SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uhj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M9Q_B_BEZB251_0 (SERINE PROTEASE INHIBITOR SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3)	5uhj	GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE (Streptomyces sp. CB03234)	5 / 9	ILE A 53 ILE A 8 PHE A 119 THR A 72 LEU A 76	None	1.18A	2m9qA-5uhjA: undetectable	2m9qA-5uhjA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5uhj	GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE (Streptomyces sp. CB03234)	4 / 6	LEU A 121 PHE A 119 PHE A 111 LEU A 88	None	0.84A	3abkP-5uhjA: undetectable 3abkW-5uhjA: undetectable	3abkP-5uhjA: 19.14 3abkW-5uhjA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	5uhj	GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE (Streptomyces sp. CB03234)	4 / 5	LEU A 121 PHE A 119 PHE A 111 LEU A 88	None	0.83A	5x1bP-5uhjA: undetectable	5x1bP-5uhjA: 19.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2M9Q_B_BEZB251_0","SERINE PROTEASE INHIBITOR;SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3","5uhj","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","Streptomyces sp. CB03234",5,"ILE A  53;ILE A   8;PHE A 119;THR A  72;LEU A  76","None","1.18A","2m9qA-5uhjA:undetectable","2m9qA-5uhjA:16.67"],["3ABK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5uhj","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","Streptomyces sp. CB03234",4,"LEU A 121;PHE A 119;PHE A 111;LEU A  88","None","0.84A","3abkP-5uhjA:undetectable;3abkW-5uhjA:undetectable","3abkP-5uhjA:19.14;3abkW-5uhjA:20.83"],["5X1B_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","5uhj","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","Streptomyces sp. CB03234",4,"LEU A 121;PHE A 119;PHE A 111;LEU A  88","None","0.83A","5x1bP-5uhjA:undetectable","5x1bP-5uhjA:19.14"]]