SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DB1_A_VDXA428_1 (VITAMIN D NUCLEAR RECEPTOR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	LEU A1243 LEU A1246 VAL A1247 SER A1250 VAL A1205	None	1.16A	1db1A-5ujaA: undetectable	1db1A-5ujaA: 11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	LEU A1243 LEU A1246 VAL A1247 SER A1250 VAL A1205	None	1.12A	1ie9A-5ujaA: undetectable	1ie9A-5ujaA: 11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	VAL A1233 SER A1234 SER A 996 VAL A 353 LEU A1224	None	1.38A	1ie9A-5ujaA: undetectable	1ie9A-5ujaA: 11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	TRP A 223 MET A 228 ARG A1201 VAL A1193	None	1.48A	1p6kA-5ujaA: undetectable 1p6kB-5ujaA: undetectable	1p6kA-5ujaA: 14.67 1p6kB-5ujaA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QVT_A_PRLA311_0 (TRANSCRIPTIONAL REGULATOR QACR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 8	LEU A1452 THR A1494 TYR A1493 ILE A1471	None	1.09A	1qvtA-5ujaA: 3.6	1qvtA-5ujaA: 9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U70_A_MTXA187_2 (DIHYDROFOLATE REDUCTASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	SER A 604 ILE A 603 VAL A 477 THR A 556	None	1.16A	1u70A-5ujaA: undetectable	1u70A-5ujaA: 8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_A_STRA1001_2 (MINERALOCORTICOID RECEPTOR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	LEU A 455 LEU A 588 SER A 585 LEU A 462	None	1.13A	1ya3A-5ujaA: undetectable	1ya3A-5ujaA: 10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_D_SALD5006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 5	PHE A1216 THR A1111 LEU A1108 ALA A1213	None	1.17A	2e1qD-5ujaA: undetectable	2e1qD-5ujaA: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8L_A_SAMA400_1 (HYPOTHETICAL PROTEIN LMO1582)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	THR A1489 THR A1482 ASP A1453 ASP A1375	None	1.40A	2f8lA-5ujaA: undetectable	2f8lA-5ujaA: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	THR A 999 ILE A 350 ASP A1000 SER A 996	None	1.22A	2xytI-5ujaA: undetectable	2xytI-5ujaA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBU_D_ADND504_1 (UNCHARACTERIZED CONSERVED PROTEIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	PHE A 329 ASN A 442 PHE A 325	None	1.07A	2zbuD-5ujaA: undetectable	2zbuD-5ujaA: 11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_2 (CYTOCHROME P450 2R1)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	LEU A 753 GLU A 760 ILE A 761	None	0.58A	3czhA-5ujaA: undetectable	3czhA-5ujaA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_B_VIBB223_1 (THIAMINE PYROPHOSPHOKINASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	LEU A 241 LEU A1139 SER A1144 THR A1255	None	0.97A	3lm8B-5ujaA: undetectable 3lm8D-5ujaA: undetectable	3lm8B-5ujaA: 9.09 3lm8D-5ujaA: 9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_B_NIMB1701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	VAL A 254 VAL A1181 SER A1177	None	0.74A	3n8xB-5ujaA: undetectable	3n8xB-5ujaA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDI_A_SAMA601_0 (METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	GLU A1349 ILE A1350 PHE A1294 ALA A1358 ILE A1352	None	1.37A	3ndiA-5ujaA: undetectable	3ndiA-5ujaA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NK7_B_SAMB770_0 (23S RRNA METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ASN A 725 GLY A 770 ILE A 806 LEU A 778 VAL A 776	None	0.98A	3nk7B-5ujaA: undetectable	3nk7B-5ujaA: 10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9L_A_CAMA1419_0 (CYTOCHROME P450)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ILE A 726 LEU A 750 LEU A 753 GLY A 756 ILE A 761	None	0.99A	4c9lA-5ujaA: undetectable	4c9lA-5ujaA: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9L_B_CAMB1419_0 (CYTOCHROME P450)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ILE A 726 LEU A 750 LEU A 753 GLY A 756 ILE A 761	None	0.97A	4c9lB-5ujaA: undetectable	4c9lB-5ujaA: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9O_A_CAMA423_0 (CYTOCHROME P450)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ILE A 726 LEU A 750 LEU A 753 GLY A 756 ILE A 761	None	1.04A	4c9oA-5ujaA: undetectable	4c9oA-5ujaA: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9O_B_CAMB423_0 (CYTOCHROME P450)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ILE A 726 LEU A 750 LEU A 753 GLY A 756 ILE A 761	None	1.04A	4c9oB-5ujaA: undetectable	4c9oB-5ujaA: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D31_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	MET A 228 ARG A1201 VAL A1193 TRP A 223	None	1.50A	4d31A-5ujaA: undetectable 4d31B-5ujaA: undetectable	4d31A-5ujaA: 14.93 4d31B-5ujaA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DR2_A_PARA1609_1 (16S RRNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	TYR A1151 ARG A1147 SER A1148	None	0.88A	4dr2I-5ujaA: undetectable 4dr2J-5ujaA: undetectable	4dr2I-5ujaA: 7.20 4dr2J-5ujaA: 5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DT8_A_ADNA401_1 (APH(2'')-ID)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 11	SER A1236 ILE A1107 ILE A1118 LEU A1121 ILE A1117	None	1.00A	4dt8A-5ujaA: undetectable	4dt8A-5ujaA: 10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	ARG A1262 PRO A1149 SER A1152 VAL A1145	None	1.25A	4klrA-5ujaA: undetectable	4klrA-5ujaA: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF7_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	TYR A1151 ARG A1147 SER A1148	None	0.96A	4lf7I-5ujaA: undetectable 4lf7J-5ujaA: undetectable	4lf7I-5ujaA: 7.20 4lf7J-5ujaA: 5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF8_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	TYR A1151 ARG A1147 SER A1148	None	0.96A	4lf8I-5ujaA: undetectable 4lf8J-5ujaA: undetectable	4lf8I-5ujaA: 7.20 4lf8J-5ujaA: 5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLT_B_GCSB303_1 (CHITOSANASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 6	ILE A1483 ASP A1453 GLY A1331 HIS A1485	None	1.02A	4oltB-5ujaA: undetectable	4oltB-5ujaA: 11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYK_A_OAQA302_0 (SULFOTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ILE A 395 LEU A 317 VAL A 254 PHE A 321 THR A 320	None	1.30A	5bykA-5ujaA: undetectable	5bykA-5ujaA: 10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECK_A_ILEA601_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 6	ALA A1457 THR A1456 VAL A1459 HIS A1485	None	0.93A	5eckA-5ujaA: undetectable	5eckA-5ujaA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECK_D_ILED601_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 6	ALA A1457 THR A1456 VAL A1459 HIS A1485	None	0.93A	5eckD-5ujaA: undetectable	5eckD-5ujaA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECL_A_ILEA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 6	ALA A1457 THR A1456 VAL A1459 HIS A1485	None	0.95A	5eclA-5ujaA: undetectable	5eclA-5ujaA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	MET A 228 ARG A1201 VAL A1193 TRP A 223	None	1.45A	5fvsA-5ujaA: undetectable 5fvsB-5ujaA: undetectable	5fvsA-5ujaA: 14.93 5fvsB-5ujaA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	MET A 228 ARG A1201 VAL A1193 TRP A 223	None	1.49A	5fvtA-5ujaA: undetectable 5fvtB-5ujaA: undetectable	5fvtA-5ujaA: 14.93 5fvtB-5ujaA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0R_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	SER A1225 ALA A1226 GLN A 580 THR A 999	None	1.42A	5n0rA-5ujaA: undetectable	5n0rA-5ujaA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	SER A1225 ALA A1226 GLN A 580 THR A 999	None	1.41A	5n0sA-5ujaA: undetectable	5n0sA-5ujaA: 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0W_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	SER A1225 ALA A1226 GLN A 580 THR A 999	None	1.44A	5n0wA-5ujaA: undetectable	5n0wA-5ujaA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0X_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 4	SER A1225 ALA A1226 GLN A 580 THR A 999	None	1.42A	5n0xA-5ujaA: undetectable	5n0xA-5ujaA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U63_A_ACTA406_0 (THIOREDOXIN REDUCTASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	3 / 3	HIS A 494 SER A 497 ARG A 532	None	1.01A	5u63A-5ujaA: undetectable	5u63A-5ujaA: 13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UJX_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	5 / 12	ALA A 797 LEU A 778 ILE A 811 ARG A 822 LEU A 824	None	1.06A	5ujxB-5ujaA: 3.2	5ujxB-5ujaA: 7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 7	MET A 228 ARG A1201 VAL A1193 TRP A 223	None	1.50A	6auvA-5ujaA: undetectable 6auvB-5ujaA: undetectable	6auvA-5ujaA: 5.72 6auvB-5ujaA: 5.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	5uja	BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 8	TYR A 568 PHE A 565 PHE A 589 SER A 465	None	1.05A	6huoC-5ujaA: 2.5 6huoD-5ujaA: 1.0	6huoC-5ujaA: 4.08 6huoD-5ujaA: 4.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DB1_A_VDXA428_1","VITAMIN D NUCLEAR RECEPTOR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"LEU A1243;LEU A1246;VAL A1247;SER A1250;VAL A1205","None","1.16A","1db1A-5ujaA:undetectable","1db1A-5ujaA:11.08"],["1IE9_A_VDXA500_1","VITAMIN D3 RECEPTOR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"LEU A1243;LEU A1246;VAL A1247;SER A1250;VAL A1205","None","1.12A","1ie9A-5ujaA:undetectable","1ie9A-5ujaA:11.08"],["1IE9_A_VDXA500_1","VITAMIN D3 RECEPTOR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"VAL A1233;SER A1234;SER A 996;VAL A 353;LEU A1224","None","1.38A","1ie9A-5ujaA:undetectable","1ie9A-5ujaA:11.08"],["1P6K_B_H4BB761_1","NITRIC-OXIDE SYNTHASE, BRAIN;NITRIC-OXIDE SYNTHASE, BRAIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"TRP A 223;MET A 228;ARG A1201;VAL A1193","None","1.48A","1p6kA-5ujaA:undetectable;1p6kB-5ujaA:undetectable","1p6kA-5ujaA:14.67;1p6kB-5ujaA:14.67"],["1QVT_A_PRLA311_0","TRANSCRIPTIONAL REGULATOR QACR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"LEU A1452;THR A1494;TYR A1493;ILE A1471","None","1.09A","1qvtA-5ujaA:3.6","1qvtA-5ujaA:9.77"],["1U70_A_MTXA187_2","DIHYDROFOLATE REDUCTASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"SER A 604;ILE A 603;VAL A 477;THR A 556","None","1.16A","1u70A-5ujaA:undetectable","1u70A-5ujaA:8.94"],["1YA3_A_STRA1001_2","MINERALOCORTICOID RECEPTOR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"LEU A 455;LEU A 588;SER A 585;LEU A 462","None","1.13A","1ya3A-5ujaA:undetectable","1ya3A-5ujaA:10.83"],["2E1Q_D_SALD5006_1","XANTHINE DEHYDROGENASE\/OXIDASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"PHE A1216;THR A1111;LEU A1108;ALA A1213","None","1.17A","2e1qD-5ujaA:undetectable","2e1qD-5ujaA:20.97"],["2F8L_A_SAMA400_1","HYPOTHETICAL PROTEIN LMO1582","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"THR A1489;THR A1482;ASP A1453;ASP A1375","None","1.40A","2f8lA-5ujaA:undetectable","2f8lA-5ujaA:12.66"],["2XYT_H_TC9H1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"THR A 999;ILE A 350;ASP A1000;SER A 996","None","1.22A","2xytI-5ujaA:undetectable","2xytI-5ujaA:10.31"],["2ZBU_D_ADND504_1","UNCHARACTERIZED CONSERVED PROTEIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"PHE A 329;ASN A 442;PHE A 325","None","1.07A","2zbuD-5ujaA:undetectable","2zbuD-5ujaA:11.20"],["3CZH_A_D2VA602_2","CYTOCHROME P450 2R1","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"LEU A 753;GLU A 760;ILE A 761","None","0.58A","3czhA-5ujaA:undetectable","3czhA-5ujaA:16.08"],["3LM8_B_VIBB223_1","THIAMINE PYROPHOSPHOKINASE;THIAMINE PYROPHOSPHOKINASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"LEU A 241;LEU A1139;SER A1144;THR A1255","None","0.97A","3lm8B-5ujaA:undetectable;3lm8D-5ujaA:undetectable","3lm8B-5ujaA:9.09;3lm8D-5ujaA:9.09"],["3N8X_B_NIMB1701_2","PROSTAGLANDIN G\/H SYNTHASE 1","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"VAL A 254;VAL A1181;SER A1177","None","0.74A","3n8xB-5ujaA:undetectable","3n8xB-5ujaA:16.29"],["3NDI_A_SAMA601_0","METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"GLU A1349;ILE A1350;PHE A1294;ALA A1358;ILE A1352","None","1.37A","3ndiA-5ujaA:undetectable","3ndiA-5ujaA:13.97"],["3NK7_B_SAMB770_0","23S RRNA METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ASN A 725;GLY A 770;ILE A 806;LEU A 778;VAL A 776","None","0.98A","3nk7B-5ujaA:undetectable","3nk7B-5ujaA:10.53"],["4C9L_A_CAMA1419_0","CYTOCHROME P450","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ILE A 726;LEU A 750;LEU A 753;GLY A 756;ILE A 761","None","0.99A","4c9lA-5ujaA:undetectable","4c9lA-5ujaA:16.04"],["4C9L_B_CAMB1419_0","CYTOCHROME P450","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ILE A 726;LEU A 750;LEU A 753;GLY A 756;ILE A 761","None","0.97A","4c9lB-5ujaA:undetectable","4c9lB-5ujaA:16.04"],["4C9O_A_CAMA423_0","CYTOCHROME P450","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ILE A 726;LEU A 750;LEU A 753;GLY A 756;ILE A 761","None","1.04A","4c9oA-5ujaA:undetectable","4c9oA-5ujaA:16.04"],["4C9O_B_CAMB423_0","CYTOCHROME P450","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ILE A 726;LEU A 750;LEU A 753;GLY A 756;ILE A 761","None","1.04A","4c9oB-5ujaA:undetectable","4c9oB-5ujaA:16.04"],["4D31_A_H4BA760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"MET A 228;ARG A1201;VAL A1193;TRP A 223","None","1.50A","4d31A-5ujaA:undetectable;4d31B-5ujaA:undetectable","4d31A-5ujaA:14.93;4d31B-5ujaA:14.93"],["4DR2_A_PARA1609_1","16S RRNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"TYR A1151;ARG A1147;SER A1148","None","0.88A","4dr2I-5ujaA:undetectable;4dr2J-5ujaA:undetectable","4dr2I-5ujaA:7.20;4dr2J-5ujaA:5.76"],["4DT8_A_ADNA401_1","APH(2'')-ID","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"SER A1236;ILE A1107;ILE A1118;LEU A1121;ILE A1117","None","1.00A","4dt8A-5ujaA:undetectable","4dt8A-5ujaA:10.89"],["4KLR_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ARG A1262;PRO A1149;SER A1152;VAL A1145","None","1.25A","4klrA-5ujaA:undetectable","4klrA-5ujaA:13.53"],["4LF7_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"TYR A1151;ARG A1147;SER A1148","None","0.96A","4lf7I-5ujaA:undetectable;4lf7J-5ujaA:undetectable","4lf7I-5ujaA:7.20;4lf7J-5ujaA:5.76"],["4LF8_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"TYR A1151;ARG A1147;SER A1148","None","0.96A","4lf8I-5ujaA:undetectable;4lf8J-5ujaA:undetectable","4lf8I-5ujaA:7.20;4lf8J-5ujaA:5.76"],["4OLT_B_GCSB303_1","CHITOSANASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ILE A1483;ASP A1453;GLY A1331;HIS A1485","None","1.02A","4oltB-5ujaA:undetectable","4oltB-5ujaA:11.14"],["5BYK_A_OAQA302_0","SULFOTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ILE A 395;LEU A 317;VAL A 254;PHE A 321;THR A 320","None","1.30A","5bykA-5ujaA:undetectable","5bykA-5ujaA:10.22"],["5ECK_A_ILEA601_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ALA A1457;THR A1456;VAL A1459;HIS A1485","None","0.93A","5eckA-5ujaA:undetectable","5eckA-5ujaA:16.90"],["5ECK_D_ILED601_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ALA A1457;THR A1456;VAL A1459;HIS A1485","None","0.93A","5eckD-5ujaA:undetectable","5eckD-5ujaA:16.90"],["5ECL_A_ILEA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ALA A1457;THR A1456;VAL A1459;HIS A1485","None","0.95A","5eclA-5ujaA:undetectable","5eclA-5ujaA:16.90"],["5FVS_A_H4BA760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"MET A 228;ARG A1201;VAL A1193;TRP A 223","None","1.45A","5fvsA-5ujaA:undetectable;5fvsB-5ujaA:undetectable","5fvsA-5ujaA:14.93;5fvsB-5ujaA:14.93"],["5FVT_A_H4BA760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"MET A 228;ARG A1201;VAL A1193;TRP A 223","None","1.49A","5fvtA-5ujaA:undetectable;5fvtB-5ujaA:undetectable","5fvtA-5ujaA:14.93;5fvtB-5ujaA:14.93"],["5N0R_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"SER A1225;ALA A1226;GLN A 580;THR A 999","None","1.42A","5n0rA-5ujaA:undetectable","5n0rA-5ujaA:14.96"],["5N0S_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"SER A1225;ALA A1226;GLN A 580;THR A 999","None","1.41A","5n0sA-5ujaA:undetectable","5n0sA-5ujaA:15.19"],["5N0W_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"SER A1225;ALA A1226;GLN A 580;THR A 999","None","1.44A","5n0wA-5ujaA:undetectable","5n0wA-5ujaA:14.96"],["5N0X_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"SER A1225;ALA A1226;GLN A 580;THR A 999","None","1.42A","5n0xA-5ujaA:undetectable","5n0xA-5ujaA:14.96"],["5U63_A_ACTA406_0","THIOREDOXIN REDUCTASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",3,"HIS A 494;SER A 497;ARG A 532","None","1.01A","5u63A-5ujaA:undetectable","5u63A-5ujaA:13.77"],["5UJX_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",5,"ALA A 797;LEU A 778;ILE A 811;ARG A 822;LEU A 824","None","1.06A","5ujxB-5ujaA:3.2","5ujxB-5ujaA:7.00"],["6AUV_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"MET A 228;ARG A1201;VAL A1193;TRP A 223","None","1.50A","6auvA-5ujaA:undetectable;6auvB-5ujaA:undetectable","6auvA-5ujaA:5.72;6auvB-5ujaA:5.72"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","5uja","BOVINE MULTIDRUG RESISTANCE PROTEIN 1 (MRP1),MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"TYR A 568;PHE A 565;PHE A 589;SER A 465","None","1.05A","6huoC-5ujaA:2.5;6huoD-5ujaA:1.0","6huoC-5ujaA:4.08;6huoD-5ujaA:4.99"]]