SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ui5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 5ui5 RNA POLYMERASE SIGMA
FACTOR RPON
(Aquifex
aeolicus) 		5 / 12 LEU I 343
LEU I 346
ILE I 347
ILE I 350
LEU I 338
 None
 0.64A 1xdkB-5ui5I:
undetectable		 1xdkB-5ui5I:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5ui5 RNA POLYMERASE SIGMA
FACTOR RPON
(Aquifex
aeolicus) 		4 / 8 ILE I 162
LYS I 177
GLU I 179
ILE I 180
 None
 0.95A 2j9dJ-5ui5I:
undetectable
2j9dK-5ui5I:
undetectable
2j9dL-5ui5I:
undetectable		 2j9dJ-5ui5I:
16.37
2j9dK-5ui5I:
16.37
2j9dL-5ui5I:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5ui5 RNA POLYMERASE SIGMA
FACTOR RPON
(Aquifex
aeolicus) 		4 / 8 ILE I 347
VAL I 381
TYR I 360
ILE I 368
 None
 0.70A 5mzrE-5ui5I:
2.2		 5mzrE-5ui5I:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 5ui5 RNA POLYMERASE SIGMA
FACTOR RPON
(Aquifex
aeolicus) 		5 / 12 GLY I 287
GLN I 340
GLU I 342
LEU I 338
LEU I 343
 None
 1.28A 5nwwA-5ui5I:
undetectable		 5nwwA-5ui5I:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5ui5 RNA POLYMERASE SIGMA
FACTOR RPON
(Aquifex
aeolicus) 		4 / 8 GLU I 342
VAL I 331
GLY I 287
GLN I 279
 None
 1.06A 5syjA-5ui5I:
undetectable		 5syjA-5ui5I:
17.93