SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ugf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 ALA A 216
PHE A 124
ASN A 115
LEU A 271
PHE A 238
 None
None
PO4  A 301 (-4.9A)
None
None
 1.01A 1og5A-5ugfA:
undetectable		 1og5A-5ugfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 ILE A 241
ALA A 216
PHE A 124
ASN A 115
LEU A 271
 None
None
None
PO4  A 301 (-4.9A)
None
 1.16A 1og5B-5ugfA:
undetectable		 1og5B-5ugfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 ILE A 241
PHE A 124
ASN A 115
LEU A 271
PHE A 238
 None
None
PO4  A 301 (-4.9A)
None
None
 1.05A 1og5B-5ugfA:
undetectable		 1og5B-5ugfA:
20.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		10 / 10 GLY A 118
PHE A 200
GLU A 201
VAL A 217
GLY A 218
MET A 219
THR A 242
ASN A 243
VAL A 245
HIS A 257
 IM5  A 308 (-3.7A)
IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-4.3A)
IM5  A 308 (-3.1A)
IM5  A 308 ( 4.5A)
IM5  A 308 (-3.6A)
 0.62A 1pwyE-5ugfA:
44.1		 1pwyE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 GLY A 218
PHE A 200
GLU A 201
GLY A 197
HIS A 257
 IM5  A 308 (-3.4A)
IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
None
IM5  A 308 (-3.6A)
 1.15A 1pwyE-5ugfA:
44.1		 1pwyE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 GLY A 218
PHE A 200
GLY A 197
VAL A 217
HIS A 257
 IM5  A 308 (-3.4A)
IM5  A 308 (-4.6A)
None
IM5  A 308 (-4.4A)
IM5  A 308 (-3.6A)
 1.22A 1pwyE-5ugfA:
44.1		 1pwyE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 PHE A 200
GLU A 201
VAL A 245
GLY A 118
HIS A 257
 IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
IM5  A 308 ( 4.5A)
IM5  A 308 (-3.7A)
IM5  A 308 (-3.6A)
 1.22A 1pwyE-5ugfA:
44.1		 1pwyE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		10 / 10 GLY A 118
PHE A 200
GLU A 201
VAL A 217
GLY A 218
MET A 219
THR A 242
ASN A 243
VAL A 245
HIS A 257
 IM5  A 308 (-3.7A)
IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-4.3A)
IM5  A 308 (-3.1A)
IM5  A 308 ( 4.5A)
IM5  A 308 (-3.6A)
 0.43A 1v3qE-5ugfA:
44.8		 1v3qE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 GLY A 119
GLU A 201
VAL A 217
ASN A 243
VAL A 245
 None
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.1A)
IM5  A 308 ( 4.5A)
 1.32A 1v3qE-5ugfA:
44.8		 1v3qE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 GLY A 218
PHE A 200
GLU A 201
GLY A 197
HIS A 257
 IM5  A 308 (-3.4A)
IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
None
IM5  A 308 (-3.6A)
 1.24A 1v3qE-5ugfA:
44.8		 1v3qE-5ugfA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 10 PHE A 200
GLU A 201
VAL A 245
GLY A 118
HIS A 257
 IM5  A 308 (-4.6A)
IM5  A 308 (-2.9A)
IM5  A 308 ( 4.5A)
IM5  A 308 (-3.7A)
IM5  A 308 (-3.6A)
 1.11A 1v3qE-5ugfA:
44.8		 1v3qE-5ugfA:
99.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 9 LEU A 271
GLY A 264
VAL A 126
ASP A 128
ILE A 241
 None
 1.33A 2a1oB-5ugfA:
undetectable		 2a1oB-5ugfA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 GLU A 224
VAL A  96
LEU A  93
ALA A 228
MET A 162
 None
 1.29A 2jj8C-5ugfA:
undetectable		 2jj8C-5ugfA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.14A 2y69C-5ugfA:
undetectable
2y69J-5ugfA:
undetectable		 2y69C-5ugfA:
24.48
2y69J-5ugfA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.18A 2y69P-5ugfA:
undetectable
2y69W-5ugfA:
undetectable		 2y69P-5ugfA:
24.48
2y69W-5ugfA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.13A 3abmC-5ugfA:
undetectable
3abmJ-5ugfA:
undetectable		 3abmC-5ugfA:
24.48
3abmJ-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.18A 3abmP-5ugfA:
undetectable
3abmW-5ugfA:
undetectable		 3abmP-5ugfA:
24.48
3abmW-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.16A 3ag3C-5ugfA:
undetectable
3ag3J-5ugfA:
undetectable		 3ag3C-5ugfA:
24.48
3ag3J-5ugfA:
11.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 6 GLY A 118
GLU A 201
GLY A 218
MET A 219
ASN A 243
 IM5  A 308 (-3.7A)
IM5  A 308 (-2.9A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-3.1A)
 0.62A 3e9rA-5ugfA:
40.3		 3e9rA-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 6 GLY A 118
GLU A 201
GLY A 218
MET A 219
ASN A 243
 IM5  A 308 (-3.7A)
IM5  A 308 (-2.9A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-3.1A)
 0.66A 3e9rC-5ugfA:
40.6		 3e9rC-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		11 / 12 SER A  33
TYR A  88
ALA A 116
GLY A 118
GLU A 201
VAL A 217
GLY A 218
MET A 219
ASN A 243
HIS A 257
VAL A 260
 PO4  A 301 (-2.8A)
IM5  A 308 (-4.5A)
PO4  A 301 ( 4.0A)
IM5  A 308 (-3.7A)
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-3.1A)
IM5  A 308 (-3.6A)
IM5  A 308 ( 4.3A)
 0.41A 3f8wA-5ugfA:
42.2		 3f8wA-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 HIS A  64
GLY A 118
ASN A 243
HIS A 257
VAL A 260
 PO4  A 301 (-4.5A)
IM5  A 308 (-3.7A)
IM5  A 308 (-3.1A)
IM5  A 308 (-3.6A)
IM5  A 308 ( 4.3A)
 1.15A 3f8wB-5ugfA:
43.7		 3f8wB-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		11 / 12 SER A  33
HIS A  86
TYR A  88
GLY A 118
GLU A 201
VAL A 217
GLY A 218
MET A 219
ASN A 243
HIS A 257
VAL A 260
 PO4  A 301 (-2.8A)
PO4  A 301 (-4.0A)
IM5  A 308 (-4.5A)
IM5  A 308 (-3.7A)
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-3.1A)
IM5  A 308 (-3.6A)
IM5  A 308 ( 4.3A)
 0.40A 3f8wB-5ugfA:
43.7		 3f8wB-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 TYR A  88
VAL A 217
GLY A 218
MET A 219
HIS A  64
 IM5  A 308 (-4.5A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
PO4  A 301 (-4.5A)
 1.41A 3f8wB-5ugfA:
43.7		 3f8wB-5ugfA:
44.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		11 / 12 SER A  33
HIS A  86
TYR A  88
ALA A 116
GLY A 118
GLU A 201
VAL A 217
GLY A 218
MET A 219
ASN A 243
VAL A 260
 PO4  A 301 (-2.8A)
PO4  A 301 (-4.0A)
IM5  A 308 (-4.5A)
PO4  A 301 ( 4.0A)
IM5  A 308 (-3.7A)
IM5  A 308 (-2.9A)
IM5  A 308 (-4.4A)
IM5  A 308 (-3.4A)
IM5  A 308 (-3.5A)
IM5  A 308 (-3.1A)
IM5  A 308 ( 4.3A)
 0.36A 3f8wC-5ugfA:
42.0		 3f8wC-5ugfA:
44.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 GLY A  32
ASN A 243
VAL A 245
GLY A 218
SER A 220
 PO4  A 301 (-3.1A)
IM5  A 308 (-3.1A)
IM5  A 308 ( 4.5A)
IM5  A 308 (-3.4A)
PO4  A 301 (-2.5A)
 1.26A 3k13B-5ugfA:
undetectable		 3k13B-5ugfA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 4 LEU A  35
GLY A  34
GLY A 264
THR A 242
 None
None
None
IM5  A 308 (-4.3A)
 0.79A 3si7A-5ugfA:
undetectable		 3si7A-5ugfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 11 VAL A 102
PHE A 103
ILE A  53
LEU A 106
PHE A  70
 None
 1.06A 3t3rA-5ugfA:
undetectable		 3t3rA-5ugfA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 LEU A  35
GLY A 264
ILE A 241
VAL A 126
 None
 0.84A 3wriA-5ugfA:
undetectable		 3wriA-5ugfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 LEU A  35
GLY A 264
ILE A 241
VAL A 126
 None
 0.84A 3wriB-5ugfA:
undetectable		 3wriB-5ugfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 LEU A  35
GLY A 264
ILE A 241
VAL A 126
 None
 0.83A 3wrkA-5ugfA:
undetectable		 3wrkA-5ugfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 VAL A 113
GLU A 224
LEU A  42
ARG A  84
GLY A  83
 None
None
None
PO4  A 301 (-4.1A)
None
 1.34A 5m50E-5ugfA:
undetectable		 5m50E-5ugfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		3 / 3 CYH A  78
MET A 279
ASN A  74
 None
 1.07A 5qh8A-5ugfA:
undetectable		 5qh8A-5ugfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.12A 5wauC-5ugfA:
undetectable
5wauJ-5ugfA:
undetectable		 5wauC-5ugfA:
24.48
5wauJ-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.08A 5wauc-5ugfA:
undetectable
5wauj-5ugfA:
undetectable		 5wauc-5ugfA:
24.48
5wauj-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PRO A  54
THR A  13
ASN A  12
LYS A  11
 None
 1.22A 5x23A-5ugfA:
undetectable		 5x23A-5ugfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.13A 5xdqC-5ugfA:
undetectable
5xdqJ-5ugfA:
undetectable		 5xdqC-5ugfA:
24.48
5xdqJ-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 5 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.12A 5xdqP-5ugfA:
undetectable
5xdqW-5ugfA:
undetectable		 5xdqP-5ugfA:
24.48
5xdqW-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		5 / 12 GLU A  89
PRO A 198
GLU A 201
THR A 242
GLY A 118
 None
None
IM5  A 308 (-2.9A)
IM5  A 308 (-4.3A)
IM5  A 308 (-3.7A)
 1.12A 5xioA-5ugfA:
undetectable		 5xioA-5ugfA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.09A 5z84P-5ugfA:
undetectable
5z84W-5ugfA:
undetectable		 5z84P-5ugfA:
24.48
5z84W-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.09A 5z85P-5ugfA:
undetectable
5z85W-5ugfA:
undetectable		 5z85P-5ugfA:
24.48
5z85W-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.09A 5z86C-5ugfA:
undetectable
5z86J-5ugfA:
undetectable		 5z86C-5ugfA:
24.48
5z86J-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.08A 5z86P-5ugfA:
undetectable
5z86W-5ugfA:
undetectable		 5z86P-5ugfA:
24.48
5z86W-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.12A 5zcoP-5ugfA:
undetectable
5zcoW-5ugfA:
undetectable		 5zcoP-5ugfA:
24.48
5zcoW-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.09A 5zcpC-5ugfA:
undetectable
5zcpJ-5ugfA:
undetectable		 5zcpC-5ugfA:
24.48
5zcpJ-5ugfA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ugf PURINE NUCLEOSIDE
PHOSPHORYLASE
(Homo
sapiens) 		4 / 6 PHE A  98
PHE A  56
LEU A  68
PHE A  70
 None
 1.12A 5zcpP-5ugfA:
undetectable
5zcpW-5ugfA:
undetectable		 5zcpP-5ugfA:
24.48
5zcpW-5ugfA:
11.64