SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BZF_A_TMQA170_1 (DIHYDROFOLATE REDUCTASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	LEU D 560 ALA D 555 PHE D 512 PHE D 532 LEU D 524	None	1.10A	1bzfA-5uheD: undetectable	1bzfA-5uheD: 9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	0.87A	1nodB-5uheD: undetectable	1nodB-5uheD: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QOM_A_H4BA902_1 (NITRIC OXIDE SYNTHASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	0.98A	1qomA-5uheD: undetectable	1qomA-5uheD: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_A_NCTA1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TYR D 587 THR D 667 TRP D 723 MET D 672	None	1.34A	1uw6A-5uheD: undetectable 1uw6B-5uheD: undetectable	1uw6A-5uheD: 9.04 1uw6B-5uheD: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_D_NCTD1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TYR D 587 THR D 667 TRP D 723 MET D 672	None	1.33A	1uw6D-5uheD: undetectable 1uw6E-5uheD: undetectable	1uw6D-5uheD: 9.04 1uw6E-5uheD: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_G_NCTG1206_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TYR D 587 THR D 667 TRP D 723 MET D 672	None	1.29A	1uw6G-5uheD: undetectable 1uw6H-5uheD: undetectable	1uw6G-5uheD: 9.04 1uw6H-5uheD: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_P_NCTP1206_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TYR D 587 THR D 667 TRP D 723 MET D 672	None	1.32A	1uw6P-5uheD: undetectable 1uw6Q-5uheD: undetectable	1uw6P-5uheD: 9.04 1uw6Q-5uheD: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_T_NCTT1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TRP D 723 MET D 672 TYR D 587 THR D 667	None	1.32A	1uw6P-5uheD: undetectable 1uw6T-5uheD: undetectable	1uw6P-5uheD: 9.04 1uw6T-5uheD: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	0.95A	1v54A-5uheD: 4.0 1v54J-5uheD: undetectable	1v54A-5uheD: 17.15 1v54J-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D55_C_DVAC8_0 (ACTINOMYCIN D)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	PRO D 398 THR D 392 PRO D 394	None	0.81A	2d55C-5uheD: undetectable	2d55C-5uheD: 0.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	0.99A	2dyrA-5uheD: undetectable 2dyrJ-5uheD: undetectable	2dyrA-5uheD: 17.15 2dyrJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_J_CHDJ101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	0.99A	2dysA-5uheD: undetectable 2dysJ-5uheD: 1.2	2dysA-5uheD: 17.15 2dysJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	0.97A	2eijA-5uheD: 4.9 2eijJ-5uheD: undetectable	2eijA-5uheD: 17.15 2eijJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	0.96A	2eilA-5uheD: 4.1 2eilJ-5uheD: undetectable	2eilA-5uheD: 17.15 2eilJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_B_SC2B1290_1 (FICOLIN-2)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	LEU D 405 SER D 401 LEU D 340 ASP D 383	None	0.82A	2j2pA-5uheD: undetectable 2j2pB-5uheD: undetectable	2j2pA-5uheD: 9.87 2j2pB-5uheD: 9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	0.86A	2nodB-5uheD: undetectable	2nodB-5uheD: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_D_ASDD1224_1 (GLUTATHIONE S-TRANSFERASE A3)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 9	PRO D 546 LEU D 545 ALA D 551 LEU D 547 PHE D 455	None	1.11A	2vcvD-5uheD: undetectable	2vcvD-5uheD: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_I_ASDI1224_1 (GLUTATHIONE S-TRANSFERASE A3)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 9	PRO D 546 LEU D 545 ALA D 551 LEU D 547 PHE D 455	None	1.17A	2vcvI-5uheD: 2.2	2vcvI-5uheD: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1161_1 (ALLERGEN ARG R 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 5	VAL D 965 TYR D 979 VAL D 995 SER D 881	None	1.28A	2x45A-5uheD: undetectable	2x45A-5uheD: 6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_B_HSMB1161_1 (ALLERGEN ARG R 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 4	VAL D 965 TYR D 979 VAL D 995 SER D 881	None	1.27A	2x45B-5uheD: undetectable	2x45B-5uheD: 6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1161_1 (ALLERGEN ARG R 1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 5	VAL D 965 TYR D 979 VAL D 995 SER D 881	None	1.27A	2x45C-5uheD: undetectable	2x45C-5uheD: 6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	1.03A	3asnA-5uheD: 4.9 3asnJ-5uheD: 1.2	3asnA-5uheD: 17.15 3asnJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	LEU D1034 ARG D1159 MET D1161 LEU D1207	None	1.03A	3asoA-5uheD: 3.7 3asoJ-5uheD: 1.2	3asoA-5uheD: 17.15 3asoJ-5uheD: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7I_B_H4BB2902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	0.93A	3e7iB-5uheD: undetectable	3e7iB-5uheD: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_B_LYAB514_2 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 556 THR D 985 THR D1262	None	0.79A	3k2hB-5uheD: undetectable	3k2hB-5uheD: 17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MEC_A_65BA561_0 (P66 REVERSE TRANSCRIPTASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	LEU D 118 VAL D 135 PHE D 107 LEU D 114 PRO D 122	None	1.13A	3mecA-5uheD: undetectable	3mecA-5uheD: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_A_AICA375_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 11	ASN D 341 SER D 338 LEU D 324 LEU D 402 LEU D 405	None	1.38A	3ndvA-5uheD: undetectable 3ndvB-5uheD: undetectable	3ndvA-5uheD: 15.47 3ndvB-5uheD: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_B_AICB376_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 11	LEU D 402 LEU D 405 ASN D 341 SER D 338 LEU D 324	None	1.37A	3ndvA-5uheD: undetectable 3ndvB-5uheD: undetectable	3ndvA-5uheD: 15.47 3ndvB-5uheD: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_C_AICC375_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 11	ASN D 341 SER D 338 LEU D 324 LEU D 402 LEU D 405	None	1.36A	3ndvC-5uheD: undetectable 3ndvD-5uheD: undetectable	3ndvC-5uheD: 15.47 3ndvD-5uheD: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_D_AICD374_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 11	LEU D 402 LEU D 405 ASN D 341 SER D 338 LEU D 324	None	1.37A	3ndvC-5uheD: undetectable 3ndvD-5uheD: undetectable	3ndvC-5uheD: 15.47 3ndvD-5uheD: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	1.03A	3nw2A-5uheD: undetectable	3nw2A-5uheD: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_B_H4BB902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 113 ILE D 104 TRP D 105	None	0.92A	3nw2B-5uheD: undetectable	3nw2B-5uheD: 15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_A_RITA600_1 (CYTOCHROME P450 3A4)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	ALA D 954 ILE D 957 ALA D 929 GLU D 939 GLY D 934	None	1.03A	3nxuA-5uheD: undetectable	3nxuA-5uheD: 16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_A_BEZA264_0 (ECHA1_1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	ALA D1236 ILE D 12 ALA D1224 ALA D1223	None	0.69A	3r9tA-5uheD: undetectable	3r9tA-5uheD: 13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_A_DXCA91_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	PHE D 532 GLN D1001 PHE D 512	None	0.64A	3rv5A-5uheD: 1.0	3rv5A-5uheD: 5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	TYR D1142 VAL D1031 LEU D1134 ALA D 999 ILE D1210	None	1.08A	3w67C-5uheD: undetectable	3w67C-5uheD: 11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_D_ACHD301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	TYR D 587 THR D 667 TRP D 723 MET D 672	None	1.27A	3wipD-5uheD: undetectable 3wipE-5uheD: undetectable	3wipD-5uheD: 9.95 3wipE-5uheD: 9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F93_B_SANB3004_1 (U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	GLU D 993 HIS D1153 GLY D 571 SER D 570	None	0.91A	4f93B-5uheD: undetectable	4f93B-5uheD: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J26_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	LEU D1221 LEU D 417 LEU D 418 GLY D 411 LEU D 406	None	1.28A	4j26A-5uheD: undetectable	4j26A-5uheD: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KIC_B_SAMB401_1 (METHYLTRANSFERASE MPPJ)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 345 ASP D 339 ASP D 404	None	0.90A	4kicB-5uheD: undetectable	4kicB-5uheD: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_C_TMQC202_1 (DIHYDROFOLATE REDUCTASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	ILE D 957 ALA D 902 ILE D 916 LEU D 944 LEU D 925	None	1.04A	4m2xC-5uheD: undetectable	4m2xC-5uheD: 8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PSS_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	6 / 12	ILE D1157 LEU D1034 ALA D1037 PHE D1035 LEU D 873 ILE D1003	None	1.50A	4pssA-5uheD: undetectable	4pssA-5uheD: 8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_D_PARD500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	THR D 801 SER D 805 ASP D 795 ASP D 796	None	1.36A	4qb9D-5uheD: undetectable	4qb9D-5uheD: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R87_J_SPMJ202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 7	MET D 143 GLU D 147 TYR D 248 GLU D 250	None	1.42A	4r87J-5uheD: undetectable 4r87L-5uheD: undetectable	4r87J-5uheD: 9.58 4r87L-5uheD: 9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RDX_A_HISA502_0 (HISTIDINE--TRNA LIGASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 7	THR D1229 ARG D 412 GLY D 411 GLY D 408	None	0.83A	4rdxA-5uheD: undetectable	4rdxA-5uheD: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YHA_A_MZMA303_1 (ALPHA-CARBONIC ANHYDRASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	ASP D 379 VAL D 378 VAL D 347 LEU D 97 ALA D 99	None	1.32A	4yhaA-5uheD: undetectable	4yhaA-5uheD: 9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZ8_A_GCSA208_1 (GLUCANASE/CHITOSANAS E)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 7	ARG D1123 TYR D1077 GLU D1120 ASP D1117	None	1.20A	4zz8A-5uheD: undetectable	4zz8A-5uheD: 6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_1 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 670 LYS D 632 GLU D 591	None	0.75A	5d0yA-5uheD: 2.6	5d0yA-5uheD: 8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_Y_BEZY801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 5	ILE D 832 GLY D 822 ILE D 851 LEU D 823	None None 88G D1404 (-3.5A) None	0.89A	5dzkd-5uheD: undetectable 5dzkk-5uheD: undetectable 5dzky-5uheD: undetectable	5dzkd-5uheD: 10.36 5dzkk-5uheD: 9.99 5dzky-5uheD: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWZ_D_010D6_0 (N-[(5-METHYLISOXAZOL -3-YL)CARBONYL]ALANY L-L-VALYL-N~1~-((1R, 2Z)-4-(BENZYLOXY)-4- OXO-1-{[(3R)-2-OXOPY RROLIDIN-3-YL]METHYL }BUT-2-ENYL)-L-LEUCI NAMIDE PEDV MAIN PROTEASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	MET D 983 HIS D1150 GLY D 980	None	0.87A	5gwzB-5uheD: undetectable	5gwzB-5uheD: 13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_B_SAMB301_1 (CAFFEOYL-COA O-METHYLTRANSFERASE)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	THR D1230 SER D 403 ASP D 379	None	0.83A	5kvaB-5uheD: undetectable	5kvaB-5uheD: 11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MRA_B_DM2B204_1 (SORCIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	THR D1065 ARG D1054 ASP D1101 GLY D1102	None	1.25A	5mraA-5uheD: undetectable 5mraB-5uheD: undetectable	5mraA-5uheD: 8.89 5mraB-5uheD: 8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UOC_B_H4BB502_1 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	TRP D 662 PHE D 683 VAL D 635 ARG D 670	None	1.50A	5uocA-5uheD: 0.0 5uocB-5uheD: 0.1	5uocA-5uheD: 15.28 5uocB-5uheD: 15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2T_B_8LXB501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 12	CYH D 441 GLN D 440 ILE D 491 ILE D 522 MET D 541	None	1.17A	5y2tB-5uheD: undetectable	5y2tB-5uheD: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YVN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 6	GLU D 675 GLN D 639 LEU D 637 LEU D 640	None	1.04A	5yvnA-5uheD: 2.5	5yvnA-5uheD: 10.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BZO_C_FI8C1201_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	5 / 9	ARG D 84 GLU D 323 LEU D 324 PRO D 326 SER D 338	None	1.01A	6bzoD-5uheD: 32.8	6bzoD-5uheD: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6FBV_D_FI8D1904_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	ASP D 57 ARG D 84 GLU D 323 VAL D 328	None	1.09A	6fbvD-5uheD: undetectable	6fbvD-5uheD: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA819_0 (GEPHYRIN)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	3 / 3	ARG D 173 GLY D 201 GLU D 202	None	0.55A	6fgdA-5uheD: undetectable	6fgdA-5uheD: 15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GIQ_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5uhe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' (Mycobacterium tuberculosis)	4 / 8	ASP D 795 GLY D 819 SER D 839 VAL D 736	None	0.81A	6giqL-5uheD: undetectable 6giqP-5uheD: undetectable 6giqT-5uheD: undetectable	6giqL-5uheD: 15.27 6giqP-5uheD: 10.76 6giqT-5uheD: 3.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BZF_A_TMQA170_1","DIHYDROFOLATE REDUCTASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"LEU D 560;ALA D 555;PHE D 512;PHE D 532;LEU D 524","None","1.10A","1bzfA-5uheD:undetectable","1bzfA-5uheD:9.18"],["1NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","0.87A","1nodB-5uheD:undetectable","1nodB-5uheD:15.80"],["1QOM_A_H4BA902_1","NITRIC OXIDE SYNTHASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","0.98A","1qomA-5uheD:undetectable","1qomA-5uheD:15.57"],["1UW6_A_NCTA1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TYR D 587;THR D 667;TRP D 723;MET D 672","None","1.34A","1uw6A-5uheD:undetectable;1uw6B-5uheD:undetectable","1uw6A-5uheD:9.04;1uw6B-5uheD:9.04"],["1UW6_D_NCTD1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TYR D 587;THR D 667;TRP D 723;MET D 672","None","1.33A","1uw6D-5uheD:undetectable;1uw6E-5uheD:undetectable","1uw6D-5uheD:9.04;1uw6E-5uheD:9.04"],["1UW6_G_NCTG1206_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TYR D 587;THR D 667;TRP D 723;MET D 672","None","1.29A","1uw6G-5uheD:undetectable;1uw6H-5uheD:undetectable","1uw6G-5uheD:9.04;1uw6H-5uheD:9.04"],["1UW6_P_NCTP1206_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TYR D 587;THR D 667;TRP D 723;MET D 672","None","1.32A","1uw6P-5uheD:undetectable;1uw6Q-5uheD:undetectable","1uw6P-5uheD:9.04;1uw6Q-5uheD:9.04"],["1UW6_T_NCTT1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TRP D 723;MET D 672;TYR D 587;THR D 667","None","1.32A","1uw6P-5uheD:undetectable;1uw6T-5uheD:undetectable","1uw6P-5uheD:9.04;1uw6T-5uheD:9.04"],["1V54_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","0.95A","1v54A-5uheD:4.0;1v54J-5uheD:undetectable","1v54A-5uheD:17.15;1v54J-5uheD:6.64"],["2D55_C_DVAC8_0","ACTINOMYCIN D","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"PRO D 398;THR D 392;PRO D 394","None","0.81A","2d55C-5uheD:undetectable","2d55C-5uheD:0.88"],["2DYR_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","0.99A","2dyrA-5uheD:undetectable;2dyrJ-5uheD:undetectable","2dyrA-5uheD:17.15;2dyrJ-5uheD:6.64"],["2DYS_J_CHDJ101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","0.99A","2dysA-5uheD:undetectable;2dysJ-5uheD:1.2","2dysA-5uheD:17.15;2dysJ-5uheD:6.64"],["2EIJ_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","0.97A","2eijA-5uheD:4.9;2eijJ-5uheD:undetectable","2eijA-5uheD:17.15;2eijJ-5uheD:6.64"],["2EIL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","0.96A","2eilA-5uheD:4.1;2eilJ-5uheD:undetectable","2eilA-5uheD:17.15;2eilJ-5uheD:6.64"],["2J2P_B_SC2B1290_1","FICOLIN-2;FICOLIN-2","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D 405;SER D 401;LEU D 340;ASP D 383","None","0.82A","2j2pA-5uheD:undetectable;2j2pB-5uheD:undetectable","2j2pA-5uheD:9.87;2j2pB-5uheD:9.87"],["2NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","0.86A","2nodB-5uheD:undetectable","2nodB-5uheD:15.80"],["2VCV_D_ASDD1224_1","GLUTATHIONE S-TRANSFERASE A3","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"PRO D 546;LEU D 545;ALA D 551;LEU D 547;PHE D 455","None","1.11A","2vcvD-5uheD:undetectable","2vcvD-5uheD:10.79"],["2VCV_I_ASDI1224_1","GLUTATHIONE S-TRANSFERASE A3","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"PRO D 546;LEU D 545;ALA D 551;LEU D 547;PHE D 455","None","1.17A","2vcvI-5uheD:2.2","2vcvI-5uheD:10.79"],["2X45_A_HSMA1161_1","ALLERGEN ARG R 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"VAL D 965;TYR D 979;VAL D 995;SER D 881","None","1.28A","2x45A-5uheD:undetectable","2x45A-5uheD:6.97"],["2X45_B_HSMB1161_1","ALLERGEN ARG R 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"VAL D 965;TYR D 979;VAL D 995;SER D 881","None","1.27A","2x45B-5uheD:undetectable","2x45B-5uheD:6.97"],["2X45_C_HSMC1161_1","ALLERGEN ARG R 1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"VAL D 965;TYR D 979;VAL D 995;SER D 881","None","1.27A","2x45C-5uheD:undetectable","2x45C-5uheD:6.97"],["3ASN_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","1.03A","3asnA-5uheD:4.9;3asnJ-5uheD:1.2","3asnA-5uheD:17.15;3asnJ-5uheD:6.64"],["3ASO_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"LEU D1034;ARG D1159;MET D1161;LEU D1207","None","1.03A","3asoA-5uheD:3.7;3asoJ-5uheD:1.2","3asoA-5uheD:17.15;3asoJ-5uheD:6.64"],["3E7I_B_H4BB2902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","0.93A","3e7iB-5uheD:undetectable","3e7iB-5uheD:15.90"],["3K2H_B_LYAB514_2","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 556;THR D 985;THR D1262","None","0.79A","3k2hB-5uheD:undetectable","3k2hB-5uheD:17.11"],["3MEC_A_65BA561_0","P66 REVERSE TRANSCRIPTASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"LEU D 118;VAL D 135;PHE D 107;LEU D 114;PRO D 122","None","1.13A","3mecA-5uheD:undetectable","3mecA-5uheD:18.33"],["3NDV_A_AICA375_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ASN D 341;SER D 338;LEU D 324;LEU D 402;LEU D 405","None","1.38A","3ndvA-5uheD:undetectable;3ndvB-5uheD:undetectable","3ndvA-5uheD:15.47;3ndvB-5uheD:15.47"],["3NDV_B_AICB376_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"LEU D 402;LEU D 405;ASN D 341;SER D 338;LEU D 324","None","1.37A","3ndvA-5uheD:undetectable;3ndvB-5uheD:undetectable","3ndvA-5uheD:15.47;3ndvB-5uheD:15.47"],["3NDV_C_AICC375_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ASN D 341;SER D 338;LEU D 324;LEU D 402;LEU D 405","None","1.36A","3ndvC-5uheD:undetectable;3ndvD-5uheD:undetectable","3ndvC-5uheD:15.47;3ndvD-5uheD:15.47"],["3NDV_D_AICD374_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"LEU D 402;LEU D 405;ASN D 341;SER D 338;LEU D 324","None","1.37A","3ndvC-5uheD:undetectable;3ndvD-5uheD:undetectable","3ndvC-5uheD:15.47;3ndvD-5uheD:15.47"],["3NW2_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","1.03A","3nw2A-5uheD:undetectable","3nw2A-5uheD:15.80"],["3NW2_B_H4BB902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 113;ILE D 104;TRP D 105","None","0.92A","3nw2B-5uheD:undetectable","3nw2B-5uheD:15.80"],["3NXU_A_RITA600_1","CYTOCHROME P450 3A4","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ALA D 954;ILE D 957;ALA D 929;GLU D 939;GLY D 934","None","1.03A","3nxuA-5uheD:undetectable","3nxuA-5uheD:16.70"],["3R9T_A_BEZA264_0","ECHA1_1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"ALA D1236;ILE D  12;ALA D1224;ALA D1223","None","0.69A","3r9tA-5uheD:undetectable","3r9tA-5uheD:13.12"],["3RV5_A_DXCA91_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"PHE D 532;GLN D1001;PHE D 512","None","0.64A","3rv5A-5uheD:1.0","3rv5A-5uheD:5.18"],["3W67_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"TYR D1142;VAL D1031;LEU D1134;ALA D 999;ILE D1210","None","1.08A","3w67C-5uheD:undetectable","3w67C-5uheD:11.87"],["3WIP_D_ACHD301_0","ACETYLCHOLINE-BINDING PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TYR D 587;THR D 667;TRP D 723;MET D 672","None","1.27A","3wipD-5uheD:undetectable;3wipE-5uheD:undetectable","3wipD-5uheD:9.95;3wipE-5uheD:9.95"],["4F93_B_SANB3004_1","U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"GLU D 993;HIS D1153;GLY D 571;SER D 570","None","0.91A","4f93B-5uheD:undetectable","4f93B-5uheD:22.65"],["4J26_A_ESTA600_1","ESTROGEN RECEPTOR BETA","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"LEU D1221;LEU D 417;LEU D 418;GLY D 411;LEU D 406","None","1.28A","4j26A-5uheD:undetectable","4j26A-5uheD:10.80"],["4KIC_B_SAMB401_1","METHYLTRANSFERASE MPPJ","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 345;ASP D 339;ASP D 404","None","0.90A","4kicB-5uheD:undetectable","4kicB-5uheD:15.30"],["4M2X_C_TMQC202_1","DIHYDROFOLATE REDUCTASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ILE D 957;ALA D 902;ILE D 916;LEU D 944;LEU D 925","None","1.04A","4m2xC-5uheD:undetectable","4m2xC-5uheD:8.23"],["4PSS_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",6,"ILE D1157;LEU D1034;ALA D1037;PHE D1035;LEU D 873;ILE D1003","None","1.50A","4pssA-5uheD:undetectable","4pssA-5uheD:8.05"],["4QB9_D_PARD500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"THR D 801;SER D 805;ASP D 795;ASP D 796","None","1.36A","4qb9D-5uheD:undetectable","4qb9D-5uheD:16.06"],["4R87_J_SPMJ202_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"MET D 143;GLU D 147;TYR D 248;GLU D 250","None","1.42A","4r87J-5uheD:undetectable;4r87L-5uheD:undetectable","4r87J-5uheD:9.58;4r87L-5uheD:9.58"],["4RDX_A_HISA502_0","HISTIDINE--TRNA LIGASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"THR D1229;ARG D 412;GLY D 411;GLY D 408","None","0.83A","4rdxA-5uheD:undetectable","4rdxA-5uheD:17.18"],["4YHA_A_MZMA303_1","ALPHA-CARBONIC ANHYDRASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ASP D 379;VAL D 378;VAL D 347;LEU D  97;ALA D  99","None","1.32A","4yhaA-5uheD:undetectable","4yhaA-5uheD:9.73"],["4ZZ8_A_GCSA208_1","GLUCANASE\/CHITOSANASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"ARG D1123;TYR D1077;GLU D1120;ASP D1117","None","1.20A","4zz8A-5uheD:undetectable","4zz8A-5uheD:6.86"],["5D0Y_A_FOLA201_1","CONSERVED HYPOTHETICAL MEMBRANE PROTEIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 670;LYS D 632;GLU D 591","None","0.75A","5d0yA-5uheD:2.6","5d0yA-5uheD:8.30"],["5DZK_Y_BEZY801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"ILE D 832;GLY D 822;ILE D 851;LEU D 823","None;None;88G D1404 (-3.5A);None","0.89A","5dzkd-5uheD:undetectable;5dzkk-5uheD:undetectable;5dzky-5uheD:undetectable","5dzkd-5uheD:10.36;5dzkk-5uheD:9.99;5dzky-5uheD:20.00"],["5GWZ_D_010D6_0","N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE;PEDV MAIN PROTEASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"MET D 983;HIS D1150;GLY D 980","None","0.87A","5gwzB-5uheD:undetectable","5gwzB-5uheD:13.28"],["5KVA_B_SAMB301_1","CAFFEOYL-COA O-METHYLTRANSFERASE","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"THR D1230;SER D 403;ASP D 379","None","0.83A","5kvaB-5uheD:undetectable","5kvaB-5uheD:11.18"],["5MRA_B_DM2B204_1","SORCIN;SORCIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"THR D1065;ARG D1054;ASP D1101;GLY D1102","None","1.25A","5mraA-5uheD:undetectable;5mraB-5uheD:undetectable","5mraA-5uheD:8.89;5mraB-5uheD:8.89"],["5UOC_B_H4BB502_1","NITRIC OXIDE SYNTHASE, ENDOTHELIAL;NITRIC OXIDE SYNTHASE, ENDOTHELIAL","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"TRP D 662;PHE D 683;VAL D 635;ARG D 670","None","1.50A","5uocA-5uheD:0.0;5uocB-5uheD:0.1","5uocA-5uheD:15.28;5uocB-5uheD:15.28"],["5Y2T_B_8LXB501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"CYH D 441;GLN D 440;ILE D 491;ILE D 522;MET D 541","None","1.17A","5y2tB-5uheD:undetectable","5y2tB-5uheD:undetectable"],["5YVN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE OMEGA-1","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"GLU D 675;GLN D 639;LEU D 637;LEU D 640","None","1.04A","5yvnA-5uheD:2.5","5yvnA-5uheD:10.27"],["6BZO_C_FI8C1201_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",5,"ARG D  84;GLU D 323;LEU D 324;PRO D 326;SER D 338","None","1.01A","6bzoD-5uheD:32.8","6bzoD-5uheD:100.00"],["6FBV_D_FI8D1904_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"ASP D  57;ARG D  84;GLU D 323;VAL D 328","None","1.09A","6fbvD-5uheD:undetectable","6fbvD-5uheD:100.00"],["6FGD_A_ACTA819_0","GEPHYRIN","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",3,"ARG D 173;GLY D 201;GLU D 202","None","0.55A","6fgdA-5uheD:undetectable","6fgdA-5uheD:15.01"],["6GIQ_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5uhe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","Mycobacterium tuberculosis",4,"ASP D 795;GLY D 819;SER D 839;VAL D 736","None","0.81A","6giqL-5uheD:undetectable;6giqP-5uheD:undetectable;6giqT-5uheD:undetectable","6giqL-5uheD:15.27;6giqP-5uheD:10.76;6giqT-5uheD:3.88"]]