SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5umx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		3 / 3 ASP A  21
ARG A  41
LYS A  20
 None
 1.02A 3wipG-5umxA:
undetectable		 3wipG-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 6 VAL A  11
LEU A  71
ILE A 114
VAL A  45
 None
 0.95A 4a9kA-5umxA:
undetectable		 4a9kA-5umxA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 9 LEU A  73
LEU A 116
GLY A 115
VAL A  90
VAL A  92
 None
 1.34A 4c9kB-5umxA:
undetectable		 4c9kB-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 10 LEU A  73
LEU A 116
GLY A 115
VAL A  90
VAL A  92
 None
 1.33A 4c9nB-5umxA:
undetectable		 4c9nB-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 9 LEU A  73
LEU A 116
GLY A 115
VAL A  90
VAL A  92
 None
 1.35A 4c9pA-5umxA:
undetectable		 4c9pA-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		5 / 10 LEU A  73
LEU A 116
GLY A 115
VAL A  90
VAL A  92
 None
 1.36A 4c9pB-5umxA:
undetectable		 4c9pB-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE
(Streptomyces
sp.
CB03234) 		4 / 8 ASN A 112
TRP A  42
PHE A   9
THR A  62
 None
 1.28A 5hqaA-5umxA:
undetectable		 5hqaA-5umxA:
8.32