SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ue2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5ue2 MATRILYSIN
(Homo
sapiens) 		5 / 12 ARG A 177
GLY A 185
PRO A  65
LEU A 156
ALA A 191
 None
 1.03A 1gseB-5ue2A:
undetectable		 1gseB-5ue2A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5ue2 MATRILYSIN
(Homo
sapiens) 		4 / 7 GLN A  63
ALA A   4
ARG A  57
ASN A  55
 None
 1.07A 1t9wA-5ue2A:
undetectable		 1t9wA-5ue2A:
12.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 5ue2 MATRILYSIN
(Homo
sapiens) 		3 / 3 HIS A 194
HIS A 198
HIS A 204
 ZN  A 304 (-3.3A)
ZN  A 304 (-3.3A)
ZN  A 304 (-3.2A)
 0.37A 2ozrF-5ue2A:
20.3		 2ozrF-5ue2A:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 5ue2 MATRILYSIN
(Homo
sapiens) 		4 / 6 HIS A 198
HIS A 204
HIS A 194
ASP A 230
 ZN  A 304 (-3.3A)
ZN  A 304 (-3.2A)
ZN  A 304 (-3.3A)
None
 1.18A 3nvcA-5ue2A:
undetectable		 3nvcA-5ue2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5ue2 MATRILYSIN
(Homo
sapiens) 		5 / 12 HIS A 158
HIS A 171
GLY A 137
ASP A 145
GLY A 141
 ZN  A 303 (-3.3A)
ZN  A 303 (-3.5A)
None
ZN  A 303 (-2.7A)
None
 1.32A 4qa2A-5ue2A:
undetectable		 4qa2A-5ue2A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5ue2 MATRILYSIN
(Homo
sapiens) 		4 / 6 GLU A 176
GLY A 153
PHE A  22
ARG A  21
 CA  A 302 (-3.4A)
CA  A 302 (-4.5A)
None
SGN  A 305 (-3.5A)
 1.34A 5jcnB-5ue2A:
undetectable		 5jcnB-5ue2A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 5ue2 MATRILYSIN
(Homo
sapiens) 		3 / 3 HIS A 158
ASP A 145
HIS A 143
 ZN  A 303 (-3.3A)
ZN  A 303 (-2.7A)
ZN  A 303 (-3.4A)
 0.73A 5oexA-5ue2A:
undetectable		 5oexA-5ue2A:
19.03