SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ufv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 THR A  74
LEU A 131
GLY A 134
LYS A   2
 HIC  A   1 (-3.7A)
None
None
HIC  A   1 ( 3.6A)
 0.89A 1gtiD-5ufvA:
undetectable		 1gtiD-5ufvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 THR A  74
LEU A 131
GLY A 134
LYS A   2
 HIC  A   1 (-3.7A)
None
None
HIC  A   1 ( 3.6A)
 0.89A 1gtiE-5ufvA:
undetectable		 1gtiE-5ufvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 5 THR A  74
LEU A 131
GLY A 133
LYS A   2
 HIC  A   1 (-3.7A)
None
None
HIC  A   1 ( 3.6A)
 1.37A 1gtiF-5ufvA:
undetectable		 1gtiF-5ufvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 5 THR A  74
LEU A 131
GLY A 134
LYS A   2
 HIC  A   1 (-3.7A)
None
None
HIC  A   1 ( 3.6A)
 0.93A 1gtiF-5ufvA:
undetectable		 1gtiF-5ufvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.72A 1usqA-5ufvA:
undetectable		 1usqA-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.74A 1usqB-5ufvA:
undetectable		 1usqB-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.73A 1usqC-5ufvA:
undetectable		 1usqC-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.73A 1usqD-5ufvA:
undetectable		 1usqD-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.73A 1usqE-5ufvA:
undetectable		 1usqE-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.80A 2jkjA-5ufvA:
undetectable		 2jkjA-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.80A 2jkjB-5ufvA:
undetectable		 2jkjB-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.80A 2jkjC-5ufvA:
undetectable		 2jkjC-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.75A 2jklB-5ufvA:
undetectable		 2jklB-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 TYR A 196
GLU A 156
TYR A 217
TRP A 126
 None
 1.49A 3cotA-5ufvA:
undetectable		 3cotA-5ufvA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		5 / 10 ILE A 204
GLY A 195
VAL A  38
LEU A  81
ARG A 154
 None
 1.25A 3elzC-5ufvA:
undetectable		 3elzC-5ufvA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		5 / 12 ILE A 158
GLY A  78
ALA A 129
ILE A  80
ALA A 107
 None
 1.02A 3jb1A-5ufvA:
undetectable		 3jb1A-5ufvA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 8 PHE A 109
THR A 120
TRP A 126
ASP A 119
 None
 0.99A 4drjB-5ufvA:
undetectable		 4drjB-5ufvA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 VAL A 177
PHE A 225
GLY A 145
PHE A 102
 None
 0.95A 4ejjB-5ufvA:
undetectable		 4ejjB-5ufvA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_B_IZPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 VAL A   4
TYR A   7
TRP A  70
HIS A 155
 None
 1.41A 4jtrB-5ufvA:
undetectable		 4jtrB-5ufvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		3 / 3 TYR A 217
GLY A  78
PRO A  79
 None
 0.72A 4qwpA-5ufvA:
undetectable		 4qwpA-5ufvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN
(Thermothelomyces
thermophila) 		4 / 7 GLY A 108
ALA A 107
GLU A 106
SER A 140
 None
 0.85A 4r1zB-5ufvA:
undetectable		 4r1zB-5ufvA:
19.14