SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		3 / 3 ALA A 241
VAL A  12
TRP A  15
 None
 0.91A 1c4dC-5uq6A:
undetectable
1c4dD-5uq6A:
undetectable		 1c4dC-5uq6A:
6.03
1c4dD-5uq6A:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		3 / 3 TRP A  15
ALA A 241
VAL A  12
 None
 0.78A 1c4dC-5uq6A:
undetectable
1c4dD-5uq6A:
undetectable		 1c4dC-5uq6A:
6.03
1c4dD-5uq6A:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.36A 1d4fC-5uq6A:
undetectable		 1d4fC-5uq6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 11 HIS A  94
TYR A 217
LEU A 201
LEU A 141
THR A 140
 None
 1.39A 1dmyA-5uq6A:
undetectable		 1dmyA-5uq6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 10 TYR A 187
THR A  57
ASN A 144
HIS A 221
HIS A 195
 None
None
None
FE  A 403 (-3.3A)
PO4  A 404 (-3.8A)
 1.46A 1ivvA-5uq6A:
undetectable		 1ivvA-5uq6A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		3 / 3 ARG A 157
ASP A  52
ASN A 243
 None
FE  A 403 ( 2.7A)
None
 0.94A 1nbhA-5uq6A:
undetectable		 1nbhA-5uq6A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		3 / 3 ARG A 157
ASP A  52
ASN A 243
 None
FE  A 403 ( 2.7A)
None
 0.94A 1nbhD-5uq6A:
undetectable		 1nbhD-5uq6A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.47A 1v8bB-5uq6A:
undetectable		 1v8bB-5uq6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		4 / 7 LEU A 238
PRO A 188
GLY A  90
ASP A  52
 None
None
None
FE  A 403 ( 2.7A)
 0.92A 2ddwB-5uq6A:
2.2		 2ddwB-5uq6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		4 / 7 TYR A 259
LEU A 234
ASN A 232
TYR A 227
 None
 1.42A 2w98A-5uq6A:
undetectable
2w98B-5uq6A:
1.5		 2w98A-5uq6A:
20.54
2w98B-5uq6A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 GLY A  51
GLY A  13
ALA A  11
LEU A  48
VAL A 139
 None
 0.90A 2zulA-5uq6A:
undetectable		 2zulA-5uq6A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		3 / 3 SER A  76
GLU A  28
ASP A  73
 None
 0.85A 3bwmA-5uq6A:
undetectable		 3bwmA-5uq6A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.46A 3ce6A-5uq6A:
undetectable		 3ce6A-5uq6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 3ce6C-5uq6A:
undetectable		 3ce6C-5uq6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 GLY A  51
GLY A  13
ALA A  11
LEU A  48
VAL A 139
 None
 0.90A 3dmhA-5uq6A:
undetectable		 3dmhA-5uq6A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.39A 3glqA-5uq6A:
undetectable		 3glqA-5uq6A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.41A 3glqB-5uq6A:
undetectable		 3glqB-5uq6A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 11 VAL A  12
TRP A  15
HIS A 186
ASN A  53
GLU A  28
 None
None
FE  A 403 ( 3.4A)
None
None
 1.44A 4c1fA-5uq6A:
undetectable
4c1fB-5uq6A:
2.1		 4c1fA-5uq6A:
22.05
4c1fB-5uq6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 ALA A 274
GLY A  13
GLY A 240
ASP A  14
ALA A  11
 None
None
None
FE  A 402 ( 3.1A)
None
 0.93A 4lg1A-5uq6A:
undetectable		 4lg1A-5uq6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 ALA A 274
GLY A  13
GLY A 240
ASP A  14
ALA A  11
 None
None
None
FE  A 402 ( 3.1A)
None
 0.94A 4lg1C-5uq6A:
undetectable		 4lg1C-5uq6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.38A 4lvcB-5uq6A:
undetectable		 4lvcB-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.39A 4lvcC-5uq6A:
undetectable		 4lvcC-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		6 / 12 LEU A 120
ILE A 133
ILE A 124
ILE A 278
PHE A  46
PRO A 125
 None
 1.39A 4odrA-5uq6A:
undetectable
4odrB-5uq6A:
undetectable		 4odrA-5uq6A:
15.29
4odrB-5uq6A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.49A 4pfjA-5uq6A:
undetectable		 4pfjA-5uq6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.42A 4pgfA-5uq6A:
undetectable		 4pgfA-5uq6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5axaA-5uq6A:
undetectable		 5axaA-5uq6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5axaC-5uq6A:
undetectable		 5axaC-5uq6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A  92
PRO A 153
ASP A  52
ASN A  91
HIS A 223
 PO4  A 404 (-3.7A)
None
FE  A 403 ( 2.7A)
PO4  A 404 ( 2.6A)
FE  A 402 (-3.4A)
 1.26A 5dv4A-5uq6A:
4.0		 5dv4A-5uq6A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		4 / 5 LEU A 238
HIS A 221
THR A 198
CYH A 219
 None
FE  A 403 (-3.3A)
None
None
 1.43A 5eu8A-5uq6A:
undetectable		 5eu8A-5uq6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5hm8A-5uq6A:
2.0		 5hm8A-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8B-5uq6A:
2.0		 5hm8B-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8C-5uq6A:
undetectable		 5hm8C-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8D-5uq6A:
undetectable		 5hm8D-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8E-5uq6A:
undetectable		 5hm8E-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8F-5uq6A:
undetectable		 5hm8F-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8G-5uq6A:
undetectable		 5hm8G-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5hm8H-5uq6A:
undetectable		 5hm8H-5uq6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 ILE A 133
VAL A 276
ALA A 274
VAL A 237
GLY A 242
 None
 1.19A 5igiA-5uq6A:
undetectable		 5igiA-5uq6A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		4 / 6 GLY A 272
SER A 239
GLY A  13
ASN A  31
 None
 0.72A 5k4pA-5uq6A:
undetectable		 5k4pA-5uq6A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.43A 5m5kA-5uq6A:
undetectable		 5m5kA-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5m5kB-5uq6A:
2.0		 5m5kB-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.43A 5m5kC-5uq6A:
undetectable		 5m5kC-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.45A 5m66A-5uq6A:
undetectable		 5m66A-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5m66B-5uq6A:
undetectable		 5m66B-5uq6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		4 / 7 TYR A 118
GLN A 101
ASP A  93
HIS A 186
 None
None
None
FE  A 403 ( 3.4A)
 1.48A 5ov9B-5uq6A:
undetectable		 5ov9B-5uq6A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.43A 5v96A-5uq6A:
undetectable		 5v96A-5uq6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.42A 5v96B-5uq6A:
2.1		 5v96B-5uq6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.42A 5v96C-5uq6A:
undetectable		 5v96C-5uq6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.44A 5v96D-5uq6A:
undetectable		 5v96D-5uq6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 THR A 138
ASP A  93
ASP A  14
LEU A  88
GLY A 185
 None
None
FE  A 402 ( 3.1A)
None
None
 1.17A 5v96D-5uq6A:
undetectable		 5v96D-5uq6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.42A 6aphA-5uq6A:
undetectable		 6aphA-5uq6A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
ASP A  14
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 ( 3.1A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.26A 6exiA-5uq6A:
undetectable		 6exiA-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
HIS A 223
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 (-3.4A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.38A 6exiA-5uq6A:
undetectable		 6exiA-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
ASP A  14
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 ( 3.1A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.30A 6exiB-5uq6A:
undetectable		 6exiB-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
HIS A 223
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 (-3.4A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.34A 6exiB-5uq6A:
undetectable		 6exiB-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
ASP A  14
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 ( 3.1A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.27A 6exiC-5uq6A:
undetectable		 6exiC-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
HIS A 223
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 (-3.4A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.38A 6exiC-5uq6A:
undetectable		 6exiC-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
ASP A  14
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 ( 3.1A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.31A 6exiD-5uq6A:
undetectable		 6exiD-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 HIS A 195
THR A 198
HIS A 223
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 (-3.4A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.43A 6exiD-5uq6A:
undetectable		 6exiD-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.42A 6gbnA-5uq6A:
undetectable		 6gbnA-5uq6A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.41A 6gbnB-5uq6A:
undetectable		 6gbnB-5uq6A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 12 LEU A  95
HIS A  92
ASP A 146
GLY A  51
HIS A 186
 None
PO4  A 404 (-3.7A)
PO4  A 404 ( 4.6A)
None
FE  A 403 ( 3.4A)
 1.41A 6gbnD-5uq6A:
undetectable		 6gbnD-5uq6A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5
(Sus
scrofa) 		5 / 10 ALA A 100
TYR A 104
PHE A  67
PHE A  54
VAL A  59
 NAG  A 401 (-3.5A)
None
None
None
None
 1.38A 6hu9C-5uq6A:
undetectable		 6hu9C-5uq6A:
21.71