SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uix'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5uix DH576 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 MET H  78
SER H  21
ARG H  19
TRP H  36
 None
 1.42A 2y7pA-5uixH:
undetectable		 2y7pA-5uixH:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5uix DH576 FAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 10 PHE H 139
GLY H 135
THR H 222
VAL H 215
VAL H 224
 None
 1.15A 4jx1B-5uixH:
undetectable		 4jx1B-5uixH:
20.19