SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 9 GLU C  59
ILE A 705
GLU A 731
ALA A 729
VAL A 746
 None
 1.30A 1ctrA-5uj7C:
undetectable		 1ctrA-5uj7C:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		4 / 7 THR E  39
GLY E  37
LEU E 157
LYS E 126
 ATP  E 301 (-3.9A)
None
None
ATP  E 301 ( 3.7A)
 0.87A 1gtiD-5uj7E:
undetectable		 1gtiD-5uj7E:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 7 GLN C 181
ASP C 178
LEU C 140
SER C  62
 None
 1.23A 1ig3A-5uj7C:
undetectable
1ig3B-5uj7C:
undetectable		 1ig3A-5uj7C:
21.25
1ig3B-5uj7C:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 12 GLY C 191
ASP C 159
ALA C 188
SER C  62
LEU C  84
 None
MG  C 502 (-3.6A)
None
None
None
 1.38A 1kiaD-5uj7C:
undetectable		 1kiaD-5uj7C:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A 573
VAL A 649
LEU A 617
LEU A 625
LEU A 636
 None
 1.20A 1mx1C-5uj7A:
2.4		 1mx1C-5uj7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		3 / 3 GLU E  24
HIS E  26
HIS E  27
 None
 0.72A 1oe2A-5uj7E:
undetectable		 1oe2A-5uj7E:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 4 ASP C 197
LEU C 202
LEU C 199
LEU C 201
 None
 1.39A 1u18A-5uj7C:
undetectable		 1u18A-5uj7C:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 11 ARG A 727
GLU C  59
GLU A 731
ILE C 155
HIS C 216
 None
 0.79A 1vhwA-5uj7A:
undetectable
1vhwD-5uj7A:
undetectable		 1vhwA-5uj7A:
20.00
1vhwD-5uj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 11 ARG A 727
GLU C  59
GLU A 731
ILE C 155
HIS C 216
 None
 0.79A 1vhwC-5uj7A:
undetectable
1vhwE-5uj7A:
undetectable		 1vhwC-5uj7A:
20.00
1vhwE-5uj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 11 HIS C 216
ARG A 727
GLU C  59
GLU A 731
ILE C 155
 None
 0.80A 1vhwA-5uj7C:
undetectable
1vhwD-5uj7C:
undetectable		 1vhwA-5uj7C:
18.64
1vhwD-5uj7C:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 11 HIS C 216
ARG A 727
GLU C  59
GLU A 731
ILE C 155
 None
 0.80A 1vhwC-5uj7C:
undetectable
1vhwE-5uj7C:
undetectable		 1vhwC-5uj7C:
18.64
1vhwE-5uj7C:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens;
Homo
sapiens) 		4 / 4 LEU E 177
SER E  16
LEU C 285
LEU C 308
 None
 1.14A 1yajA-5uj7E:
2.9		 1yajA-5uj7E:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens;
Homo
sapiens) 		4 / 5 LEU E 177
SER E  16
LEU C 285
LEU C 308
 None
 1.10A 1yajD-5uj7E:
2.3		 1yajD-5uj7E:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 10 LEU C 173
ALA C 165
ILE C 198
LEU C 201
LEU C  64
 None
 1.11A 1yi4A-5uj7C:
undetectable		 1yi4A-5uj7C:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU E 187
ALA E 229
LEU E 228
LEU E 212
VAL E 214
 None
 1.06A 2c12C-5uj7E:
undetectable		 2c12C-5uj7E:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 7 LEU C 136
PHE C 177
ILE C 114
PHE C 156
 None
 0.89A 2opxA-5uj7C:
2.5		 2opxA-5uj7C:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 ARG A 720
ARG A 721
PRO A 536
 ATP  A 900 (-3.9A)
None
ATP  A 900 (-4.0A)
 1.00A 2wljA-5uj7A:
undetectable		 2wljA-5uj7A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 10 VAL A 746
ILE A 705
LEU A 723
LEU A 694
ALA A 499
 None
 0.83A 2xf3A-5uj7A:
undetectable		 2xf3A-5uj7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 7 ILE C 190
GLY C 191
PHE C 161
PHE C 177
 None
 0.83A 2y7wC-5uj7C:
undetectable		 2y7wC-5uj7C:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A 826
LEU A 778
VAL A 772
THR A 819
PHE A 795
 None
 1.35A 2yloA-5uj7A:
undetectable		 2yloA-5uj7A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		4 / 8 ALA E 206
TYR E 236
ILE E 208
HIS E 195
 None
 1.06A 2zmaA-5uj7E:
undetectable		 2zmaA-5uj7E:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		6 / 12 LEU C  99
LEU C 140
ASN C 135
ILE C 187
ALA C 188
THR C  54
 None
 1.50A 3a50D-5uj7C:
undetectable		 3a50D-5uj7C:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 MET A 758
VAL A 712
GLU A 753
 None
 0.68A 3c6gA-5uj7A:
undetectable		 3c6gA-5uj7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 GLU A 546
VAL A 547
CYH A 550
 None
 0.97A 3fbxA-5uj7A:
undetectable		 3fbxA-5uj7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		4 / 7 TYR E 199
VAL E 214
ILE E 208
ARG E 255
 None
 1.05A 3mssB-5uj7E:
undetectable		 3mssB-5uj7E:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 9 GLY E 213
GLU E 258
LEU E 211
LEU E 212
ILE E 208
 None
 1.37A 3nbqA-5uj7E:
undetectable		 3nbqA-5uj7E:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		3 / 3 TYR C 418
MET C 332
LEU C 379
 None
 0.97A 3vw1D-5uj7C:
2.5		 3vw1D-5uj7C:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 6 ASP C 107
THR C 115
ILE C 114
THR C 171
 None
 1.01A 4acbC-5uj7C:
undetectable		 4acbC-5uj7C:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 8 ALA C 188
THR C  54
LEU C  84
LEU C  81
 None
 0.81A 4ejgB-5uj7C:
undetectable		 4ejgB-5uj7C:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens;
Homo
sapiens) 		4 / 4 ILE A 532
SER A 533
ASP A 620
ASP C 178
 None
None
MG  A 901 (-2.1A)
None
 1.37A 4krhB-5uj7A:
undetectable		 4krhB-5uj7A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens;
Homo
sapiens) 		3 / 3 LYS E 164
ASN E 168
ASP A 840
 None
 0.63A 4o1eA-5uj7E:
undetectable		 4o1eA-5uj7E:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 10 LEU E 144
LEU E 130
LEU E  72
ILE E  76
LEU E  73
 None
 0.99A 4odoA-5uj7E:
undetectable		 4odoA-5uj7E:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 10 LEU E 144
LEU E 130
LEU E  72
ILE E  76
LEU E  73
 None
 1.05A 4odoB-5uj7E:
undetectable		 4odoB-5uj7E:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 10 LEU E 144
LEU E 130
LEU E  72
ILE E  76
LEU E  73
 None
 1.08A 4odoC-5uj7E:
undetectable		 4odoC-5uj7E:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU E 144
LEU E 130
LEU E  72
ILE E  76
LEU E  73
 None
 1.00A 4odrA-5uj7E:
undetectable
4odrB-5uj7E:
undetectable		 4odrA-5uj7E:
16.37
4odrB-5uj7E:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 11 LEU E 144
LEU E 130
LEU E  72
ILE E  76
LEU E  73
 None
 1.05A 4odrA-5uj7E:
undetectable
4odrB-5uj7E:
undetectable		 4odrA-5uj7E:
16.37
4odrB-5uj7E:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 7 THR C 193
LEU C 217
ASN C 219
SER A 828
 None
 1.12A 4pfjA-5uj7C:
undetectable		 4pfjA-5uj7C:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		4 / 5 LEU C 111
LEU C  99
PHE C 132
LEU C 176
 None
 1.02A 5gtrA-5uj7C:
undetectable		 5gtrA-5uj7C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU E 124
PHE E 156
ILE E  35
ARG E  11
ALA E 127
 None
 0.95A 5h5fA-5uj7E:
undetectable		 5h5fA-5uj7E:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU E 124
PHE E 156
ILE E  35
GLY E  37
ALA E 127
 None
 1.08A 5h5fA-5uj7E:
undetectable		 5h5fA-5uj7E:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 GLY A 534
GLN A 679
LYS A 540
 None
None
ATP  A 900 (-3.0A)
 0.87A 5imsB-5uj7A:
undetectable		 5imsB-5uj7A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 ASN A 848
TYR A 763
CYH A 829
 None
 0.96A 5lsuB-5uj7A:
undetectable		 5lsuB-5uj7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		3 / 3 MET C 412
GLN C 416
ARG C 426
 None
 1.13A 5m35B-5uj7C:
undetectable		 5m35B-5uj7C:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		5 / 12 LEU C 172
LEU C 158
ILE C 187
LEU C 136
LEU C 118
 None
 1.17A 5og9B-5uj7C:
undetectable		 5og9B-5uj7C:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		3 / 3 MET C 412
GLN C 416
ARG C 426
 None
 1.13A 6fn9A-5uj7C:
undetectable		 6fn9A-5uj7C:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens) 		3 / 3 MET C 412
GLN C 416
ARG C 426
 None
 1.14A 6fnaB-5uj7C:
undetectable		 6fnaB-5uj7C:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 THR A 765
GLU A 774
ASN C 219
 None
 0.82A 6nj9K-5uj7A:
undetectable		 6nj9K-5uj7A:
23.45