SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 PHE B 141
LEU B 126
LEU B 133
LEU B 157
PRO B 161
 None
 1.48A 1p33A-5uf1B:
undetectable		 1p33A-5uf1B:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 LEU B 126
LEU B 102
LEU B  78
LEU B 112
LEU B 109
 None
 1.04A 1sqnB-5uf1B:
undetectable		 1sqnB-5uf1B:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 PHE B  93
ILE B  47
LEU B  64
LEU B  80
LEU B  56
 None
 1.31A 4xumA-5uf1B:
undetectable		 4xumA-5uf1B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 ALA B  45
LEU B  40
ILE B  61
VAL B  68
PHE B  69
 None
 1.14A 5vlmB-5uf1B:
undetectable		 5vlmB-5uf1B:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 ALA B  45
LEU B  40
ILE B  61
VAL B  68
PHE B  69
 None
 1.15A 5vlmE-5uf1B:
undetectable		 5vlmE-5uf1B:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5uf1 O13
(Petromyzon
marinus) 		5 / 12 ALA B  45
LEU B  40
ILE B  61
VAL B  68
PHE B  69
 None
 1.31A 5vlmG-5uf1B:
undetectable		 5vlmG-5uf1B:
21.51