SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ukn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.03A 1zzrA-5uknL:
undetectable
1zzrB-5uknL:
undetectable
1zzrA-5uknL:
12.31
1zzrB-5uknL:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.07A 1zzrA-5uknL:
undetectable
1zzrB-5uknL:
undetectable
1zzrA-5uknL:
12.31
1zzrB-5uknL:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.02A 1zzuA-5uknL:
undetectable
1zzuB-5uknL:
undetectable
1zzuA-5uknL:
12.31
1zzuB-5uknL:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.02A 1zzuA-5uknL:
undetectable
1zzuB-5uknL:
undetectable
1zzuA-5uknL:
12.31
1zzuB-5uknL:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
3 / 3 THR L 114
SER L 137
PHE L 118
None
0.81A 3d4sA-5uknL:
undetectable
3d4sA-5uknL:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.05A 3dqrA-5uknL:
undetectable
3dqrB-5uknL:
undetectable
3dqrA-5uknL:
12.25
3dqrB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.09A 3dqrA-5uknL:
undetectable
3dqrB-5uknL:
undetectable
3dqrA-5uknL:
12.25
3dqrB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
5 / 12 PHE L  62
TYR L  49
GLY L  32
SER L  34
LEU L  73
None
1.20A 3e23A-5uknL:
undetectable
3e23A-5uknL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.99A 3jx2A-5uknL:
undetectable
3jx2B-5uknL:
undetectable
3jx2A-5uknL:
12.25
3jx2B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.02A 3jx2A-5uknL:
undetectable
3jx2B-5uknL:
undetectable
3jx2A-5uknL:
12.25
3jx2B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.05A 3jx3A-5uknL:
undetectable
3jx3B-5uknL:
undetectable
3jx3A-5uknL:
12.25
3jx3B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.01A 3jx3A-5uknL:
undetectable
3jx3B-5uknL:
undetectable
3jx3A-5uknL:
12.25
3jx3B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.06A 3jx4A-5uknL:
undetectable
3jx4B-5uknL:
undetectable
3jx4A-5uknL:
12.25
3jx4B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.02A 3jx5A-5uknL:
undetectable
3jx5B-5uknL:
undetectable
3jx5A-5uknL:
12.25
3jx5B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.03A 3jx5A-5uknL:
undetectable
3jx5B-5uknL:
undetectable
3jx5A-5uknL:
12.25
3jx5B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.96A 3jx6A-5uknL:
undetectable
3jx6B-5uknL:
undetectable
3jx6A-5uknL:
12.25
3jx6B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.00A 3jx6A-5uknL:
undetectable
3jx6B-5uknL:
undetectable
3jx6A-5uknL:
12.25
3jx6B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
5 / 12 VAL L  97
VAL L  33
TYR L  30
TYR L  91
GLY L  89
None
1.36A 3medA-5uknL:
undetectable
3medB-5uknL:
undetectable
3medA-5uknL:
undetectable
3medB-5uknL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.97A 3nljA-5uknL:
undetectable
3nljB-5uknL:
undetectable
3nljA-5uknL:
12.25
3nljB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.01A 3nljA-5uknL:
undetectable
3nljB-5uknL:
undetectable
3nljA-5uknL:
12.25
3nljB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.99A 3nlpA-5uknL:
undetectable
3nlpB-5uknL:
undetectable
3nlpA-5uknL:
12.25
3nlpB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.04A 3nlpA-5uknL:
undetectable
3nlpB-5uknL:
undetectable
3nlpA-5uknL:
12.25
3nlpB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 8 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.99A 3nlqA-5uknL:
undetectable
3nlqB-5uknL:
undetectable
3nlqA-5uknL:
12.25
3nlqB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.04A 3nlqA-5uknL:
undetectable
3nlqB-5uknL:
undetectable
3nlqA-5uknL:
12.25
3nlqB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
0.98A 3nlrA-5uknL:
undetectable
3nlrB-5uknL:
undetectable
3nlrA-5uknL:
12.25
3nlrB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 8 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.03A 3nlrA-5uknL:
undetectable
3nlrB-5uknL:
undetectable
3nlrA-5uknL:
12.25
3nlrB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
3 / 3 THR L  26
SER L  27
ARG L  92
None
0.67A 3phnA-5uknL:
undetectable
3phnA-5uknL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.02A 4cx3A-5uknL:
undetectable
4cx3B-5uknL:
undetectable
4cx3A-5uknL:
12.25
4cx3B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.02A 4cx3A-5uknL:
undetectable
4cx3B-5uknL:
undetectable
4cx3A-5uknL:
12.25
4cx3B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.05A 4cx4A-5uknL:
undetectable
4cx4B-5uknL:
undetectable
4cx4A-5uknL:
12.25
4cx4B-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.02A 4cx4A-5uknL:
undetectable
4cx4B-5uknL:
undetectable
4cx4A-5uknL:
12.25
4cx4B-5uknL:
12.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 SER L  34
TYR L  36
TYR L  49
PRO L  55
None
0.68A 5aclA-5uknL:
22.5
5aclA-5uknL:
85.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 TYR L  36
TYR L  49
GLU L  50
PRO L  55
None
0.24A 5aclA-5uknL:
22.5
5aclA-5uknL:
85.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
0.97A 5addA-5uknL:
undetectable
5addB-5uknL:
undetectable
5addA-5uknL:
12.25
5addB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
0.98A 5adeA-5uknL:
undetectable
5adeB-5uknL:
undetectable
5adeA-5uknL:
12.25
5adeB-5uknL:
12.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 8 SER L  34
TYR L  36
GLY L  89
PHE L  98
None
0.25A 5albL-5uknL:
20.6
5albL-5uknL:
68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 8 SER L  34
TYR L  36
GLY L  89
PHE L  98
None
0.29A 5alcL-5uknL:
26.8
5alcL-5uknL:
68.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
None
1.01A 5g0pA-5uknL:
undetectable
5g0pB-5uknL:
undetectable
5g0pA-5uknL:
12.25
5g0pB-5uknL:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ukn DH522UCA FAB
FRAGMENT LIGHT CHAIN

(Macaca
mulatta)
4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
None
1.03A 5g0pA-5uknL:
undetectable
5g0pB-5uknL:
undetectable
5g0pA-5uknL:
12.25
5g0pB-5uknL:
12.25