SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 153
MET A 151
LEU A 175
VAL A 134
MET A 183
 None
None
EDO  A 309 (-4.4A)
None
None
 1.49A 1a27A-5uf2A:
undetectable		 1a27A-5uf2A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 190
ALA A 136
PRO A 131
LEU A 175
ILE A 187
 None
None
None
EDO  A 309 (-4.4A)
None
 0.94A 2cd2A-5uf2A:
undetectable		 2cd2A-5uf2A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 PHE A  36
ALA A  15
TYR A  80
VAL A 107
LEU A  61
 None
 1.23A 2rctA-5uf2A:
undetectable		 2rctA-5uf2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 9 PHE A 114
ALA A 108
GLY A  83
GLY A  28
ILE A  27
 None
BTB  A 303 (-3.9A)
EDO  A 306 (-3.2A)
None
None
 1.15A 2v7bA-5uf2A:
undetectable		 2v7bA-5uf2A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 9 PHE A 114
ALA A 108
GLY A  83
GLY A  28
ILE A  27
 None
BTB  A 303 (-3.9A)
EDO  A 306 (-3.2A)
None
None
 1.13A 2v7bB-5uf2A:
2.3		 2v7bB-5uf2A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 114
PHE A 199
ALA A 100
SER A  54
TYR A  80
 None
None
NA  A 301 (-3.9A)
None
None
 1.38A 3apwA-5uf2A:
undetectable		 3apwA-5uf2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 10 ALA A 136
ILE A 169
PRO A 131
LEU A 175
ILE A 187
 None
None
None
EDO  A 309 (-4.4A)
None
 1.08A 3hbbA-5uf2A:
undetectable		 3hbbA-5uf2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		4 / 8 VAL A 107
VAL A  69
ILE A  33
GLY A  26
 None
 0.95A 3hjoA-5uf2A:
undetectable		 3hjoA-5uf2A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ALA A  84
ASP A 171
ILE A 169
ASP A  85
PHE A 130
 None
None
None
EDO  A 306 (-3.5A)
None
 1.48A 3w37A-5uf2A:
undetectable		 3w37A-5uf2A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ALA A  84
ASP A 171
ILE A 169
ASP A  85
PHE A 130
 None
None
None
EDO  A 306 (-3.5A)
None
 1.47A 3welA-5uf2A:
undetectable		 3welA-5uf2A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ALA A  84
ASP A 171
ILE A 169
ASP A  85
PHE A 130
 None
None
None
EDO  A 306 (-3.5A)
None
 1.49A 3weoA-5uf2A:
undetectable		 3weoA-5uf2A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		7 / 12 ILE A 190
ALA A 136
ILE A 169
ARG A 158
PRO A 131
LEU A 175
ILE A 187
 None
None
None
None
None
EDO  A 309 (-4.4A)
None
 1.45A 4m2xA-5uf2A:
undetectable		 4m2xA-5uf2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 190
ALA A 136
ILE A 169
LEU A 132
PRO A 131
ILE A 187
 None
 1.19A 4m2xC-5uf2A:
undetectable		 4m2xC-5uf2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 190
ALA A 136
ARG A 158
PRO A 131
LEU A 175
ILE A 187
 None
None
None
None
EDO  A 309 (-4.4A)
None
 1.37A 4m2xE-5uf2A:
undetectable		 4m2xE-5uf2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 190
ALA A 136
ILE A 169
PRO A 131
ILE A 187
 None
 0.87A 4m2xG-5uf2A:
undetectable		 4m2xG-5uf2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 190
ALA A 136
SER A 145
LEU A 148
LEU A 132
 None
 1.40A 4qztC-5uf2A:
undetectable		 4qztC-5uf2A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 PHE A  36
ALA A  15
TYR A  80
VAL A 107
LEU A  61
 None
 1.15A 4qzuC-5uf2A:
undetectable		 4qzuC-5uf2A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 197
GLY A  96
GLY A  97
ALA A 200
LEU A 127
 None
NA  A 301 ( 3.5A)
NA  A 301 ( 4.7A)
None
None
 0.78A 5c0oF-5uf2A:
2.4		 5c0oF-5uf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		4 / 8 GLY A 197
ARG A 158
ASP A 171
ASP A  85
 None
None
None
EDO  A 306 (-3.5A)
 0.96A 5vlmB-5uf2A:
undetectable		 5vlmB-5uf2A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		4 / 8 ILE A 169
ARG A 158
VAL A 172
ASP A  85
 None
None
None
EDO  A 306 (-3.5A)
 1.07A 5vlmF-5uf2A:
undetectable		 5vlmF-5uf2A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A
(Neisseria
gonorrhoeae) 		3 / 3 SER A  57
LYS A  56
SER A  54
 None
 0.71A 6az3P-5uf2A:
undetectable		 6az3P-5uf2A:
18.67