SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ulv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 10 LEU A 136
ALA A 145
TYR A 270
LEU A 130
GLN A 131
 None
 1.24A 1aqbA-5ulvA:
undetectable		 1aqbA-5ulvA:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 GLY A  10
ASP A  34
ILE A  35
TYR A  66
ALA A  79
 None
 0.43A 1cetA-5ulvA:
44.5		 1cetA-5ulvA:
44.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		3 / 3 TRP A 202
ARG A 185
THR A 203
 None
 0.99A 1df7A-5ulvA:
undetectable		 1df7A-5ulvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 10 VAL A 116
VAL A  81
VAL A  99
VAL A 103
ILE A  69
 None
 1.09A 1fe2A-5ulvA:
undetectable		 1fe2A-5ulvA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 LEU A 136
ALA A 145
TYR A 270
LEU A 130
GLN A 131
 None
 1.29A 1hbpA-5ulvA:
undetectable		 1hbpA-5ulvA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 LEU A 136
ALA A 145
TYR A 270
LEU A 130
GLN A 131
 None
 1.41A 1iiuA-5ulvA:
undetectable		 1iiuA-5ulvA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 LEU A 136
ALA A 145
TYR A 270
LEU A 130
GLN A 131
 None
 1.42A 1kt6A-5ulvA:
undetectable		 1kt6A-5ulvA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 LEU A 136
ALA A 145
TYR A 270
LEU A 130
GLN A 131
 None
 1.32A 1kt7A-5ulvA:
undetectable		 1kt7A-5ulvA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		3 / 3 ASP A 113
ASP A  73
LYS A 140
 None
 1.10A 1lqtB-5ulvA:
6.4		 1lqtB-5ulvA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		3 / 3 ASP A 113
ASP A  73
LYS A 140
 None
 1.12A 1lquB-5ulvA:
6.6		 1lquB-5ulvA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NCW_H_BEZH601_0
(IMMUNOGLOBULIN IGG2A)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  48
TYR A  60
LEU A  45
GLY A  42
GLY A  62
 None
 1.47A 1ncwH-5ulvA:
undetectable
1ncwL-5ulvA:
undetectable		 1ncwH-5ulvA:
20.82
1ncwL-5ulvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 TYR A  66
THR A 120
GLY A  80
ILE A  69
LEU A 130
 None
 1.14A 1r30A-5ulvA:
undetectable		 1r30A-5ulvA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 TYR A  66
THR A 120
GLY A  80
ILE A  69
LEU A 130
 None
 1.14A 1r30B-5ulvA:
undetectable		 1r30B-5ulvA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 10 ALA A  48
TYR A  60
LEU A  45
GLY A  42
GLY A  62
 None
 1.48A 1ruaH-5ulvA:
undetectable
1ruaL-5ulvA:
undetectable		 1ruaH-5ulvA:
20.82
1ruaL-5ulvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  48
TYR A  60
LEU A  45
GLY A  42
GLY A  62
 None
 1.49A 1rulH-5ulvA:
undetectable
1rulL-5ulvA:
undetectable		 1rulH-5ulvA:
20.82
1rulL-5ulvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUM_H_BEZH1601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  48
TYR A  60
LEU A  45
GLY A  42
GLY A  62
 None
 1.48A 1rumH-5ulvA:
undetectable
1rumL-5ulvA:
undetectable		 1rumH-5ulvA:
20.82
1rumL-5ulvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  48
TYR A  60
LEU A  45
GLY A  42
GLY A  62
 None
 1.46A 1rupH-5ulvA:
undetectable
1rupL-5ulvA:
undetectable		 1rupH-5ulvA:
20.82
1rupL-5ulvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 ILE A 240
ASN A 121
ILE A 117
VAL A  30
LEU A   8
 None
 1.26A 3a51A-5ulvA:
undetectable		 3a51A-5ulvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 ILE A 240
ASN A 121
ILE A 117
VAL A  30
LEU A   8
 None
 1.24A 3a51D-5ulvA:
undetectable		 3a51D-5ulvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 ILE A 240
ASN A 121
ILE A 117
VAL A  30
LEU A   8
 None
 1.22A 3a51E-5ulvA:
undetectable		 3a51E-5ulvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 GLN A  41
PRO A  40
ASP A  34
VAL A 103
ALA A 102
 None
 1.03A 3n23A-5ulvA:
undetectable		 3n23A-5ulvA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 GLN A  41
PRO A  40
ASP A  34
VAL A 103
ALA A 102
 None
 1.02A 3n23C-5ulvA:
undetectable		 3n23C-5ulvA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 ALA A  68
ASP A  65
GLY A 106
ILE A 107
ALA A  72
 None
 1.20A 3n3iA-5ulvA:
undetectable		 3n3iA-5ulvA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  68
ASP A  65
GLY A 106
ILE A 107
LEU A   8
 None
 1.05A 3u7sB-5ulvA:
undetectable		 3u7sB-5ulvA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  68
ASP A  65
GLY A 106
ILE A 107
LEU A   8
 None
 0.98A 3u7sA-5ulvA:
undetectable		 3u7sA-5ulvA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 ALA A  68
ASP A  65
GLY A 106
ILE A 107
LEU A   8
 None
 1.05A 3u7sB-5ulvA:
undetectable		 3u7sB-5ulvA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 9 GLY A  71
GLY A 106
ILE A 107
LEU A   8
VAL A  31
 None
 1.05A 3u7sB-5ulvA:
undetectable		 3u7sB-5ulvA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 11 ASP A  46
ALA A  19
TYR A  60
LEU A   8
VAL A  30
 None
 1.22A 5hw4B-5ulvA:
undetectable		 5hw4B-5ulvA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5ulv MALATE DEHYDROGENASE
(Methylobacterium
extorquens) 		5 / 12 VAL A  39
GLY A  15
GLY A  10
ILE A 119
ALA A 236
 None
 1.15A 5x7fA-5ulvA:
5.5		 5x7fA-5ulvA:
24.00