SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5umq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 8 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.82A 2dyrC-5umqA:
undetectable
2dyrJ-5umqA:
undetectable		 2dyrC-5umqA:
undetectable
2dyrJ-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 8 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.81A 2eilC-5umqA:
undetectable
2eilJ-5umqA:
undetectable		 2eilC-5umqA:
undetectable
2eilJ-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 9 ILE A  53
ILE A   8
PHE A 119
THR A  72
LEU A  76
 None
 1.18A 2m9qA-5umqA:
undetectable		 2m9qA-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 6 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.82A 3abkP-5umqA:
undetectable
3abkW-5umqA:
undetectable		 3abkP-5umqA:
undetectable
3abkW-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 8 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.81A 3ag4C-5umqA:
undetectable
3ag4J-5umqA:
undetectable		 3ag4C-5umqA:
undetectable
3ag4J-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 6 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.85A 5x19P-5umqA:
undetectable		 5x19P-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 5 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.80A 5x1bP-5umqA:
undetectable		 5x1bP-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 7 LEU A 121
PHE A 119
PHE A 111
LEU A  88
 None
 0.87A 5x1fP-5umqA:
undetectable
5x1fW-5umqA:
undetectable		 5x1fP-5umqA:
undetectable
5x1fW-5umqA:
undetectable