SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ukb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		4 / 7 ALA d  61
PHE d  37
ARG d  33
ASN d  59
 None
 1.21A 1t9wA-5ukbd:
undetectable		 1t9wA-5ukbd:
9.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		6 / 12 ALA d  24
ARG d  30
ARG d  72
ASN d  77
VAL d  79
ALA d  98
 None
 1.05A 3qxtA-5ukbd:
22.4		 3qxtA-5ukbd:
72.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		6 / 12 LEU d   4
ALA d  24
ARG d  72
VAL d  79
ALA d  98
TYR d 113
 None
 0.66A 3qxtB-5ukbd:
22.6		 3qxtB-5ukbd:
72.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		6 / 12 LEU d   4
ARG d  30
ARG d  72
VAL d  79
ALA d  98
TYR d 113
 None
 0.78A 3qxtB-5ukbd:
22.6		 3qxtB-5ukbd:
72.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		6 / 12 VAL d   2
LEU d   4
ALA d  24
VAL d  79
ALA d  98
TYR d 113
 None
 0.89A 3qxtB-5ukbd:
22.6		 3qxtB-5ukbd:
72.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		5 / 12 ALA d  24
ARG d  72
VAL d  79
ALA d  98
TYR d 113
 None
 0.77A 3qxvB-5ukbd:
22.4		 3qxvB-5ukbd:
70.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		5 / 12 ALA d  24
ARG d  72
VAL d  79
ALA d  98
TYR d 113
 None
 0.74A 3qxvD-5ukbd:
22.3		 3qxvD-5ukbd:
70.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		5 / 12 ALA d  24
ARG d  72
VAL d  79
ALA d  98
TYR d 113
 None
 0.75A 3qxvE-5ukbd:
19.3		 3qxvE-5ukbd:
70.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5ukb ANTI-VESICULAR
STOMATITIS VIRUS N
VHH
(Vicugna
pacos) 		4 / 8 PRO d 105
PHE d  37
PHE d  99
TRP d 114
 None
 1.25A 5amkA-5ukbd:
undetectable		 5amkA-5ukbd:
20.83