SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		4 / 5 ARG A  99
ALA A 103
ASP A  26
GLY A  24
 None
 1.17A 1e7bA-5uf8A:
undetectable		 1e7bA-5uf8A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 GLY A  29
ALA A  27
ILE A  33
VAL A  91
ILE A  89
 GDP  A 500 (-3.2A)
GDP  A 500 (-4.2A)
None
None
None
 0.83A 4ax8A-5uf8A:
undetectable		 4ax8A-5uf8A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 GLY A  29
ALA A  27
ILE A  33
VAL A  91
ILE A  89
 GDP  A 500 (-3.2A)
GDP  A 500 (-4.2A)
None
None
None
 0.85A 4aztA-5uf8A:
undetectable		 4aztA-5uf8A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 ILE A 148
PHE A  82
LEU A 121
VAL A 123
LEU A 107
 None
 1.12A 4g1bD-5uf8A:
3.8		 4g1bD-5uf8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 GLY A  29
ALA A  27
ILE A  33
VAL A  91
ILE A  89
 GDP  A 500 (-3.2A)
GDP  A 500 (-4.2A)
None
None
None
 0.94A 4uw0A-5uf8A:
undetectable		 4uw0A-5uf8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		4 / 6 ARG A  75
GLU A 113
PHE A  82
VAL A  23
 None
 1.15A 5h4dA-5uf8A:
4.6		 5h4dA-5uf8A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		4 / 6 LEU A 111
GLN A 108
LEU A 143
LEU A 145
 None
 1.16A 5yvnA-5uf8A:
undetectable		 5yvnA-5uf8A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 LEU A 121
PRO A 152
ILE A  88
GLY A  87
ASP A 118
 None
 0.80A 6emuB-5uf8A:
4.0		 6emuB-5uf8A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR
(Candida
albicans) 		5 / 12 LEU A 121
PRO A 152
ILE A  88
GLY A  87
ILE A 148
 None
 0.71A 6emuB-5uf8A:
4.0		 6emuB-5uf8A:
21.74