SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5umw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5umw GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 12 PHE A 120
SER A 124
LEU A  56
VAL A  44
VAL A  10
 None
 1.22A 1q23B-5umwA:
undetectable		 1q23B-5umwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5umw GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 11 PHE A 120
SER A 124
LEU A  56
VAL A  44
VAL A  10
 None
 1.21A 1q23F-5umwA:
undetectable		 1q23F-5umwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5umw GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 11 PHE A 120
SER A 124
LEU A  56
VAL A  44
VAL A  10
 None
 1.25A 1q23I-5umwA:
undetectable		 1q23I-5umwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 5umw GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 10 LEU A 130
THR A 131
VAL A  88
LEU A  26
PHE A  21
 None
 1.41A 3tbgC-5umwA:
undetectable		 3tbgC-5umwA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5umw GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 12 PHE A 120
SER A 124
LEU A  56
VAL A  44
VAL A  10
 None
 1.35A 3u9fH-5umwA:
undetectable
3u9fI-5umwA:
undetectable		 3u9fH-5umwA:
undetectable
3u9fI-5umwA:
undetectable