SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ujz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G  10
THR G 104
PRO G   8
 None
 0.80A 1a7yB-5ujzG:
undetectable		 1a7yB-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G  10
THR G 104
PRO G   8
 None
 0.85A 1i3wE-5ujzG:
undetectable		 1i3wE-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.85A 1i3wG-5ujzG:
undetectable		 1i3wG-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G  10
THR G 104
PRO G   8
 None
 0.80A 1qfiB-5ujzG:
undetectable		 1qfiB-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.73A 1unjF-5ujzG:
undetectable		 1unjF-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G  10
THR G 104
PRO G   8
 None
 0.85A 1unjF-5ujzG:
undetectable		 1unjF-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.83A 1unjL-5ujzG:
undetectable		 1unjL-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.86A 1unjX-5ujzG:
undetectable		 1unjX-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.83A 1unmE-5ujzG:
undetectable		 1unmE-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 PRO A  69
GLY A  67
THR A  93
GLY A  63
 None
 0.79A 1usqA-5ujzA:
undetectable		 1usqA-5ujzA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.97A 1wmqA-5ujzA:
undetectable		 1wmqA-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.96A 1wmqB-5ujzA:
undetectable		 1wmqB-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.97A 1wpuA-5ujzA:
undetectable		 1wpuA-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.97A 1wpuB-5ujzA:
undetectable		 1wpuB-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.93A 1wrqA-5ujzA:
undetectable		 1wrqA-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 6 ARG A 192
ILE A 188
GLY A 189
ALA A 193
 None
 0.93A 1wrqB-5ujzA:
undetectable		 1wrqB-5ujzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 5 TRP A  80
PRO A  53
LEU A  48
GLY A 304
 None
 1.38A 1ya4C-5ujzA:
undetectable		 1ya4C-5ujzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		3 / 3 TRP A 180
ARG A 211
PHE A 213
 None
 1.48A 1zeaH-5ujzA:
undetectable
1zeaL-5ujzA:
undetectable		 1zeaH-5ujzA:
19.70
1zeaL-5ujzA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		5 / 12 LEU A  66
LEU A 151
LEU A 152
LEU A 251
THR A  93
 None
 1.23A 1zucB-5ujzA:
undetectable		 1zucB-5ujzA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5ujz SCFV
(Homo
sapiens) 		5 / 10 GLN G   6
LEU G  21
SER G  12
LEU G  11
ASN G 105
 None
 1.36A 2ceoB-5ujzG:
undetectable		 2ceoB-5ujzG:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		4 / 7 PRO A  69
GLY A  67
THR A  93
GLY A  63
 None
 0.84A 2jklA-5ujzA:
undetectable		 2jklA-5ujzA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		5 / 11 GLY B 512
GLY B 513
ASN A 323
GLU B 511
ILE B 510
 None
 1.47A 3owxA-5ujzB:
undetectable
3owxB-5ujzB:
undetectable		 3owxA-5ujzB:
23.48
3owxB-5ujzB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ujz SCFV
(Homo
sapiens) 		4 / 5 ILE G  98
TRP G 172
HIS G 160
GLY G 175
 None
 1.23A 4e7cC-5ujzG:
undetectable		 4e7cC-5ujzG:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5ujz SCFV
(Homo
sapiens) 		5 / 10 ILE G 156
GLY G 232
GLY G 231
THR G 153
PHE G 152
 None
 0.89A 4fakA-5ujzG:
undetectable		 4fakA-5ujzG:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 104
PRO G   8
THR G  10
 None
 0.82A 4hivD-5ujzG:
undetectable		 4hivD-5ujzG:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		4 / 6 ASN A  15
ASP A  18
GLY A 320
THR B 515
 NAG  A 408 (-1.8A)
None
None
None
 0.98A 4l1aB-5ujzA:
undetectable		 4l1aB-5ujzA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		5 / 10 VAL B 615
TYR A  11
GLY B 636
GLY B 523
ASP B 612
 None
 1.30A 4mmcA-5ujzB:
1.8		 4mmcA-5ujzB:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		4 / 7 TYR B 522
ILE A   9
GLY B 513
LEU A 321
 None
 0.84A 4ze3A-5ujzB:
undetectable		 4ze3A-5ujzB:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		4 / 4 VAL B 555
ILE B 548
ASN B 604
VAL A  34
 None
 0.93A 5ajqA-5ujzB:
undetectable		 5ajqA-5ujzB:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		4 / 6 ARG A 311
GLY B 587
ASP B 590
ASP B 585
 None
 1.24A 5hp1A-5ujzA:
undetectable		 5hp1A-5ujzA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5ujz SCFV
(Homo
sapiens) 		4 / 5 PRO G  45
HIS G 160
LEU G  34
TYR G 236
 None
 1.40A 5igjA-5ujzG:
undetectable		 5igjA-5ujzG:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ujz SCFV
(Homo
sapiens) 		4 / 4 GLU G  17
PRO G  15
ILE G 108
LEU G  13
 None
 1.26A 5m45A-5ujzG:
undetectable		 5m45A-5ujzG:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ujz SCFV
(Homo
sapiens) 		4 / 4 GLU G  17
PRO G  15
ILE G 108
LEU G  13
 None
 1.35A 5m45D-5ujzG:
undetectable		 5m45D-5ujzG:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ujz SCFV
(Homo
sapiens) 		4 / 4 GLU G  17
PRO G  15
ILE G 108
LEU G  13
 None
 1.26A 5m45G-5ujzG:
undetectable		 5m45G-5ujzG:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ujz SCFV
(Homo
sapiens) 		3 / 3 THR G 177
MET G 159
HIS G 160
 None
 0.97A 5uunA-5ujzG:
undetectable		 5uunA-5ujzG:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2
(Influenza
A
virus) 		4 / 7 ALA B 536
GLY B 523
TYR B 522
TYR A  11
 None
 1.10A 5uxdA-5ujzB:
undetectable		 5uxdA-5ujzB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ujz HEMAGGLUTININ HA1
(Influenza
A
virus) 		3 / 3 ARG A 262
PHE A 258
LEU A 236
 None
 0.90A 5x1bC-5ujzA:
undetectable		 5x1bC-5ujzA:
21.96