SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ukh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 LEU A 341
ILE A 407
THR A 403
TRP A 287
None
1.21A 1kglA-5ukhA:
undetectable
1kglA-5ukhA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 LEU A 249
LEU A 247
MET A 479
TYR A 475
HIS A 231
None
1.33A 1kt4A-5ukhA:
undetectable
1kt4A-5ukhA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 LEU A 249
LEU A 247
MET A 479
TYR A 475
HIS A 231
None
1.32A 1kt5A-5ukhA:
undetectable
1kt5A-5ukhA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 11 LEU A 249
LEU A 247
MET A 479
TYR A 475
HIS A 231
None
1.37A 1kt7A-5ukhA:
undetectable
1kt7A-5ukhA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 4 HIS A 404
ASP A 537
SER A 539
ASP A 439
CA  A 601 ( 4.8A)
None
None
None
1.42A 1n2xA-5ukhA:
undetectable
1n2xA-5ukhA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
3 / 3 ASP A 512
TYR A 511
GLU A 504
None
0.85A 1vm1A-5ukhA:
undetectable
1vm1A-5ukhA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
3 / 3 PHE A 274
ARG A 296
ASN A 414
None
0.87A 1xzxX-5ukhA:
undetectable
1xzxX-5ukhA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 ALA A 243
TYR A 236
TYR A 483
PHE A 228
None
1.15A 2ajvH-5ukhA:
undetectable
2ajvL-5ukhA:
undetectable
2ajvH-5ukhA:
21.51
2ajvL-5ukhA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 GLN A 336
ALA A 332
LEU A 272
LEU A 319
SER A 317
None
1.32A 2nv4A-5ukhA:
undetectable
2nv4A-5ukhA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 GLN A 336
ALA A 332
LEU A 272
LEU A 319
SER A 317
None
1.18A 2nv4B-5ukhA:
undetectable
2nv4B-5ukhA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 LEU A 253
ASP A 270
TYR A 271
HIS A 404
None
None
None
CA  A 601 ( 4.8A)
1.00A 2y69C-5ukhA:
undetectable
2y69N-5ukhA:
undetectable
2y69P-5ukhA:
undetectable
2y69C-5ukhA:
19.51
2y69N-5ukhA:
20.30
2y69P-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 SER A 340
PHE A 238
ILE A 246
PHE A 322
LEU A 373
None
1.45A 3aocC-5ukhA:
undetectable
3aocC-5ukhA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 5 SER A 281
ASP A 454
ASP A 537
ILE A 451
None
CA  A 601 (-3.1A)
None
None
1.20A 3uj7B-5ukhA:
undetectable
3uj7B-5ukhA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 11 GLY A 435
ASP A 439
ASP A 537
VAL A 538
LEU A 514
None
1.14A 3v8vB-5ukhA:
undetectable
3v8vB-5ukhA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 9 ILE A 407
ILE A 276
PHE A 298
PHE A 257
TYR A 297
None
1.49A 4afgA-5ukhA:
undetectable
4afgE-5ukhA:
undetectable
4afgA-5ukhA:
21.37
4afgE-5ukhA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 GLN A 336
LEU A 335
GLY A 278
ASN A 283
ALA A 410
None
1.30A 4pclB-5ukhA:
undetectable
4pclB-5ukhA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 5 THR A 441
THR A 440
THR A 408
HIS A 412
None
1.32A 4pgfB-5ukhA:
undetectable
4pgfB-5ukhA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
1.00A 5b1bA-5ukhA:
undetectable
5b1bC-5ukhA:
undetectable
5b1bP-5ukhA:
undetectable
5b1bA-5ukhA:
20.30
5b1bC-5ukhA:
19.51
5b1bP-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 ASP A 454
ASP A 455
TYR A 282
ASP A 401
CA  A 601 (-3.1A)
CA  A 601 (-2.3A)
None
CA  A 601 (-3.4A)
1.04A 5cfsA-5ukhA:
1.1
5cfsA-5ukhA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 6 ASP A 454
GLY A 452
ASP A 537
ASP A 455
CA  A 601 (-3.1A)
None
None
CA  A 601 (-2.3A)
1.02A 5hp1A-5ukhA:
undetectable
5hp1A-5ukhA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.39A 5jhnB-5ukhA:
undetectable
5jhnB-5ukhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIN_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.40A 5jinA-5ukhA:
undetectable
5jinA-5ukhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.39A 5jinB-5ukhA:
undetectable
5jinB-5ukhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.39A 5jj0A-5ukhA:
undetectable
5jj0A-5ukhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.42A 5jj0B-5ukhA:
undetectable
5jj0B-5ukhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 6 LEU A 341
ILE A 407
THR A 403
TRP A 287
None
1.44A 5ljeA-5ukhA:
undetectable
5ljeA-5ukhA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.40A 5t0kA-5ukhA:
undetectable
5t0kA-5ukhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.41A 5t0kB-5ukhA:
undetectable
5t0kB-5ukhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.38A 5t0mA-5ukhA:
undetectable
5t0mA-5ukhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.44A 5t0mB-5ukhA:
undetectable
5t0mB-5ukhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.36A 5ttfB-5ukhA:
undetectable
5ttfB-5ukhA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.32A 5v9iA-5ukhA:
undetectable
5v9iA-5ukhA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 12 MET A 479
SER A 406
TYR A 236
PHE A 402
GLN A 476
None
1.36A 5vscB-5ukhA:
undetectable
5vscB-5ukhA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
1.01A 5w97A-5ukhA:
undetectable
5w97C-5ukhA:
undetectable
5w97c-5ukhA:
undetectable
5w97A-5ukhA:
20.30
5w97C-5ukhA:
19.51
5w97c-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 LEU A 253
ASP A 270
TYR A 271
HIS A 404
None
None
None
CA  A 601 ( 4.8A)
1.01A 5w97C-5ukhA:
undetectable
5w97a-5ukhA:
undetectable
5w97c-5ukhA:
undetectable
5w97C-5ukhA:
19.51
5w97a-5ukhA:
20.30
5w97c-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 LEU A 253
ASP A 270
TYR A 271
HIS A 404
None
None
None
CA  A 601 ( 4.8A)
0.95A 5wauC-5ukhA:
undetectable
5waua-5ukhA:
undetectable
5wauc-5ukhA:
undetectable
5wauC-5ukhA:
19.51
5waua-5ukhA:
20.30
5wauc-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
0.90A 5x19A-5ukhA:
undetectable
5x19C-5ukhA:
undetectable
5x19P-5ukhA:
undetectable
5x19A-5ukhA:
20.30
5x19C-5ukhA:
19.51
5x19P-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
0.92A 5x1bA-5ukhA:
undetectable
5x1bC-5ukhA:
undetectable
5x1bP-5ukhA:
undetectable
5x1bA-5ukhA:
20.30
5x1bC-5ukhA:
19.51
5x1bP-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
0.92A 5x1fA-5ukhA:
undetectable
5x1fC-5ukhA:
undetectable
5x1fP-5ukhA:
undetectable
5x1fA-5ukhA:
20.30
5x1fC-5ukhA:
19.51
5x1fP-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
3 / 3 SER A 539
LYS A 540
SER A 543
None
0.71A 6az3P-5ukhA:
undetectable
6az3P-5ukhA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
5 / 9 LEU A 272
SER A 279
GLY A 278
ILE A 277
ILE A 321
None
1.30A 6ebpA-5ukhA:
undetectable
6ebpA-5ukhA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 HIS A 404
THR A 408
ARG A 493
ASP A 461
CA  A 601 ( 4.8A)
None
None
None
1.34A 6mn4E-5ukhA:
undetectable
6mn4E-5ukhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 8 LEU A 253
ASP A 270
TYR A 271
HIS A 404
None
None
None
CA  A 601 ( 4.8A)
0.94A 6nknC-5ukhA:
undetectable
6nknN-5ukhA:
undetectable
6nknP-5ukhA:
undetectable
6nknC-5ukhA:
19.51
6nknN-5ukhA:
20.30
6nknP-5ukhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ukh UNCHARACTERIZED
PROTEIN

(Streptococcus
intermedius)
4 / 7 ASP A 270
TYR A 271
HIS A 404
LEU A 253
None
None
CA  A 601 ( 4.8A)
None
0.91A 6nmfA-5ukhA:
undetectable
6nmfC-5ukhA:
undetectable
6nmfP-5ukhA:
undetectable
6nmfA-5ukhA:
20.30
6nmfC-5ukhA:
19.51
6nmfP-5ukhA:
19.51