SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 1c9sA-5ukiA:
undetectable
1c9sK-5ukiA:
undetectable		 1c9sA-5ukiA:
undetectable
1c9sK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 1c9sC-5ukiA:
undetectable
1c9sD-5ukiA:
undetectable		 1c9sC-5ukiA:
undetectable
1c9sD-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 1c9sD-5ukiA:
undetectable
1c9sE-5ukiA:
undetectable		 1c9sD-5ukiA:
undetectable
1c9sE-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 1c9sE-5ukiA:
undetectable
1c9sF-5ukiA:
undetectable		 1c9sE-5ukiA:
undetectable
1c9sF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 1c9sF-5ukiA:
undetectable
1c9sG-5ukiA:
undetectable		 1c9sF-5ukiA:
undetectable
1c9sG-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 1c9sH-5ukiA:
undetectable
1c9sI-5ukiA:
undetectable		 1c9sH-5ukiA:
undetectable
1c9sI-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 1c9sJ-5ukiA:
undetectable
1c9sK-5ukiA:
undetectable		 1c9sJ-5ukiA:
undetectable
1c9sK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.47A 1c9sO-5ukiA:
undetectable
1c9sP-5ukiA:
undetectable		 1c9sO-5ukiA:
undetectable
1c9sP-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 1gtfA-5ukiA:
undetectable
1gtfK-5ukiA:
undetectable		 1gtfA-5ukiA:
undetectable
1gtfK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 1gtfB-5ukiA:
undetectable
1gtfC-5ukiA:
undetectable		 1gtfB-5ukiA:
undetectable
1gtfC-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 1gtfE-5ukiA:
undetectable
1gtfF-5ukiA:
undetectable		 1gtfE-5ukiA:
undetectable
1gtfF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 1gtfI-5ukiA:
undetectable
1gtfJ-5ukiA:
undetectable		 1gtfI-5ukiA:
undetectable
1gtfJ-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.46A 1gtfP-5ukiA:
undetectable
1gtfQ-5ukiA:
undetectable		 1gtfP-5ukiA:
undetectable
1gtfQ-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 ASP A  45
HIS A  91
HIS A  16
 MN  A 401 ( 2.4A)
None
ZN  A 400 (-3.3A)
 0.58A 1oe1A-5ukiA:
undetectable		 1oe1A-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 ASP A  45
HIS A  91
HIS A  16
 MN  A 401 ( 2.4A)
None
ZN  A 400 (-3.3A)
 0.57A 1oe3A-5ukiA:
undetectable		 1oe3A-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 1utdA-5ukiA:
undetectable
1utdB-5ukiA:
undetectable		 1utdA-5ukiA:
undetectable
1utdB-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 1utdC-5ukiA:
undetectable
1utdD-5ukiA:
undetectable		 1utdC-5ukiA:
undetectable
1utdD-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 1utdD-5ukiA:
undetectable
1utdE-5ukiA:
undetectable		 1utdD-5ukiA:
undetectable
1utdE-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 1utdA-5ukiA:
undetectable
1utdK-5ukiA:
undetectable		 1utdA-5ukiA:
undetectable
1utdK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 1utdN-5ukiA:
undetectable
1utdO-5ukiA:
undetectable		 1utdN-5ukiA:
undetectable
1utdO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		4 / 8 SER A 177
VAL A 129
LEU A 218
PRO A 183
 None
 1.01A 2ddwA-5ukiA:
undetectable		 2ddwA-5ukiA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 ASP A  45
HIS A  91
HIS A  16
 MN  A 401 ( 2.4A)
None
ZN  A 400 (-3.3A)
 0.60A 2xxgA-5ukiA:
undetectable		 2xxgA-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 ASP A  45
HIS A  91
HIS A  16
 MN  A 401 ( 2.4A)
None
ZN  A 400 (-3.3A)
 0.61A 2xxgC-5ukiA:
undetectable		 2xxgC-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		4 / 7 ILE A 121
SER A 117
TYR A 271
TYR A 111
 None
 1.23A 2xz5D-5ukiA:
undetectable
2xz5E-5ukiA:
undetectable		 2xz5D-5ukiA:
undetectable
2xz5E-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 TYR A  82
CYH A  42
VAL A  12
GLY A  13
LEU A 247
 None
 1.01A 3ijdB-5ukiA:
undetectable		 3ijdB-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		4 / 5 ASP A 137
ASP A 181
PHE A 155
GLY A 131
 None
 0.84A 4xp6A-5ukiA:
undetectable		 4xp6A-5ukiA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5eeuA-5ukiA:
undetectable
5eeuB-5ukiA:
undetectable		 5eeuA-5ukiA:
undetectable
5eeuB-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5eeuE-5ukiA:
undetectable
5eeuF-5ukiA:
undetectable		 5eeuE-5ukiA:
undetectable
5eeuF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.47A 5eeuG-5ukiA:
undetectable
5eeuH-5ukiA:
undetectable		 5eeuG-5ukiA:
undetectable
5eeuH-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5eeuA-5ukiA:
undetectable
5eeuK-5ukiA:
undetectable		 5eeuA-5ukiA:
undetectable
5eeuK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.45A 5eeuN-5ukiA:
undetectable
5eeuO-5ukiA:
undetectable		 5eeuN-5ukiA:
undetectable
5eeuO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eevE-5ukiA:
undetectable
5eevF-5ukiA:
undetectable		 5eevE-5ukiA:
undetectable
5eevF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5eevH-5ukiA:
undetectable
5eevI-5ukiA:
undetectable		 5eevH-5ukiA:
undetectable
5eevI-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5eevA-5ukiA:
undetectable
5eevK-5ukiA:
undetectable		 5eevA-5ukiA:
undetectable
5eevK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.45A 5eevN-5ukiA:
undetectable
5eevO-5ukiA:
undetectable		 5eevN-5ukiA:
undetectable
5eevO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5eewB-5ukiA:
undetectable
5eewC-5ukiA:
undetectable		 5eewB-5ukiA:
undetectable
5eewC-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eewE-5ukiA:
undetectable
5eewF-5ukiA:
undetectable		 5eewE-5ukiA:
undetectable
5eewF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5eewA-5ukiA:
undetectable
5eewK-5ukiA:
undetectable		 5eewA-5ukiA:
undetectable
5eewK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.45A 5eewN-5ukiA:
undetectable
5eewO-5ukiA:
undetectable		 5eewN-5ukiA:
undetectable
5eewO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5eexB-5ukiA:
undetectable
5eexC-5ukiA:
undetectable		 5eexB-5ukiA:
undetectable
5eexC-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eexE-5ukiA:
undetectable
5eexF-5ukiA:
undetectable		 5eexE-5ukiA:
undetectable
5eexF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.45A 5eexN-5ukiA:
undetectable
5eexO-5ukiA:
undetectable		 5eexN-5ukiA:
undetectable
5eexO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5eexQ-5ukiA:
undetectable
5eexR-5ukiA:
undetectable		 5eexQ-5ukiA:
undetectable
5eexR-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eeyE-5ukiA:
undetectable
5eeyF-5ukiA:
undetectable		 5eeyE-5ukiA:
undetectable
5eeyF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eeyH-5ukiA:
undetectable
5eeyI-5ukiA:
undetectable		 5eeyH-5ukiA:
undetectable
5eeyI-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5eeyA-5ukiA:
undetectable
5eeyK-5ukiA:
undetectable		 5eeyA-5ukiA:
undetectable
5eeyK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5eeyN-5ukiA:
undetectable
5eeyO-5ukiA:
undetectable		 5eeyN-5ukiA:
undetectable
5eeyO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5eeyQ-5ukiA:
undetectable
5eeyR-5ukiA:
undetectable		 5eeyQ-5ukiA:
undetectable
5eeyR-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5eezB-5ukiA:
undetectable
5eezC-5ukiA:
undetectable		 5eezB-5ukiA:
undetectable
5eezC-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eezE-5ukiA:
undetectable
5eezF-5ukiA:
undetectable		 5eezE-5ukiA:
undetectable
5eezF-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.47A 5eezG-5ukiA:
undetectable
5eezH-5ukiA:
undetectable		 5eezG-5ukiA:
undetectable
5eezH-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5eezH-5ukiA:
undetectable
5eezI-5ukiA:
undetectable		 5eezH-5ukiA:
undetectable
5eezI-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5eezJ-5ukiA:
undetectable
5eezK-5ukiA:
undetectable		 5eezJ-5ukiA:
undetectable
5eezK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5eezA-5ukiA:
undetectable
5eezK-5ukiA:
undetectable		 5eezA-5ukiA:
undetectable
5eezK-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5eezN-5ukiA:
undetectable
5eezO-5ukiA:
undetectable		 5eezN-5ukiA:
undetectable
5eezO-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5eezQ-5ukiA:
undetectable
5eezR-5ukiA:
undetectable		 5eezQ-5ukiA:
undetectable
5eezR-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.50A 5ef0B-5ukiA:
undetectable
5ef0C-5ukiA:
undetectable		 5ef0B-5ukiA:
undetectable
5ef0C-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef0E-5ukiA:
undetectable
5ef0F-5ukiA:
undetectable		 5ef0E-5ukiA:
undetectable
5ef0F-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.47A 5ef0G-5ukiA:
undetectable
5ef0H-5ukiA:
undetectable		 5ef0G-5ukiA:
undetectable
5ef0H-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef0H-5ukiA:
undetectable
5ef0I-5ukiA:
undetectable		 5ef0H-5ukiA:
undetectable
5ef0I-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5ef0J-5ukiA:
undetectable
5ef0K-5ukiA:
undetectable		 5ef0J-5ukiA:
undetectable
5ef0K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5ef0N-5ukiA:
undetectable
5ef0O-5ukiA:
undetectable		 5ef0N-5ukiA:
undetectable
5ef0O-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef0Q-5ukiA:
undetectable
5ef0R-5ukiA:
undetectable		 5ef0Q-5ukiA:
undetectable
5ef0R-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef0T-5ukiA:
undetectable
5ef0U-5ukiA:
undetectable		 5ef0T-5ukiA:
undetectable
5ef0U-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef1E-5ukiA:
undetectable
5ef1F-5ukiA:
undetectable		 5ef1E-5ukiA:
undetectable
5ef1F-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 5ef1G-5ukiA:
undetectable
5ef1H-5ukiA:
undetectable		 5ef1G-5ukiA:
undetectable
5ef1H-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef1H-5ukiA:
undetectable
5ef1I-5ukiA:
undetectable		 5ef1H-5ukiA:
undetectable
5ef1I-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5ef1J-5ukiA:
undetectable
5ef1K-5ukiA:
undetectable		 5ef1J-5ukiA:
undetectable
5ef1K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5ef1A-5ukiA:
undetectable
5ef1K-5ukiA:
undetectable		 5ef1A-5ukiA:
undetectable
5ef1K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5ef1N-5ukiA:
undetectable
5ef1O-5ukiA:
undetectable		 5ef1N-5ukiA:
undetectable
5ef1O-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef1Q-5ukiA:
undetectable
5ef1R-5ukiA:
undetectable		 5ef1Q-5ukiA:
undetectable
5ef1R-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef2E-5ukiA:
undetectable
5ef2F-5ukiA:
undetectable		 5ef2E-5ukiA:
undetectable
5ef2F-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 5ef2G-5ukiA:
undetectable
5ef2H-5ukiA:
undetectable		 5ef2G-5ukiA:
undetectable
5ef2H-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef2H-5ukiA:
undetectable
5ef2I-5ukiA:
undetectable		 5ef2H-5ukiA:
undetectable
5ef2I-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5ef2J-5ukiA:
undetectable
5ef2K-5ukiA:
undetectable		 5ef2J-5ukiA:
undetectable
5ef2K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.49A 5ef2A-5ukiA:
undetectable
5ef2K-5ukiA:
undetectable		 5ef2A-5ukiA:
undetectable
5ef2K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5ef2N-5ukiA:
undetectable
5ef2O-5ukiA:
undetectable		 5ef2N-5ukiA:
undetectable
5ef2O-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef2Q-5ukiA:
undetectable
5ef2R-5ukiA:
undetectable		 5ef2Q-5ukiA:
undetectable
5ef2R-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef3E-5ukiA:
undetectable
5ef3F-5ukiA:
undetectable		 5ef3E-5ukiA:
undetectable
5ef3F-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.46A 5ef3G-5ukiA:
undetectable
5ef3H-5ukiA:
undetectable		 5ef3G-5ukiA:
undetectable
5ef3H-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.49A 5ef3H-5ukiA:
undetectable
5ef3I-5ukiA:
undetectable		 5ef3H-5ukiA:
undetectable
5ef3I-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 SER A 211
GLY A  89
HIS A 230
THR A 157
ILE A  87
 None
None
MN  A 401 (-3.4A)
None
None
 1.48A 5ef3J-5ukiA:
undetectable
5ef3K-5ukiA:
undetectable		 5ef3J-5ukiA:
undetectable
5ef3K-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.44A 5ef3N-5ukiA:
undetectable
5ef3O-5ukiA:
undetectable		 5ef3N-5ukiA:
undetectable
5ef3O-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef3Q-5ukiA:
undetectable
5ef3R-5ukiA:
undetectable		 5ef3Q-5ukiA:
undetectable
5ef3R-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A  89
HIS A 230
THR A 157
ILE A  87
SER A 211
 None
MN  A 401 (-3.4A)
None
None
None
 1.48A 5ef3T-5ukiA:
undetectable
5ef3U-5ukiA:
undetectable		 5ef3T-5ukiA:
undetectable
5ef3U-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A 210
GLY A 185
LEU A 209
LEU A 195
TYR A 235
 None
 1.14A 5hwkA-5ukiA:
undetectable		 5hwkA-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A 210
GLY A 185
LEU A 209
LEU A 195
TYR A 235
 None
 1.14A 5hwkB-5ukiA:
undetectable		 5hwkB-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		4 / 5 ILE A 322
LYS A 313
ILE A 315
VAL A 276
 None
 1.01A 5jmnA-5ukiA:
undetectable		 5jmnA-5ukiA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		4 / 4 ASP A  45
HIS A 180
HIS A 230
HIS A  91
 MN  A 401 ( 2.4A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
None
 1.48A 5ncdD-5ukiA:
undetectable		 5ncdD-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		6 / 10 LEU A 178
ILE A  87
GLY A  44
GLY A  13
VAL A  40
LEU A  85
 None
 1.30A 5o96C-5ukiA:
undetectable
5o96D-5ukiA:
undetectable		 5o96C-5ukiA:
undetectable
5o96D-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 ILE A 176
ILE A 174
LEU A 221
HIS A 236
ILE A 245
 None
 1.45A 5vkqA-5ukiA:
undetectable
5vkqD-5ukiA:
undetectable		 5vkqA-5ukiA:
undetectable
5vkqD-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 HIS A 236
ILE A 245
ILE A 176
ILE A 174
LEU A 221
 None
 1.42A 5vkqA-5ukiA:
undetectable
5vkqB-5ukiA:
undetectable		 5vkqA-5ukiA:
undetectable
5vkqB-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		5 / 10 HIS A 236
ILE A 245
ILE A 176
ILE A 174
LEU A 221
 None
 1.42A 5vkqC-5ukiA:
undetectable
5vkqD-5ukiA:
undetectable		 5vkqC-5ukiA:
undetectable
5vkqD-5ukiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uki RNA LARIAT
DEBRANCHING ENZYME,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 GLN A 184
ILE A 245
HIS A 236
 None
 0.60A 5z12B-5ukiA:
undetectable		 5z12B-5ukiA:
20.93