SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ui3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		4 / 8 LYS D  33
THR D  34
GLY D  66
LEU D  82
 None
None
AKG  D 401 ( 3.8A)
None
 0.82A 1aegA-5ui3D:
undetectable		 1aegA-5ui3D:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 THR D 112
GLY D 149
GLU D 113
SER D 123
HIS D 141
 None
 1.42A 1jdvE-5ui3D:
undetectable
1jdvF-5ui3D:
undetectable		 1jdvE-5ui3D:
18.31
1jdvF-5ui3D:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 10 GLY D 115
VAL D 118
GLY D 119
THR D 112
VAL D  80
 None
 1.12A 1pwyE-5ui3D:
undetectable		 1pwyE-5ui3D:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 10 GLY D 115
VAL D 118
GLY D 119
THR D 112
VAL D  80
 None
 1.21A 1v3qE-5ui3D:
undetectable		 1v3qE-5ui3D:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 TRP D 201
ALA D 211
VAL D 218
 None
 0.99A 1w5uA-5ui3D:
undetectable
1w5uB-5ui3D:
undetectable		 1w5uA-5ui3D:
undetectable
1w5uB-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 SER D 222
VAL D  59
LEU D  28
 None
 0.74A 1yajG-5ui3D:
undetectable		 1yajG-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		4 / 8 THR D  86
VAL D  87
VAL D 118
ALA D 122
 None
 1.04A 2ij7C-5ui3D:
undetectable		 2ij7C-5ui3D:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 ALA D 211
VAL D 218
TRP D 201
 None
 0.91A 2izqA-5ui3D:
undetectable
2izqB-5ui3D:
undetectable		 2izqA-5ui3D:
undetectable
2izqB-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		4 / 5 VAL D  87
THR D  86
VAL D  64
GLY D  98
 None
 1.12A 2p2fA-5ui3D:
undetectable		 2p2fA-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		4 / 4 VAL D  87
THR D  86
VAL D  64
GLY D  98
 None
 1.13A 2p2fB-5ui3D:
undetectable		 2p2fB-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU D 124
ILE D 190
SER D 123
VAL D 145
VAL D 169
 None
 1.32A 2pnjB-5ui3D:
undetectable		 2pnjB-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU D 268
PRO D 261
THR D  68
GLY D  69
GLY D  65
 None
None
AKG  D 401 (-3.6A)
None
None
 1.13A 2uvnA-5ui3D:
undetectable		 2uvnA-5ui3D:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 ASP D 315
PHE D 318
LEU D 320
 None
 0.69A 2zi9A-5ui3D:
undetectable		 2zi9A-5ui3D:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		4 / 6 VAL D 283
GLN D 289
GLY D 293
LEU D 251
 None
 1.04A 3bjwE-5ui3D:
undetectable		 3bjwE-5ui3D:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 ASN D 245
MET D 236
GLY D 203
ILE D 190
ASN D 215
 None
 1.26A 3jb2A-5ui3D:
undetectable		 3jb2A-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 TRP D 201
ALA D 211
VAL D 218
 None
 0.99A 3l8lA-5ui3D:
undetectable
3l8lB-5ui3D:
undetectable		 3l8lA-5ui3D:
undetectable
3l8lB-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 PHE D 116
GLY D 149
ALA D 151
ILE D  63
ILE D  32
 None
None
None
AKG  D 401 ( 4.9A)
None
 1.06A 3ld6A-5ui3D:
undetectable		 3ld6A-5ui3D:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO D 240
SER D 214
ASN D 245
 None
 0.87A 3lslG-5ui3D:
undetectable		 3lslG-5ui3D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 ILE D 221
MET D 236
ARG D  27
 None
 0.77A 4lnwA-5ui3D:
undetectable		 4lnwA-5ui3D:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		3 / 3 ILE D 221
MET D 236
ARG D  27
 None
 0.78A 4lnxA-5ui3D:
undetectable		 4lnxA-5ui3D:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 5ui3 DIHYDRODIPICOLINATE
SYNTHASE
(Chlamydomonas
reinhardtii) 		5 / 12 PRO D 229
TYR D  47
THR D  68
ASN D 260
ILE D  32
 None
None
AKG  D 401 (-3.6A)
AKG  D 401 (-3.8A)
None
 1.32A 4xe0A-5ui3D:
undetectable		 4xe0A-5ui3D:
undetectable