SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ulu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 4 GLY A2105
LEU A2094
GLY A2062
ARG A2103
 None
 1.40A 1j7kA-5uluA:
undetectable		 1j7kA-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5ulu CADHERIN-23
(Mus
musculus) 		5 / 9 LEU A2256
ILE A2188
PHE A2151
VAL A2210
ALA A2171
 None
 0.82A 2m9qA-5uluA:
undetectable		 2m9qA-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 VAL A2121
VAL A2122
THR A2050
ARG A2084
 None
 1.17A 3bjwA-5uluA:
undetectable		 3bjwA-5uluA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 VAL A2121
VAL A2122
THR A2050
ARG A2084
 None
 1.17A 3bjwC-5uluA:
undetectable		 3bjwC-5uluA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5ulu CADHERIN-23
(Mus
musculus) 		5 / 9 ASP A2072
THR A2124
ASN A2125
ASP A2074
ASP A2039
 CA  A2303 (-2.1A)
None
CA  A2303 (-2.9A)
CA  A2303 ( 3.3A)
None
 1.48A 3sfuA-5uluA:
undetectable		 3sfuA-5uluA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 6 VAL A2217
LEU A2235
ILE A2188
VAL A2258
 None
 0.84A 4a9kA-5uluA:
undetectable		 4a9kA-5uluA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 5ulu CADHERIN-23
(Mus
musculus) 		5 / 9 ILE A2188
PHE A2208
TYR A2231
GLN A2204
VAL A2219
 None
 1.25A 4g1bC-5uluA:
undetectable		 4g1bC-5uluA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 4 TYR A2117
THR A2108
VAL A2104
ILE A2141
 None
 1.35A 4jx1F-5uluA:
undetectable		 4jx1F-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 6 LEU A2032
LEU A1958
VAL A1957
PHE A2033
 None
 0.97A 4uswA-5uluA:
undetectable		 4uswA-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 6 TYR A1941
ILE A2034
VAL A1957
ALA A1943
 None
 0.93A 5cu6A-5uluA:
undetectable		 5cu6A-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 LEU A2032
PHE A2033
LEU A1955
PHE A1987
 None
 1.21A 5iy5P-5uluA:
undetectable
5iy5W-5uluA:
undetectable		 5iy5P-5uluA:
undetectable
5iy5W-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 6 LEU A2032
PHE A2033
LEU A1955
PHE A1987
 None
 1.14A 5w97C-5uluA:
undetectable
5w97J-5uluA:
undetectable		 5w97C-5uluA:
undetectable
5w97J-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 LEU A2032
PHE A2033
LEU A1955
PHE A1987
 None
 1.14A 5x1fC-5uluA:
undetectable
5x1fJ-5uluA:
undetectable		 5x1fC-5uluA:
undetectable
5x1fJ-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 LEU A2032
PHE A2033
LEU A1955
PHE A1987
 None
 1.11A 5xdxC-5uluA:
undetectable
5xdxJ-5uluA:
undetectable		 5xdxC-5uluA:
undetectable
5xdxJ-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 5 LEU A2032
PHE A2033
LEU A1955
PHE A1987
 None
 1.22A 5xdxP-5uluA:
undetectable
5xdxW-5uluA:
undetectable		 5xdxP-5uluA:
undetectable
5xdxW-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5ulu CADHERIN-23
(Mus
musculus) 		4 / 8 ASP A2196
ARG A2225
GLU A2162
ASP A2262
 None
 1.17A 6mn4B-5uluA:
undetectable		 6mn4B-5uluA:
undetectable