SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uld'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 ALA A  63
VAL A  66
TRP A  59
None
0.79A 1av2A-5uldA:
undetectable
1av2B-5uldA:
undetectable
1av2A-5uldA:
2.97
1av2B-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 TRP A  59
ALA A  63
VAL A  66
None
0.84A 1av2C-5uldA:
undetectable
1av2D-5uldA:
undetectable
1av2C-5uldA:
2.97
1av2D-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 4 VAL A 401
TRP A 217
ALA A 207
VAL A 405
None
1.35A 1gmkA-5uldA:
undetectable
1gmkB-5uldA:
undetectable
1gmkA-5uldA:
2.97
1gmkB-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 384
LEU A 385
PRO A 387
VAL A 388
LEU A 336
None
1.01A 1gseB-5uldA:
0.7
1gseB-5uldA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 ASN A 378
ILE A 407
ASN A 203
THR A 200
CIT  A 503 ( 3.3A)
None
None
CIT  A 503 (-3.6A)
1.22A 1h7xA-5uldA:
undetectable
1h7xA-5uldA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 ASN A 378
ILE A 407
ASN A 203
THR A 200
CIT  A 503 ( 3.3A)
None
None
CIT  A 503 (-3.6A)
1.22A 1h7xB-5uldA:
undetectable
1h7xB-5uldA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 ASN A 378
ILE A 407
ASN A 203
THR A 200
CIT  A 503 ( 3.3A)
None
None
CIT  A 503 (-3.6A)
1.21A 1h7xC-5uldA:
undetectable
1h7xC-5uldA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 ASN A 378
ILE A 407
ASN A 203
THR A 200
CIT  A 503 ( 3.3A)
None
None
CIT  A 503 (-3.6A)
1.22A 1h7xD-5uldA:
undetectable
1h7xD-5uldA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 8 MET A 228
PHE A 415
ILE A 194
ASN A 151
None
None
None
NA  A 501 ( 3.2A)
1.15A 1pnlA-5uldA:
undetectable
1pnlB-5uldA:
undetectable
1pnlA-5uldA:
18.24
1pnlB-5uldA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 10 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.92A 1pxxA-5uldA:
undetectable
1pxxA-5uldA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.91A 1pxxC-5uldA:
undetectable
1pxxC-5uldA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 ALA A  63
VAL A  66
TRP A  59
None
0.79A 1w5uA-5uldA:
undetectable
1w5uB-5uldA:
undetectable
1w5uA-5uldA:
2.97
1w5uB-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 TRP A  59
ALA A  63
VAL A  66
None
0.71A 1w5uA-5uldA:
undetectable
1w5uB-5uldA:
undetectable
1w5uA-5uldA:
2.97
1w5uB-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 THR A 421
PRO A 418
PRO A 423
CIT  A 503 (-3.1A)
None
None
0.74A 2d55C-5uldA:
undetectable
2d55C-5uldA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 ALA A  63
VAL A  66
TRP A  59
None
0.83A 2izqA-5uldA:
undetectable
2izqB-5uldA:
undetectable
2izqA-5uldA:
2.97
2izqB-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 TRP A  59
ALA A  63
VAL A  66
None
0.71A 2izqC-5uldA:
undetectable
2izqD-5uldA:
undetectable
2izqC-5uldA:
2.97
2izqD-5uldA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 ILE A 426
LEU A 183
MET A 438
ALA A 189
THR A 142
None
1.04A 3a50D-5uldA:
undetectable
3a50D-5uldA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 229
ALA A 143
ALA A 189
PRO A 423
VAL A 427
None
1.20A 3cwkA-5uldA:
undetectable
3cwkA-5uldA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 THR A 154
SER A 146
PHE A 104
None
NA  A 501 (-2.4A)
None
0.74A 3d4sA-5uldA:
1.7
3d4sA-5uldA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 LEU A 345
SER A 342
PHE A 344
ILE A  49
None
0.95A 3ko0B-5uldA:
undetectable
3ko0B-5uldA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 LEU A 345
SER A 342
PHE A 344
ILE A  49
None
0.99A 3ko0S-5uldA:
undetectable
3ko0S-5uldA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP4_A_MIIA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 9 ASN A 151
THR A 154
LEU A 145
ALA A 143
ASN A 203
NA  A 501 ( 3.2A)
None
None
None
None
1.38A 3kp4A-5uldA:
0.0
3kp4B-5uldA:
0.0
3kp4A-5uldA:
14.25
3kp4B-5uldA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 TRP A  59
ALA A  63
VAL A  66
None
0.79A 3l8lA-5uldA:
undetectable
3l8lB-5uldA:
undetectable
3l8lA-5uldA:
2.97
3l8lB-5uldA:
3.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 TRP A  59
ALA A  63
VAL A  66
None
0.68A 3l8lC-5uldA:
undetectable
3l8lD-5uldA:
undetectable
3l8lC-5uldA:
2.97
3l8lD-5uldA:
3.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
1.03A 3nt1A-5uldA:
undetectable
3nt1A-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
1.04A 3nt1B-5uldA:
0.6
3nt1B-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 ALA A 155
ILE A 149
ALA A 107
GLU A 313
GLY A 114
None
1.07A 3nxuA-5uldA:
0.0
3nxuA-5uldA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 THR A 271
GLY A 102
ALA A 105
ALA A 109
LEU A 297
None
1.10A 3p5nA-5uldA:
undetectable
3p5nA-5uldA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 144
ASN A 151
GLY A 192
ALA A 195
LEU A 229
None
NA  A 501 ( 3.2A)
None
None
None
1.07A 3p5nB-5uldA:
undetectable
3p5nB-5uldA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 THR A 271
GLY A 102
ALA A 105
ALA A 109
LEU A 297
None
1.10A 3p5nB-5uldA:
undetectable
3p5nB-5uldA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.89A 3pghD-5uldA:
0.0
3pghD-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 4 GLY A 269
GLY A 266
THR A 264
LEU A 303
None
0.94A 3si7C-5uldA:
undetectable
3si7D-5uldA:
undetectable
3si7C-5uldA:
19.78
3si7D-5uldA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 6 ILE A 149
TRP A 217
ILE A  96
TRP A 275
None
1.49A 3weoA-5uldA:
undetectable
3weoA-5uldA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.98A 4coxC-5uldA:
undetectable
4coxC-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 183
PHE A 415
GLU A 374
THR A 200
SER A 146
None
None
None
CIT  A 503 (-3.6A)
NA  A 501 (-2.4A)
1.12A 4hvcB-5uldA:
undetectable
4hvcB-5uldA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.96A 4otyB-5uldA:
undetectable
4otyB-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.95A 4rrwD-5uldA:
undetectable
4rrwD-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.95A 4rrzD-5uldA:
undetectable
4rrzD-5uldA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
4 / 4 ALA A 206
VAL A 409
GLY A 193
THR A 200
None
None
NA  A 501 (-3.4A)
CIT  A 503 (-3.6A)
0.89A 4ubeA-5uldA:
undetectable
4ubeA-5uldA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 THR A 367
ALA A 366
LEU A 406
LEU A 403
MET A 356
None
1.22A 4xi3D-5uldA:
undetectable
4xi3D-5uldA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
3 / 3 THR A 421
ALA A 414
ASN A 424
CIT  A 503 (-3.1A)
NA  A 502 ( 3.9A)
None
0.55A 5ersA-5uldA:
undetectable
5ersA-5uldA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.94A 5ikqA-5uldA:
0.0
5ikqA-5uldA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.96A 5ikqB-5uldA:
undetectable
5ikqB-5uldA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.90A 5ikrA-5uldA:
undetectable
5ikrA-5uldA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.94A 5ikrB-5uldA:
undetectable
5ikrB-5uldA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 106
None
1.27A 5iktB-5uldA:
0.0
5iktB-5uldA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.79A 5jw1B-5uldA:
undetectable
5jw1B-5uldA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 270
VAL A 295
GLY A 298
ALA A 299
LEU A 303
None
0.79A 5kirA-5uldA:
undetectable
5kirA-5uldA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 9 GLY A 260
VAL A 309
ILE A 267
GLY A 266
ILE A 149
None
0.93A 5vkqC-5uldA:
undetectable
5vkqD-5uldA:
undetectable
5vkqC-5uldA:
13.58
5vkqD-5uldA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 183
PHE A 415
GLU A 374
THR A 200
SER A 146
None
None
None
CIT  A 503 (-3.6A)
NA  A 501 (-2.4A)
1.00A 5xiqA-5uldA:
undetectable
5xiqA-5uldA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 236
PHE A 415
VAL A 441
THR A 200
SER A 146
None
None
None
CIT  A 503 (-3.6A)
NA  A 501 (-2.4A)
1.47A 5xiqB-5uldA:
undetectable
5xiqB-5uldA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)
5uld TRANSPORTER, NADC
FAMILY

(Vibrio
cholerae)
5 / 12 LEU A 183
PHE A 415
GLU A 374
THR A 200
SER A 146
None
None
None
CIT  A 503 (-3.6A)
NA  A 501 (-2.4A)
1.00A 6mn8A-5uldA:
undetectable
6mn8A-5uldA:
19.58