SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ufl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		5 / 12 LEU A 288
LEU A 303
ALA A 305
VAL A 255
ILE A 238
 None
 1.01A 2h42C-5uflA:
undetectable		 2h42C-5uflA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 7 ASP A 246
SER A 201
VAL A 204
LEU A 118
 None
 1.04A 2hdnE-5uflA:
undetectable
2hdnF-5uflA:
undetectable
2hdnH-5uflA:
undetectable		 2hdnE-5uflA:
5.78
2hdnF-5uflA:
20.50
2hdnH-5uflA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 7 SER A 201
VAL A 204
LEU A 118
ASP A 246
 None
 1.00A 2hdnF-5uflA:
undetectable
2hdnG-5uflA:
undetectable
2hdnH-5uflA:
undetectable		 2hdnF-5uflA:
20.50
2hdnG-5uflA:
5.78
2hdnH-5uflA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 7 ILE A 393
PHE A 370
ILE A 369
PHE A 385
 None
 0.93A 2q6hA-5uflA:
undetectable		 2q6hA-5uflA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 7 ILE A 393
PHE A 370
ILE A 369
PHE A 385
 None
 0.93A 2qb4A-5uflA:
3.1		 2qb4A-5uflA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 6 LEU A 237
GLN A 236
PHE A 239
LEU A 209
 None
 0.83A 2zxwP-5uflA:
undetectable
2zxwW-5uflA:
undetectable		 2zxwP-5uflA:
19.09
2zxwW-5uflA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		5 / 12 PHE A 189
SER A 214
LEU A 257
LEU A 197
LEU A 166
 None
 1.26A 3adsA-5uflA:
undetectable		 3adsA-5uflA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 6 LEU A 237
GLN A 236
PHE A 239
LEU A 209
 None
 0.84A 3ag1C-5uflA:
undetectable
3ag1J-5uflA:
undetectable		 3ag1C-5uflA:
19.09
3ag1J-5uflA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 8 SER A 296
ASP A 292
ASP A 246
TYR A 129
 None
 1.26A 3havA-5uflA:
undetectable		 3havA-5uflA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		5 / 7 ILE A 238
ILE A 241
VAL A 206
LEU A 209
SER A 210
 None
 1.09A 3r9vA-5uflA:
undetectable
3r9vB-5uflA:
undetectable		 3r9vA-5uflA:
19.96
3r9vB-5uflA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 6 LEU A 257
PHE A 226
THR A 216
LEU A 197
 None
 1.02A 3t3zD-5uflA:
undetectable		 3t3zD-5uflA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		4 / 8 ASP A 114
PHE A 146
VAL A 107
LEU A 158
 None
 1.07A 4f5zA-5uflA:
undetectable		 4f5zA-5uflA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		5 / 12 ILE A 238
LEU A 237
ALA A 208
SER A 210
LEU A 257
 None
 1.36A 4m11C-5uflA:
2.0		 4m11C-5uflA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5ufl PROTEIN CIP2A
(Homo
sapiens) 		5 / 12 ILE A 393
ILE A 374
PHE A 321
PHE A 385
MET A 320
 None
 1.07A 6j20A-5uflA:
undetectable		 6j20A-5uflA:
21.08