL A 551
 None
 1.34A 4eilB-5ue0A:
undetectable		 4eilB-5ue0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		4 / 8 GLU A 376
GLN A 369
GLY A 370
SER A 373
 None
 0.88A 4f93B-5ue0A:
undetectable		 4f93B-5ue0A:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.91A 4k8cA-5ue0A:
undetectable		 4k8cA-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.92A 4kahA-5ue0A:
undetectable		 4kahA-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.92A 4kahB-5ue0A:
undetectable		 4kahB-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.91A 4kanA-5ue0A:
undetectable		 4kanA-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.91A 4kanB-5ue0A:
undetectable		 4kanB-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.91A 4kbeA-5ue0A:
undetectable		 4kbeA-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.96A 4kbeB-5ue0A:
undetectable		 4kbeB-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 11 VAL A 542
ALA A 537
SER A 644
LEU A 482
VAL A 551
 None
 1.39A 4kyaG-5ue0A:
undetectable		 4kyaG-5ue0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.89A 4lbgA-5ue0A:
undetectable		 4lbgA-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 SER A 471
TYR A 478
PRO A 383
 None
 0.90A 4lbgB-5ue0A:
undetectable		 4lbgB-5ue0A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		4 / 4 THR A 397
GLY A 405
ASP A 407
SER A 400
 None
 1.31A 4rfqA-5ue0A:
undetectable		 4rfqA-5ue0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		3 / 3 VAL A 380
TYR A 466
ALA A 469
 None
 0.50A 4ybnA-5ue0A:
undetectable		 4ybnA-5ue0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 12 LEU A 396
LEU A 403
VAL A 440
ALA A 443
LEU A 356
 None
 1.09A 5jvzA-5ue0A:
undetectable		 5jvzA-5ue0A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ue0 CT622 PROTEIN
(Chlamydia
trachomatis) 		5 / 9 LEU A 580
SER A 560
LEU A 609
ARG A 611
GLN A 608
 MLY  A 579 ( 4.6A)
None
None
None
None
 1.44A 5o96E-5ue0A:
undetectable
5o96F-5ue0A:
undetectable		 5o96E-5ue0A:
undetectable
5o96F-5ue0A:
undetectable