SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 11 ASN A 222
GLY A 223
ALA A 224
ILE A 248
GLY A 250
 None
 0.88A 1n49B-5uibA:
undetectable		 1n49B-5uibA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 11 ASN A 222
GLY A 223
ALA A 224
ILE A 248
GLY A 250
 None
 0.89A 1n49C-5uibA:
undetectable		 1n49C-5uibA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 187
LEU A 197
LEU A 218
ILE A 227
LEU A 325
 None
 1.21A 1xdkB-5uibA:
undetectable		 1xdkB-5uibA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 4 LEU A 191
PRO A 132
ILE A 255
LEU A 140
 None
 0.98A 1ya4B-5uibA:
2.2		 1ya4B-5uibA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.84A 2f81A-5uibA:
undetectable		 2f81A-5uibA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 ASP A 118
PRO A 120
MET A 122
THR A 312
GLY A 310
 None
 0.97A 2uvnA-5uibA:
undetectable		 2uvnA-5uibA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 7 PHE A 189
ILE A 190
THR A 314
ILE A 255
 None
 0.89A 2v0mB-5uibA:
undetectable		 2v0mB-5uibA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 1.02A 2z54A-5uibA:
undetectable		 2z54A-5uibA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 4 VAL A  46
ASP A  72
LEU A  83
ARG A  42
 None
 1.17A 2ziaA-5uibA:
2.0		 2ziaA-5uibA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 1.00A 3ndwA-5uibA:
undetectable		 3ndwA-5uibA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 10 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.94A 3nu6B-5uibA:
undetectable		 3nu6B-5uibA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.90A 3pwmB-5uibA:
undetectable		 3pwmB-5uibA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 ASN A 222
ASP A 219
VAL A 194
GLY A 151
ILE A 248
 None
 0.97A 3spkB-5uibA:
undetectable		 3spkB-5uibA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.88A 3tkgD-5uibA:
undetectable		 3tkgD-5uibA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 7 PRO A 242
LEU A 179
ASN A 126
ILE A 291
 None
TLA  A 402 (-4.0A)
NAD  A 401 (-3.0A)
NAD  A 401 ( 4.7A)
 0.98A 3u5jA-5uibA:
undetectable		 3u5jA-5uibA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 8 PRO A 242
LEU A 179
ASN A 126
ILE A 291
 None
TLA  A 402 (-4.0A)
NAD  A 401 (-3.0A)
NAD  A 401 ( 4.7A)
 0.82A 3u5kD-5uibA:
undetectable		 3u5kD-5uibA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 8 CYH A 114
LEU A 121
ILE A  95
PHE A 100
 None
 0.60A 3wzeA-5uibA:
undetectable		 3wzeA-5uibA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 7 MET A 122
ASP A 318
SER A 313
HIS A 301
 None
 1.33A 4aq7A-5uibA:
undetectable		 4aq7A-5uibA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		3 / 3 LYS A  44
LYS A  41
PRO A  40
 None
 1.05A 4dv1L-5uibA:
undetectable		 4dv1L-5uibA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLN A  97
ALA A  74
GLU A 125
HIS A 182
PHE A  16
 NAD  A 401 (-3.2A)
None
None
TLA  A 402 ( 3.9A)
NAD  A 401 (-3.3A)
 1.26A 4r7lA-5uibA:
undetectable		 4r7lA-5uibA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 9 VAL A 230
VAL A 228
ILE A 186
PHE A 127
LEU A 179
 None
None
None
None
TLA  A 402 (-4.0A)
 1.46A 5e4dA-5uibA:
undetectable		 5e4dA-5uibA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 4 VAL A 111
GLU A 115
GLY A 316
LEU A 320
 None
 0.87A 5g5gC-5uibA:
undetectable		 5g5gC-5uibA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 6 PHE A 323
SER A 231
VAL A 230
ASP A 178
 None
None
None
TLA  A 402 (-3.4A)
 1.27A 5hesA-5uibA:
undetectable		 5hesA-5uibA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 9 ASN A 222
ASP A 219
VAL A 194
GLY A 151
ILE A 248
 None
 0.93A 5kr0B-5uibA:
undetectable		 5kr0B-5uibA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 PHE A  63
ALA A  59
ILE A  73
SER A  79
GLY A   8
 None
NAD  A 401 ( 4.6A)
None
NAD  A 401 (-2.8A)
None
 1.08A 5m24A-5uibA:
undetectable		 5m24A-5uibA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		4 / 8 HIS A  90
VAL A  92
LEU A  62
ALA A  59
 None
None
None
NAD  A 401 ( 4.6A)
 0.92A 5tt3H-5uibA:
undetectable		 5tt3H-5uibA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 ALA A  74
LEU A  83
VAL A 123
ASP A 106
PHE A 100
 None
 1.24A 5vlmC-5uibA:
undetectable		 5vlmC-5uibA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		3 / 3 THR A 131
GLU A 293
HIS A 289
 None
 0.68A 5xioA-5uibA:
4.7		 5xioA-5uibA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		3 / 3 THR A 131
GLU A 293
HIS A 289
 None
 0.71A 5xiqB-5uibA:
2.1		 5xiqB-5uibA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		3 / 3 THR A 131
GLU A 293
HIS A 289
 None
 0.71A 5xiqD-5uibA:
2.2		 5xiqD-5uibA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.92A 6dgxA-5uibA:
undetectable		 6dgxA-5uibA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 250
VAL A 265
GLY A 143
VAL A 136
ILE A 255
 None
 0.90A 6dh6A-5uibA:
undetectable		 6dh6A-5uibA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_A_LLLA302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 10 ASP A 185
GLY A 316
ASP A 304
THR A 303
SER A 313
 None
 1.21A 6mn1A-5uibA:
undetectable		 6mn1A-5uibA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_B_LLLB302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 5uib OXIDOREDUCTASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 10 ASP A 185
GLY A 316
ASP A 304
THR A 303
SER A 313
 None
 1.27A 6mn1B-5uibA:
undetectable		 6mn1B-5uibA:
14.02