SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_A_ACTA1397_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	5uj5	ADRENODOXIN (Encephalitozoon cuniculi)	3 / 3	PRO A 78 GLY A 94 TYR A 72	None	0.73A	2vouA-5uj5A: undetectable	2vouA-5uj5A: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_A_TOPA200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	5uj5	ADRENODOXIN (Encephalitozoon cuniculi)	5 / 10	ALA A 111 LEU A 67 VAL A 39 LEU A 50 PHE A 22	None	1.21A	3fl9A-5uj5A: undetectable	3fl9A-5uj5A: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_E_TOPE200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	5uj5	ADRENODOXIN (Encephalitozoon cuniculi)	5 / 10	ALA A 111 LEU A 67 VAL A 39 LEU A 50 PHE A 22	None	1.06A	3fl9E-5uj5A: undetectable	3fl9E-5uj5A: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_F_TOPF200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	5uj5	ADRENODOXIN (Encephalitozoon cuniculi)	5 / 10	ALA A 111 LEU A 67 VAL A 39 LEU A 50 PHE A 22	None	1.07A	3fl9F-5uj5A: undetectable	3fl9F-5uj5A: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UXQ_A_0LIA1752_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	5uj5	ADRENODOXIN (Encephalitozoon cuniculi)	4 / 7	VAL A 42 ILE A 18 ALA A 111 ARG A 13	None	0.79A	4uxqA-5uj5A: undetectable	4uxqA-5uj5A: 20.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VOU_A_ACTA1397_0","2,6-DIHYDROXYPYRIDINE HYDROXYLASE","5uj5","ADRENODOXIN","Encephalitozoon cuniculi",3,"PRO A  78;GLY A  94;TYR A  72","None","0.73A","2vouA-5uj5A:undetectable","2vouA-5uj5A:19.37"],["3FL9_A_TOPA200_1","DIHYDROFOLATE REDUCTASE (DHFR)","5uj5","ADRENODOXIN","Encephalitozoon cuniculi",5,"ALA A 111;LEU A  67;VAL A  39;LEU A  50;PHE A  22","None","1.21A","3fl9A-5uj5A:undetectable","3fl9A-5uj5A:24.00"],["3FL9_E_TOPE200_1","DIHYDROFOLATE REDUCTASE (DHFR)","5uj5","ADRENODOXIN","Encephalitozoon cuniculi",5,"ALA A 111;LEU A  67;VAL A  39;LEU A  50;PHE A  22","None","1.06A","3fl9E-5uj5A:undetectable","3fl9E-5uj5A:24.00"],["3FL9_F_TOPF200_1","DIHYDROFOLATE REDUCTASE (DHFR)","5uj5","ADRENODOXIN","Encephalitozoon cuniculi",5,"ALA A 111;LEU A  67;VAL A  39;LEU A  50;PHE A  22","None","1.07A","3fl9F-5uj5A:undetectable","3fl9F-5uj5A:24.00"],["4UXQ_A_0LIA1752_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","5uj5","ADRENODOXIN","Encephalitozoon cuniculi",4,"VAL A  42;ILE A  18;ALA A 111;ARG A  13","None","0.79A","4uxqA-5uj5A:undetectable","4uxqA-5uj5A:20.45"]]