SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ufk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P93_D_DEXD4999_2 (GLUCOCORTICOID RECEPTOR)	5ufk	EFFECTOR PROTEIN SIDK (Legionella pneumophila)	4 / 5	LEU A 183 MET A 155 LEU A 159 GLN A 135	MLY A 180 ( 4.8A) None None None	1.32A	1p93D-5ufkA: undetectable	1p93D-5ufkA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZUC_B_T98B202_1 (PROGESTERONE RECEPTOR)	5ufk	EFFECTOR PROTEIN SIDK (Legionella pneumophila)	5 / 12	LEU A 91 LEU A 88 LEU A 42 LEU A 107 THR A 169	None	1.27A	1zucB-5ufkA: undetectable	1zucB-5ufkA: 26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J26_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	5ufk	EFFECTOR PROTEIN SIDK (Legionella pneumophila)	5 / 12	MET A 115 MET A 103 LEU A 107 ILE A 36 LEU A 94	None	1.21A	4j26A-5ufkA: undetectable	4j26A-5ufkA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J26_B_ESTB600_1 (ESTROGEN RECEPTOR BETA)	5ufk	EFFECTOR PROTEIN SIDK (Legionella pneumophila)	5 / 12	MET A 115 MET A 103 LEU A 107 ILE A 36 LEU A 94	None	1.21A	4j26B-5ufkA: undetectable	4j26B-5ufkA: 20.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P93_D_DEXD4999_2","GLUCOCORTICOID RECEPTOR","5ufk","EFFECTOR PROTEIN SIDK","Legionella pneumophila",4,"LEU A 183;MET A 155;LEU A 159;GLN A 135","MLY A 180 ( 4.8A);None;None;None","1.32A","1p93D-5ufkA:undetectable","1p93D-5ufkA:21.31"],["1ZUC_B_T98B202_1","PROGESTERONE RECEPTOR","5ufk","EFFECTOR PROTEIN SIDK","Legionella pneumophila",5,"LEU A  91;LEU A  88;LEU A  42;LEU A 107;THR A 169","None","1.27A","1zucB-5ufkA:undetectable","1zucB-5ufkA:26.45"],["4J26_A_ESTA600_1","ESTROGEN RECEPTOR BETA","5ufk","EFFECTOR PROTEIN SIDK","Legionella pneumophila",5,"MET A 115;MET A 103;LEU A 107;ILE A  36;LEU A  94","None","1.21A","4j26A-5ufkA:undetectable","4j26A-5ufkA:20.79"],["4J26_B_ESTB600_1","ESTROGEN RECEPTOR BETA","5ufk","EFFECTOR PROTEIN SIDK","Legionella pneumophila",5,"MET A 115;MET A 103;LEU A 107;ILE A  36;LEU A  94","None","1.21A","4j26B-5ufkA:undetectable","4j26B-5ufkA:20.79"]]