SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ui2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 ILE A 305
ALA A 304
LEU A 225
ALA A 224
VAL A 275
 EQ3  A 403 ( 3.8A)
None
None
None
EQ3  A 403 (-4.7A)
 1.00A 1fm6A-5ui2A:
undetectable		 1fm6A-5ui2A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 5 TYR A 266
PRO A 261
THR A   4
THR A   7
 None
 1.40A 1ymxB-5ui2A:
undetectable		 1ymxB-5ui2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 PRO A 228
PRO A 103
ILE A 288
VAL A 275
LEU A 252
 None
None
None
EQ3  A 403 (-4.7A)
EQ3  A 403 (-4.4A)
 1.18A 1z9hD-5ui2A:
undetectable		 1z9hD-5ui2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_1
(HYPOTHETICAL PROTEIN
LMO1582)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 4 THR A  75
THR A  80
ASP A  85
ASP A  91
 None
 1.41A 2f8lA-5ui2A:
undetectable		 2f8lA-5ui2A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 5 ILE A 288
PHE A 292
PRO A 228
PHE A 243
 None
 1.28A 2ygnA-5ui2A:
undetectable		 2ygnA-5ui2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 10 GLU A 255
ILE A 192
GLY A 257
LEU A 294
MET A 204
 None
 1.48A 3adsA-5ui2A:
undetectable		 3adsA-5ui2A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 ILE A  40
TRP A  41
ALA A  38
LEU A 131
LEU A  31
 EQ3  A 403 (-3.9A)
None
None
None
None
 0.96A 3ix9A-5ui2A:
undetectable		 3ix9A-5ui2A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 ILE A 151
GLY A 148
ALA A  18
PHE A 280
ILE A 145
 EQ3  A 403 (-3.9A)
None
None
EQ3  A 403 ( 4.7A)
None
 0.90A 3jayA-5ui2A:
undetectable		 3jayA-5ui2A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 ILE A 151
GLY A 148
ALA A  18
PHE A 280
ILE A 145
 EQ3  A 403 (-3.9A)
None
None
EQ3  A 403 ( 4.7A)
None
 1.00A 3jb1A-5ui2A:
undetectable		 3jb1A-5ui2A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 7 PHE A  12
THR A  15
ASP A 306
ILE A  11
 None
 1.11A 3t01A-5ui2A:
undetectable		 3t01A-5ui2A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 8 PRO A 228
PHE A 242
TRP A 290
TYR A 203
 None
None
EQ3  A 403 (-4.2A)
EQ3  A 403 (-4.6A)
 1.30A 4v2zC-5ui2A:
undetectable		 4v2zC-5ui2A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 6 LYS A 167
TYR A 171
ALA A  99
ARG A  96
 None
 1.29A 4yshB-5ui2A:
undetectable		 4yshB-5ui2A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 8 PHE A 301
ALA A 220
LEU A 294
LEU A 293
 None
 1.02A 5dzkF-5ui2A:
undetectable
5dzkT-5ui2A:
undetectable		 5dzkF-5ui2A:
21.34
5dzkT-5ui2A:
0.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		3 / 3 ASP A 211
ASN A 249
GLN A 248
 None
SUC  A 401 (-3.6A)
None
 0.80A 5k7uA-5ui2A:
undetectable		 5k7uA-5ui2A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 8 ARG A 115
GLU A 112
GLY A  57
PRO A  56
 None
None
SUC  A 401 (-4.2A)
SUC  A 401 (-3.8A)
 0.88A 5kf8A-5ui2A:
undetectable		 5kf8A-5ui2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 8 ARG A 115
GLU A 112
GLY A  57
PRO A  56
 None
None
SUC  A 401 (-4.2A)
SUC  A 401 (-3.8A)
 0.94A 5kgpA-5ui2A:
undetectable		 5kgpA-5ui2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		4 / 8 ARG A 115
GLU A 112
GLY A  57
PRO A  56
 None
None
SUC  A 401 (-4.2A)
SUC  A 401 (-3.8A)
 0.94A 5kgpB-5ui2A:
undetectable		 5kgpB-5ui2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 12 ILE A 305
ALA A 304
LEU A 225
ALA A 224
VAL A 275
 EQ3  A 403 ( 3.8A)
None
None
None
EQ3  A 403 (-4.7A)
 0.95A 5uanA-5ui2A:
undetectable		 5uanA-5ui2A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN
(Arthrospira
maxima) 		5 / 10 ILE A  25
ILE A 125
ALA A  38
LEU A  39
ALA A 135
 None
 1.20A 5zjiB-5ui2A:
undetectable		 5zjiB-5ui2A:
13.68