SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
6 / 12 THR A 321
THR A 358
ILE A 349
ALA A 328
ALA A 371
ILE A 372
None
1.23A 1bx4A-5ujuA:
undetectable
1bx4A-5ujuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.47A 1c9sA-5ujuA:
undetectable
1c9sK-5ujuA:
undetectable
1c9sA-5ujuA:
8.35
1c9sK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.46A 1c9sA-5ujuA:
undetectable
1c9sB-5ujuA:
undetectable
1c9sA-5ujuA:
8.35
1c9sB-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.47A 1c9sC-5ujuA:
undetectable
1c9sD-5ujuA:
undetectable
1c9sC-5ujuA:
8.35
1c9sD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 1c9sD-5ujuA:
undetectable
1c9sE-5ujuA:
undetectable
1c9sD-5ujuA:
8.35
1c9sE-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.46A 1c9sE-5ujuA:
undetectable
1c9sF-5ujuA:
undetectable
1c9sE-5ujuA:
8.35
1c9sF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.49A 1c9sF-5ujuA:
undetectable
1c9sG-5ujuA:
undetectable
1c9sF-5ujuA:
8.35
1c9sG-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 1c9sG-5ujuA:
undetectable
1c9sH-5ujuA:
undetectable
1c9sG-5ujuA:
8.35
1c9sH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 1c9sH-5ujuA:
undetectable
1c9sI-5ujuA:
undetectable
1c9sH-5ujuA:
8.35
1c9sI-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 1c9sJ-5ujuA:
undetectable
1c9sK-5ujuA:
undetectable
1c9sJ-5ujuA:
8.35
1c9sK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.43A 1c9sL-5ujuA:
undetectable
1c9sM-5ujuA:
undetectable
1c9sL-5ujuA:
8.35
1c9sM-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 8 SER A 115
ILE A 118
LEU A 119
LEU A 221
None
0.88A 1eupA-5ujuA:
0.0
1eupA-5ujuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 GLN A 463
ILE A 490
HIS A 494
None
0.72A 1fm9A-5ujuA:
undetectable
1fm9A-5ujuA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.46A 1gtfA-5ujuA:
undetectable
1gtfK-5ujuA:
undetectable
1gtfA-5ujuA:
8.35
1gtfK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.47A 1gtfA-5ujuA:
undetectable
1gtfB-5ujuA:
undetectable
1gtfA-5ujuA:
8.35
1gtfB-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.46A 1gtfE-5ujuA:
undetectable
1gtfF-5ujuA:
undetectable
1gtfE-5ujuA:
8.35
1gtfF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.46A 1gtfF-5ujuA:
undetectable
1gtfG-5ujuA:
undetectable
1gtfF-5ujuA:
8.35
1gtfG-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 1gtfI-5ujuA:
undetectable
1gtfJ-5ujuA:
undetectable
1gtfI-5ujuA:
8.35
1gtfJ-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 7 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.44A 1gtfL-5ujuA:
undetectable
1gtfM-5ujuA:
undetectable
1gtfL-5ujuA:
8.35
1gtfM-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.46A 1gtfM-5ujuA:
undetectable
1gtfN-5ujuA:
undetectable
1gtfM-5ujuA:
8.35
1gtfN-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 8 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 1gtfN-5ujuA:
undetectable
1gtfO-5ujuA:
undetectable
1gtfN-5ujuA:
8.35
1gtfO-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 1gtfO-5ujuA:
undetectable
1gtfP-5ujuA:
undetectable
1gtfO-5ujuA:
8.35
1gtfP-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.46A 1gtfP-5ujuA:
undetectable
1gtfQ-5ujuA:
undetectable
1gtfP-5ujuA:
8.35
1gtfQ-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.49A 1gtnG-5ujuA:
undetectable
1gtnH-5ujuA:
undetectable
1gtnG-5ujuA:
8.35
1gtnH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.44A 1gtnO-5ujuA:
undetectable
1gtnP-5ujuA:
undetectable
1gtnO-5ujuA:
8.35
1gtnP-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.47A 1gtnR-5ujuA:
undetectable
1gtnS-5ujuA:
undetectable
1gtnR-5ujuA:
8.35
1gtnS-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 GLN A 463
ILE A 490
HIS A 494
None
0.71A 1k74A-5ujuA:
undetectable
1k74A-5ujuA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 PHE A 141
PRO A  33
ALA A 130
PHE A 127
None
1.15A 1lqtA-5ujuA:
3.1
1lqtA-5ujuA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 PHE A 141
PRO A  33
ALA A 130
PHE A 127
None
1.15A 1lquA-5ujuA:
2.1
1lquA-5ujuA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.46A 1utdA-5ujuA:
undetectable
1utdB-5ujuA:
undetectable
1utdA-5ujuA:
8.35
1utdB-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.46A 1utdD-5ujuA:
undetectable
1utdE-5ujuA:
undetectable
1utdD-5ujuA:
8.35
1utdE-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.44A 1utdG-5ujuA:
undetectable
1utdH-5ujuA:
undetectable
1utdG-5ujuA:
8.35
1utdH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.48A 1utdA-5ujuA:
undetectable
1utdK-5ujuA:
undetectable
1utdA-5ujuA:
8.35
1utdK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.44A 1utdN-5ujuA:
undetectable
1utdO-5ujuA:
undetectable
1utdN-5ujuA:
8.35
1utdO-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 1utdR-5ujuA:
undetectable
1utdS-5ujuA:
undetectable
1utdR-5ujuA:
8.35
1utdS-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 LEU A 167
ILE A 194
VAL A 195
ASN A 225
TRP A 164
None
1.27A 1wsvB-5ujuA:
undetectable
1wsvB-5ujuA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 ILE A 112
ALA A 222
LEU A  17
ILE A  20
PHE A   6
None
1.28A 1y0xX-5ujuA:
undetectable
1y0xX-5ujuA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 THR A 199
GLN A 100
PHE A 218
LEU A 217
VAL A 114
None
1.06A 2g72B-5ujuA:
2.7
2g72B-5ujuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 ILE A 129
TYR A 214
LEU A 217
PHE A 218
LEU A 221
None
1.00A 2mjiA-5ujuA:
undetectable
2mjiA-5ujuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 LEU A 119
PHE A 218
LEU A 157
ILE A 245
SER A  27
None
1.37A 2pnjB-5ujuA:
2.4
2pnjB-5ujuA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 6 ILE A 118
ARG A 121
LEU A 122
LEU A 250
None
1.06A 2rlfA-5ujuA:
undetectable
2rlfD-5ujuA:
undetectable
2rlfA-5ujuA:
5.05
2rlfD-5ujuA:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 TRP A 164
GLN A 166
TRP A 103
None
1.27A 2vqyA-5ujuA:
undetectable
2vqyA-5ujuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ILE A 390
GLY A 391
TYR A 338
PRO A 431
ILE A 393
None
1.38A 2y7pA-5ujuA:
undetectable
2y7pA-5ujuA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 ALA A  96
ALA A  95
ALA A  99
GLN A  62
None
0.72A 3a2qA-5ujuA:
undetectable
3a2qA-5ujuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 11 ALA A 240
ARG A 244
ILE A 236
LEU A 262
ALA A 264
None
1.23A 3kw2A-5ujuA:
3.6
3kw2A-5ujuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 11 ALA A 240
ARG A 244
ILE A 236
LEU A 262
ALA A 264
None
1.28A 3kw2B-5ujuA:
3.4
3kw2B-5ujuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A  96
LEU A 263
ALA A  64
VAL A  69
THR A 265
None
1.42A 3r9cA-5ujuA:
undetectable
3r9cA-5ujuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 6 LEU A 413
ALA A 332
LEU A 379
THR A 380
None
1.04A 3rozA-5ujuA:
4.2
3rozA-5ujuA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 11 ASN A 123
GLN A 153
PHE A 145
GLY A 149
GLY A  42
None
1.42A 3v3oC-5ujuA:
3.0
3v3oC-5ujuA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 ASP A 522
GLY A 525
THR A 526
SER A 521
None
1.04A 4ac9C-5ujuA:
3.2
4ac9C-5ujuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 ARG A 104
TRP A 111
GLY A 224
None
0.96A 4e7cA-5ujuA:
1.0
4e7cA-5ujuA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 8 PHE A 449
GLN A 139
GLY A 138
THR A 137
None
0.99A 4k87A-5ujuA:
4.4
4k87A-5ujuA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 ILE A 390
GLY A 340
ILE A 402
ALA A 405
ARG A 406
None
NA  A 601 (-3.8A)
None
None
None
0.97A 4kicB-5ujuA:
2.9
4kicB-5ujuA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 SER A 339
PHE A 208
ALA A 345
PHE A 449
VAL A 398
None
None
NA  A 601 ( 4.2A)
None
None
1.19A 4nc3A-5ujuA:
2.2
4nc3A-5ujuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 ILE A 452
GLN A 347
PRO A 346
ILE A 349
None
1.06A 4w5oA-5ujuA:
5.3
4w5oA-5ujuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 ILE A 452
GLN A 347
PRO A 346
ILE A 349
None
1.06A 4z4eA-5ujuA:
5.3
4z4eA-5ujuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 7 ILE A 452
GLN A 347
PRO A 346
ILE A 349
None
1.07A 4z4gA-5ujuA:
5.5
4z4gA-5ujuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 246
LEU A 250
ARG A 251
GLY A 113
HIS A   9
None
1.27A 5dx3A-5ujuA:
undetectable
5dx3A-5ujuA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.48A 5eeuA-5ujuA:
undetectable
5eeuB-5ujuA:
undetectable
5eeuA-5ujuA:
8.35
5eeuB-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eeuB-5ujuA:
undetectable
5eeuC-5ujuA:
undetectable
5eeuB-5ujuA:
8.35
5eeuC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeuC-5ujuA:
undetectable
5eeuD-5ujuA:
undetectable
5eeuC-5ujuA:
8.35
5eeuD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeuE-5ujuA:
undetectable
5eeuF-5ujuA:
undetectable
5eeuE-5ujuA:
8.35
5eeuF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeuG-5ujuA:
undetectable
5eeuH-5ujuA:
undetectable
5eeuG-5ujuA:
8.35
5eeuH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5eeuH-5ujuA:
undetectable
5eeuI-5ujuA:
undetectable
5eeuH-5ujuA:
8.35
5eeuI-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eeuA-5ujuA:
undetectable
5eeuK-5ujuA:
undetectable
5eeuA-5ujuA:
8.35
5eeuK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeuL-5ujuA:
undetectable
5eeuV-5ujuA:
undetectable
5eeuL-5ujuA:
8.35
5eeuV-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.41A 5eeuT-5ujuA:
undetectable
5eeuU-5ujuA:
undetectable
5eeuT-5ujuA:
8.35
5eeuU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eevB-5ujuA:
undetectable
5eevC-5ujuA:
undetectable
5eevB-5ujuA:
8.35
5eevC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eevC-5ujuA:
undetectable
5eevD-5ujuA:
undetectable
5eevC-5ujuA:
8.35
5eevD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eevE-5ujuA:
undetectable
5eevF-5ujuA:
undetectable
5eevE-5ujuA:
8.35
5eevF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eevG-5ujuA:
undetectable
5eevH-5ujuA:
undetectable
5eevG-5ujuA:
8.35
5eevH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5eevH-5ujuA:
undetectable
5eevI-5ujuA:
undetectable
5eevH-5ujuA:
8.35
5eevI-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eevA-5ujuA:
undetectable
5eevK-5ujuA:
undetectable
5eevA-5ujuA:
8.35
5eevK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5eevT-5ujuA:
undetectable
5eevU-5ujuA:
undetectable
5eevT-5ujuA:
8.35
5eevU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eewB-5ujuA:
undetectable
5eewC-5ujuA:
undetectable
5eewB-5ujuA:
8.35
5eewC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eewC-5ujuA:
undetectable
5eewD-5ujuA:
undetectable
5eewC-5ujuA:
8.35
5eewD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eewE-5ujuA:
undetectable
5eewF-5ujuA:
undetectable
5eewE-5ujuA:
8.35
5eewF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eewG-5ujuA:
undetectable
5eewH-5ujuA:
undetectable
5eewG-5ujuA:
8.35
5eewH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eewA-5ujuA:
undetectable
5eewK-5ujuA:
undetectable
5eewA-5ujuA:
8.35
5eewK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5eewT-5ujuA:
undetectable
5eewU-5ujuA:
undetectable
5eewT-5ujuA:
8.35
5eewU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eexB-5ujuA:
undetectable
5eexC-5ujuA:
undetectable
5eexB-5ujuA:
8.35
5eexC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eexC-5ujuA:
undetectable
5eexD-5ujuA:
undetectable
5eexC-5ujuA:
8.35
5eexD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eexE-5ujuA:
undetectable
5eexF-5ujuA:
undetectable
5eexE-5ujuA:
8.35
5eexF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eexG-5ujuA:
undetectable
5eexH-5ujuA:
undetectable
5eexG-5ujuA:
8.35
5eexH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eexA-5ujuA:
undetectable
5eexK-5ujuA:
undetectable
5eexA-5ujuA:
8.35
5eexK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eexL-5ujuA:
undetectable
5eexV-5ujuA:
undetectable
5eexL-5ujuA:
8.35
5eexV-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5eexT-5ujuA:
undetectable
5eexU-5ujuA:
undetectable
5eexT-5ujuA:
8.35
5eexU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eeyB-5ujuA:
undetectable
5eeyC-5ujuA:
undetectable
5eeyB-5ujuA:
8.35
5eeyC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eeyC-5ujuA:
undetectable
5eeyD-5ujuA:
undetectable
5eeyC-5ujuA:
8.35
5eeyD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eeyE-5ujuA:
undetectable
5eeyF-5ujuA:
undetectable
5eeyE-5ujuA:
8.35
5eeyF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeyG-5ujuA:
undetectable
5eeyH-5ujuA:
undetectable
5eeyG-5ujuA:
8.35
5eeyH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5eeyH-5ujuA:
undetectable
5eeyI-5ujuA:
undetectable
5eeyH-5ujuA:
8.35
5eeyI-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eeyA-5ujuA:
undetectable
5eeyK-5ujuA:
undetectable
5eeyA-5ujuA:
8.35
5eeyK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eeyL-5ujuA:
undetectable
5eeyV-5ujuA:
undetectable
5eeyL-5ujuA:
8.35
5eeyV-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5eeyT-5ujuA:
undetectable
5eeyU-5ujuA:
undetectable
5eeyT-5ujuA:
8.35
5eeyU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5eezB-5ujuA:
undetectable
5eezC-5ujuA:
undetectable
5eezB-5ujuA:
8.35
5eezC-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eezC-5ujuA:
undetectable
5eezD-5ujuA:
undetectable
5eezC-5ujuA:
8.35
5eezD-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5eezE-5ujuA:
undetectable
5eezF-5ujuA:
undetectable
5eezE-5ujuA:
8.35
5eezF-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eezG-5ujuA:
undetectable
5eezH-5ujuA:
undetectable
5eezG-5ujuA:
8.35
5eezH-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5eezH-5ujuA:
undetectable
5eezI-5ujuA:
undetectable
5eezH-5ujuA:
8.35
5eezI-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5eezJ-5ujuA:
undetectable
5eezK-5ujuA:
undetectable
5eezJ-5ujuA:
8.35
5eezK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5eezA-5ujuA:
undetectable
5eezK-5ujuA:
undetectable
5eezA-5ujuA:
8.35
5eezK-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 8 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5eezL-5ujuA:
undetectable
5eezV-5ujuA:
undetectable
5eezL-5ujuA:
8.35
5eezV-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5eezT-5ujuA:
undetectable
5eezU-5ujuA:
undetectable
5eezT-5ujuA:
8.35
5eezU-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5ef0B-5ujuA:
undetectable
5ef0C-5ujuA:
undetectable
5ef0B-5ujuA:
8.35
5ef0C-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef0C-5ujuA:
undetectable
5ef0D-5ujuA:
undetectable
5ef0C-5ujuA:
8.35
5ef0D-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef0E-5ujuA:
undetectable
5ef0F-5ujuA:
undetectable
5ef0E-5ujuA:
8.35
5ef0F-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef0G-5ujuA:
undetectable
5ef0H-5ujuA:
undetectable
5ef0G-5ujuA:
8.35
5ef0H-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5ef0H-5ujuA:
undetectable
5ef0I-5ujuA:
undetectable
5ef0H-5ujuA:
8.35
5ef0I-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.42A 5ef0J-5ujuA:
undetectable
5ef0K-5ujuA:
undetectable
5ef0J-5ujuA:
8.35
5ef0K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5ef0A-5ujuA:
undetectable
5ef0K-5ujuA:
undetectable
5ef0A-5ujuA:
8.35
5ef0K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef0L-5ujuA:
undetectable
5ef0V-5ujuA:
undetectable
5ef0L-5ujuA:
8.35
5ef0V-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5ef0T-5ujuA:
undetectable
5ef0U-5ujuA:
undetectable
5ef0T-5ujuA:
8.35
5ef0U-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5ef1B-5ujuA:
undetectable
5ef1C-5ujuA:
undetectable
5ef1B-5ujuA:
8.35
5ef1C-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef1C-5ujuA:
undetectable
5ef1D-5ujuA:
undetectable
5ef1C-5ujuA:
8.35
5ef1D-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef1E-5ujuA:
undetectable
5ef1F-5ujuA:
undetectable
5ef1E-5ujuA:
8.35
5ef1F-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef1G-5ujuA:
undetectable
5ef1H-5ujuA:
undetectable
5ef1G-5ujuA:
8.35
5ef1H-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5ef1H-5ujuA:
undetectable
5ef1I-5ujuA:
undetectable
5ef1H-5ujuA:
8.35
5ef1I-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.42A 5ef1J-5ujuA:
undetectable
5ef1K-5ujuA:
undetectable
5ef1J-5ujuA:
8.35
5ef1K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.44A 5ef1A-5ujuA:
undetectable
5ef1K-5ujuA:
undetectable
5ef1A-5ujuA:
8.35
5ef1K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 8 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef1L-5ujuA:
undetectable
5ef1V-5ujuA:
undetectable
5ef1L-5ujuA:
8.35
5ef1V-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5ef1T-5ujuA:
undetectable
5ef1U-5ujuA:
undetectable
5ef1T-5ujuA:
8.35
5ef1U-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5ef2B-5ujuA:
undetectable
5ef2C-5ujuA:
undetectable
5ef2B-5ujuA:
8.35
5ef2C-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef2C-5ujuA:
undetectable
5ef2D-5ujuA:
undetectable
5ef2C-5ujuA:
8.35
5ef2D-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef2E-5ujuA:
undetectable
5ef2F-5ujuA:
undetectable
5ef2E-5ujuA:
8.35
5ef2F-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef2G-5ujuA:
undetectable
5ef2H-5ujuA:
undetectable
5ef2G-5ujuA:
8.35
5ef2H-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5ef2H-5ujuA:
undetectable
5ef2I-5ujuA:
undetectable
5ef2H-5ujuA:
8.35
5ef2I-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.42A 5ef2J-5ujuA:
undetectable
5ef2K-5ujuA:
undetectable
5ef2J-5ujuA:
8.35
5ef2K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.45A 5ef2A-5ujuA:
undetectable
5ef2K-5ujuA:
undetectable
5ef2A-5ujuA:
8.35
5ef2K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 8 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef2L-5ujuA:
undetectable
5ef2V-5ujuA:
undetectable
5ef2L-5ujuA:
8.35
5ef2V-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5ef2T-5ujuA:
undetectable
5ef2U-5ujuA:
undetectable
5ef2T-5ujuA:
8.35
5ef2U-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.41A 5ef3B-5ujuA:
undetectable
5ef3C-5ujuA:
undetectable
5ef3B-5ujuA:
8.35
5ef3C-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.44A 5ef3C-5ujuA:
undetectable
5ef3D-5ujuA:
undetectable
5ef3C-5ujuA:
8.35
5ef3D-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5ef3E-5ujuA:
undetectable
5ef3F-5ujuA:
undetectable
5ef3E-5ujuA:
8.35
5ef3F-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.45A 5ef3G-5ujuA:
undetectable
5ef3H-5ujuA:
undetectable
5ef3G-5ujuA:
8.35
5ef3H-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.43A 5ef3H-5ujuA:
undetectable
5ef3I-5ujuA:
undetectable
5ef3H-5ujuA:
8.35
5ef3I-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 THR A 210
SER A 132
ALA A 144
THR A 136
THR A 137
None
1.42A 5ef3J-5ujuA:
undetectable
5ef3K-5ujuA:
undetectable
5ef3J-5ujuA:
8.35
5ef3K-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 ALA A 144
THR A 136
THR A 137
THR A 210
SER A 132
None
1.42A 5ef3T-5ujuA:
undetectable
5ef3U-5ujuA:
undetectable
5ef3T-5ujuA:
8.35
5ef3U-5ujuA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 VAL A 438
GLU A 474
GLU A 470
None
0.91A 5jsdB-5ujuA:
undetectable
5jsdC-5ujuA:
undetectable
5jsdB-5ujuA:
22.03
5jsdC-5ujuA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
6 / 12 THR A 321
THR A 358
ILE A 349
ALA A 328
ALA A 371
ILE A 372
None
1.31A 5kb6A-5ujuA:
undetectable
5kb6A-5ujuA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 9 ASN A 314
GLY A 312
ALA A 477
GLY A 525
VAL A 514
None
1.00A 5kr0B-5ujuA:
undetectable
5kr0B-5ujuA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 LEU A 157
ALA A 161
LEU A  13
THR A   2
ALA A 222
None
1.28A 5xiwD-5ujuA:
undetectable
5xiwD-5ujuA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 ILE A 316
ASN A 515
CYH A 343
None
0.83A 6bp4A-5ujuA:
undetectable
6bp4A-5ujuA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 12 SER A 339
PHE A 208
ALA A 345
PHE A 449
VAL A 398
None
None
NA  A 601 ( 4.2A)
None
None
1.15A 6drxA-5ujuA:
undetectable
6drxA-5ujuA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 5 GLY A 397
ASN A 395
ASP A 396
ARG A 427
None
1.27A 6dwdB-5ujuA:
undetectable
6dwdD-5ujuA:
undetectable
6dwdB-5ujuA:
24.56
6dwdD-5ujuA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 5 ARG A 427
GLY A 397
ASN A 395
ASP A 396
None
1.27A 6dwjB-5ujuA:
undetectable
6dwjD-5ujuA:
1.2
6dwjB-5ujuA:
24.56
6dwjD-5ujuA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
4 / 4 LEU A 276
ASP A  90
PRO A  89
ARG A 279
None
1.43A 6fgdA-5ujuA:
4.6
6fgdA-5ujuA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
5 / 10 GLY A 501
ALA A 477
LEU A 478
GLY A 525
LEU A 389
None
1.17A 6hqbA-5ujuA:
2.6
6hqbJ-5ujuA:
undetectable
6hqbA-5ujuA:
9.57
6hqbJ-5ujuA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans)
3 / 3 THR A 526
GLU A 298
ASN A 529
None
0.71A 6nj9K-5ujuA:
4.7
6nj9K-5ujuA:
21.10