SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		5 / 12 GLY H  65
SER H 112
TYR H  90
LEU H  69
MET H  80
 None
 1.43A 1fm6D-5uhyH:
undetectable		 1fm6D-5uhyH:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.59A 4x1iA-5uhyH:
undetectable		 4x1iA-5uhyH:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		5 / 12 SER H 215
LEU H 178
ALA H  84
LEU H  82
THR H   9
 None
 1.25A 4x1kA-5uhyH:
undetectable
4x1kB-5uhyH:
undetectable		 4x1kA-5uhyH:
17.96
4x1kB-5uhyH:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.55A 5eypA-5uhyH:
undetectable		 5eypA-5uhyH:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		4 / 5 SER H  75
SER H  76
SER H  77
SER H  25
 None
 1.31A 5hswA-5uhyH:
undetectable		 5hswA-5uhyH:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5uhy ZV67 FAB CHAIN 2
(Homo
sapiens) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.52A 5xiwC-5uhyH:
undetectable		 5xiwC-5uhyH:
18.06