SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ulj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5ulj RAI1
(Scheffersomyces
stipitis) 		5 / 11 PHE A 270
TRP A 273
ALA A 274
LEU A 278
ILE A 337
 None
 0.78A 1ha2A-5uljA:
undetectable		 1ha2A-5uljA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5ulj RAI1
(Scheffersomyces
stipitis) 		3 / 3 ASP A 230
PHE A 178
VAL A 285
 CA  A 401 (-2.6A)
None
None
 0.66A 1kijB-5uljA:
undetectable		 1kijB-5uljA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 8 GLY A 219
GLU A 220
ALA A 221
ILE A 337
 None
 0.65A 2dtjA-5uljA:
undetectable
2dtjB-5uljA:
undetectable		 2dtjA-5uljA:
17.16
2dtjB-5uljA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLY A 227
MET A 111
ILE A 214
VAL A 213
 0WD  A 402 (-3.5A)
None
None
None
 1.17A 3kvvA-5uljA:
undetectable		 3kvvA-5uljA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLY A 227
MET A 111
ILE A 214
VAL A 213
 0WD  A 402 (-3.5A)
None
None
None
 1.16A 3kvvB-5uljA:
undetectable		 3kvvB-5uljA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLY A 227
MET A 111
ILE A 214
VAL A 213
 0WD  A 402 (-3.5A)
None
None
None
 1.16A 3kvvE-5uljA:
undetectable		 3kvvE-5uljA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLY A 227
MET A 111
ILE A 214
VAL A 213
 0WD  A 402 (-3.5A)
None
None
None
 1.13A 3kvvF-5uljA:
undetectable		 3kvvF-5uljA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5ulj RAI1
(Scheffersomyces
stipitis) 		5 / 12 MET A 111
MET A  80
LEU A  83
ILE A 104
LEU A 127
 None
 1.11A 3olsB-5uljA:
undetectable		 3olsB-5uljA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 7 SER A 140
GLU A 143
ILE A 144
ASN A 139
 None
 1.04A 4d39B-5uljA:
undetectable		 4d39B-5uljA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		3 / 3 TYR A 119
THR A 328
GLU A 266
 None
 0.52A 4df3A-5uljA:
undetectable		 4df3A-5uljA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		3 / 3 TYR A 119
THR A 328
GLU A 266
 None
 0.55A 4df3B-5uljA:
undetectable		 4df3B-5uljA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLY A 227
MET A 111
ILE A 214
VAL A 213
 0WD  A 402 (-3.5A)
None
None
None
 1.11A 4e1vF-5uljA:
undetectable		 4e1vF-5uljA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 5ulj RAI1
(Scheffersomyces
stipitis) 		5 / 12 MET A 111
MET A  80
LEU A  83
ILE A 104
LEU A 127
 None
 1.08A 4j24C-5uljA:
undetectable		 4j24C-5uljA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5ulj RAI1
(Scheffersomyces
stipitis) 		5 / 12 MET A 111
MET A  80
LEU A  83
ILE A 104
LEU A 127
 None
 1.07A 4j26B-5uljA:
undetectable		 4j26B-5uljA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLU A 143
ASP A 141
ASP A 126
ARG A 354
 None
 1.30A 4kcnA-5uljA:
undetectable		 4kcnA-5uljA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 6 GLU A 143
ASP A 141
ASP A 126
ARG A 354
 None
 1.30A 4kcnB-5uljA:
undetectable		 4kcnB-5uljA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 5 PHE A  25
PHE A  23
LEU A 244
PRO A  19
 None
 0.82A 4o8zA-5uljA:
undetectable		 4o8zA-5uljA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 5ulj RAI1
(Scheffersomyces
stipitis) 		4 / 8 ILE A 310
LYS A 311
ILE A 324
ASN A 325
 None
 0.68A 4ou1A-5uljA:
undetectable		 4ou1A-5uljA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUO_D_PFLD402_1
(PROTON-GATED ION
CHANNEL)		 5ulj RAI1
(Scheffersomyces
stipitis) 		5 / 9 THR A 365
SER A 356
THR A 363
THR A 361
SER A 360
 None
 1.30A 5muoA-5uljA:
0.5
5muoB-5uljA:
0.5
5muoC-5uljA:
undetectable
5muoD-5uljA:
undetectable
5muoE-5uljA:
0.5		 5muoA-5uljA:
10.05
5muoB-5uljA:
10.05
5muoC-5uljA:
10.05
5muoD-5uljA:
10.05
5muoE-5uljA:
10.05