SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ujd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		5 / 9 GLN A 191
VAL A 190
ASP A  17
ILE A  16
VAL A  46
 None
 1.34A 3fi0L-5ujdA:
undetectable		 3fi0L-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		3 / 3 TYR A 152
TYR A 178
GLU A  23
 None
 0.91A 3pfgA-5ujdA:
undetectable		 3pfgA-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		4 / 5 ASP A 170
LEU A 169
ILE A  93
PRO A  94
 None
 1.16A 3s3vA-5ujdA:
undetectable		 3s3vA-5ujdA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		4 / 5 VAL A 149
SER A 153
GLY A 199
ARG A 160
 None
 1.45A 3v4tA-5ujdA:
undetectable
3v4tD-5ujdA:
undetectable		 3v4tA-5ujdA:
undetectable
3v4tD-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		4 / 6 VAL A 214
LEU A 212
LEU A  10
MET A  64
 None
 1.06A 4o1zA-5ujdA:
undetectable		 4o1zA-5ujdA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		5 / 12 VAL A  47
LEU A 181
ILE A 186
ILE A 183
VAL A 200
 None
 1.25A 4y0pA-5ujdA:
undetectable		 4y0pA-5ujdA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		5 / 12 ILE A 183
VAL A 190
VAL A 189
MET A  55
THR A  49
 None
 1.01A 5bykA-5ujdA:
undetectable		 5bykA-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		5 / 12 ASN A  95
SER A 155
SER A 151
GLY A 101
THR A 103
 None
 1.47A 5oj0A-5ujdA:
undetectable		 5oj0A-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		3 / 3 THR A 122
MET A 176
HIS A  90
 None
 0.85A 5uunA-5ujdA:
undetectable		 5uunA-5ujdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ujd SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNI
(Staphylococcus
pseudintermedius) 		3 / 3 GLY A 184
VAL A  47
MET A  55
 None
 0.48A 5ycpA-5ujdA:
undetectable		 5ycpA-5ujdA:
21.95