SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uiv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		5 / 12 ILE A  89
GLN A   5
LEU A  82
LEU A 139
ILE A   7
 None
 1.28A 1g5yB-5uivA:
undetectable		 1g5yB-5uivA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		3 / 3 ASP A 146
ASP A 190
LYS A 171
 None
 0.91A 1lqtB-5uivA:
2.3		 1lqtB-5uivA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		3 / 3 ASP A 146
ASP A 190
LYS A 171
 None
 0.90A 1lquB-5uivA:
3.1		 1lquB-5uivA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		4 / 8 SER A  22
LEU A  24
ILE A  88
ILE A  89
 None
 0.84A 1sbrA-5uivA:
undetectable		 1sbrA-5uivA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		5 / 12 LEU A  51
GLU A 159
ARG A  39
SER A  96
TYR A 100
 TMP  A 301 (-4.5A)
TMP  A 301 ( 4.5A)
TMP  A 301 (-3.9A)
TMP  A 301 ( 4.7A)
TMP  A 301 (-3.6A)
 1.42A 3apwB-5uivA:
undetectable		 3apwB-5uivA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		3 / 3 ASN A  53
ASN A  48
GLU A 159
 None
None
TMP  A 301 ( 4.5A)
 0.69A 3kpdC-5uivA:
undetectable		 3kpdC-5uivA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		3 / 3 ASN A  53
ASN A  48
GLU A 159
 None
None
TMP  A 301 ( 4.5A)
 0.82A 3kpdB-5uivA:
undetectable		 3kpdB-5uivA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE
(Candida
albicans) 		4 / 7 GLU A 159
ARG A 160
PHE A  67
PRO A  37
 TMP  A 301 ( 4.5A)
None
TMP  A 301 (-3.1A)
TMP  A 301 ( 4.4A)
 1.32A 3ql6A-5uivA:
undetectable		 3ql6A-5uivA:
20.91