SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uiy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5uiy BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 1A
(Homo
sapiens) 		5 / 6 PRO A1453
VAL A1458
VAL A1463
TYR A1466
ASN A1509
 None
 0.69A 5pbeA-5uiyA:
17.4		 5pbeA-5uiyA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5uiy BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 1A
(Homo
sapiens) 		4 / 8 VAL A1458
CYH A1505
TYR A1508
ASN A1509
 None
 0.58A 5y1yA-5uiyA:
15.4		 5y1yA-5uiyA:
28.79