SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ugj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 4 THR A 133
LEU A 137
VAL A 140
LEU A 144
 None
 0.99A 1fbmB-5ugjA:
undetectable		 1fbmB-5ugjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 GLY A  48
ALA A  34
ASN A  12
ALA A  11
ILE A   8
 None
 1.00A 1likA-5ugjA:
6.1		 1likA-5ugjA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 HIS A 217
ARG A 209
HIS A 156
ASP A 162
 None
 1.15A 3nvcA-5ugjA:
undetectable		 3nvcA-5ugjA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 ILE A   6
LEU A  19
THR A  29
THR A 100
ILE A 120
 None
 1.09A 3prsA-5ugjA:
undetectable		 3prsA-5ugjA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 4 ASP A 105
ASP A 104
GLY A 102
THR A  82
 None
 1.22A 3tl9B-5ugjA:
undetectable		 3tl9B-5ugjA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		5 / 11 ALA A  11
GLU A  36
LEU A  45
GLY A  56
LEU A  31
 None
 1.24A 3uudA-5ugjA:
undetectable		 3uudA-5ugjA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 ALA A 241
MET A  15
THR A 167
PHE A 134
 None
 1.03A 4ltwA-5ugjA:
undetectable		 4ltwA-5ugjA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 PHE A 221
ILE A 136
ALA A 176
ILE A 150
VAL A 174
 None
 1.10A 4nkxD-5ugjA:
undetectable		 4nkxD-5ugjA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 GLY A 215
THR A 207
GLU A 154
ARG A 237
 None
 1.09A 5btaA-5ugjA:
undetectable
5btaB-5ugjA:
undetectable
5btaC-5ugjA:
undetectable		 5btaA-5ugjA:
11.67
5btaB-5ugjA:
14.84
5btaC-5ugjA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 ARG A 237
GLY A 215
THR A 207
GLU A 154
 None
 1.07A 5btcA-5ugjA:
undetectable
5btcC-5ugjA:
undetectable
5btcD-5ugjA:
undetectable		 5btcA-5ugjA:
11.67
5btcC-5ugjA:
11.67
5btcD-5ugjA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 GLY A 215
THR A 207
GLU A 154
ARG A 237
 None
 1.11A 5btcA-5ugjA:
undetectable
5btcB-5ugjA:
2.4
5btcC-5ugjA:
undetectable		 5btcA-5ugjA:
11.67
5btcB-5ugjA:
14.84
5btcC-5ugjA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		5 / 11 ALA A  11
GLU A  36
LEU A  45
GLY A  56
LEU A  31
 None
 1.24A 5dxgB-5ugjA:
undetectable		 5dxgB-5ugjA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 GLU A 151
GLY A 204
ARG A 191
ARG A 181
 None
 1.26A 5jcnB-5ugjA:
4.0		 5jcnB-5ugjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5ugj 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE
(Neisseria
meningitidis) 		4 / 4 GLY A  48
LEU A  53
VAL A  51
GLU A  21
 None
 1.16A 5yw0A-5ugjA:
undetectable		 5yw0A-5ugjA:
undetectable